January 2025
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This study evaluated the antioxidant properties of two Lonchocarpus species leaves extracts. It also profiled the phenolic constituents of their active fractions using HPLC. Of the four solvent fractions obtained, ethyl acetate of Lonchocarpus cyanescens (LC) had the highest antioxidant activity [MCA (IC50), DPPH (IC50), FRAP, TAC, TFC and TPC with 0.673 ± 0.061 μg/mL, 0.245 ± 0.007 μg/mL, 177.6 ± 3.7 mg AAE/g, 202.5 ± 3.6 mg AAE/g, 1,323.1 ± 16.7 μg CE/g and 1244.3 ± μg GAE/g values, respectively]. The processing of the groundnut oil was observed to compromise its natural defence system. Gallic acid was the best of the three antioxidant agents used to stabilize groundnut oil followed by the ethyl acetate fraction of LC, and butylated hydroxyanisole (BHA) the least. It can be concluded that gallic acid and ethyl acetate fraction of LC could be used to replace BHA implicated in aetiology of cancer but safety and acceptability of their use in vegetable oil should be investigated.