Francesca Scaramuzzi's research while affiliated with Università degli Studi di Bari Aldo Moro and other places

Publications (2)

Article
Introduction: The aim was to evaluate and stratify early cardiovascular risk of transsexuals undergone pharmacological and/or surgical gender reassignment. Methods: Fifty-six transsexuals were divided into two groups: 1- undergone gonadectomy (orchiectomy for trans women and hystero-annessiectomy for trans men); group 2- hormone replacement ther...

Citations

... Our data corroborate that ovariectomy and the consequent drop in estradiol promote vascular dysfunction (31). The data also support clinical findings by Ciccone et al. (32) that under GAHT, endothelial function is decreased in gonadectomized transgender people versus transgender people with no surgical procedures. In our study, ovariectomy plus testosterone showed a trend to greater vascular dysfunction, although the data were not statistically significant. ...
... Observational studies of transgender women on various estrogen and androgen blockers show inconsistent associations with blood pressure. In two studies in which CPA was used as the androgen blocker and the estrogen regimen consisted of ethinyl estradiol or transdermal estradiol, both SBP and DBP increased significantly from baseline to 1 or 2 years after starting hormones [42,43]. We recommend regular BP monitoring of all transgender adults and suggest closer monitoring in transgender men initiating GAHT, particularly for patients with concomitant cardiovascular comorbidities. ...