Field F. Willingham’s research while affiliated with Emory University and other places

... Another example of a wider use of neuroanatomy by health care professionals different from neurologists/neurosurgeons is the implementation of US to study the peripheral nervous system: on top of the most obvious diagnostic application for diagnosis of neuropathy [3,4], US can be used, in fact, to guide procedures such as local anesthesia and pain management targeting a specific branch of the peripheral nervous system [11][12][13][14]. ...

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3D Digital tools in neuro-anatomy teaching: from peer-to-peer tutoring to clinically oriented approaches

... In this regard, it should be emphasized that the documentation of an abnormal sphincteric basal pressure in type 2 SOD may be difficult in clinical practice because SOM has been mostly abandoned due to its invasiveness and poor diagnostic reliability and the secretin test is not available in most centers [46,47]. However, despite the encouraging results published years ago, in recent studies on large series of patients, the percentage of recurrent AP was reported to vary from 17.4% to 40% of cases in both groups [48,49]. In these cases, sphincter dysfunction was probably not the cause of RAP, although it was documented. ...

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Endoscopic Management of Recurrent Acute Pancreatitis

... Especial controversia tiene el concepto de que DEO cause pancreatitis aguda recurrente (PAR). El estudio longitudinal RESPOND, que está en vías de ser publicado, puede responder algunos de estos conflictos [6] . ...

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Gastroenterología Latinoamericana Disfunción del esfínter de Oddi (DEO) ¿Qué hay de nuevo? Sphincter of Oddi Dysfunction (SOD) What's new?

... Increasing evidence supports the effectiveness of rectal NSAIDs, aggressive hydration, and prophylactic pancreatic stents in preventing PEP [2,3,14]. The combined use of these measures has been shown to further reduce PEP risk [32,33]. Second, the publication of the first clinical practice guidelines for PEP in 2015 [14], along with the revised guidelines for the management of AP in the same year [34], may have increased awareness of PEP risk factors and preventive strategies among Japanese endoscopists. ...

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Current status and trends in ERCP and post-ERCP pancreatitis in Japan: a nationwide observational study

... Over the past decade, these challenges have been overcome through advancements in ultrasound resolution and the availability of smaller needle electrodes [46]. As a result, RFA, including percutaneous, endoscopic, and intraoperative approaches, is now considered a feasible, safe, and effective option for patients with insulinomas who are unable or unwilling to undergo surgical resection [6,[14][15][16]20,[23][24][25][26][27][28][29][30]32,33,[35][36][37][38][39][40][41][42][43][46][47][48][49][68][69][70]. This study demonstrates that percutaneous ultrasound-guided RFA is an effective and safe procedure for treating insulinomas and their metastases in dogs, potentially offering a new alternative approach for managing neuroendocrine pancreatic tumors. ...

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Percutaneous Ultrasound-Guided Radiofrequency Ablation as a Therapeutic Approach for the Management of Insulinomas and Associated Metastases in Dogs

... Radiofrequency ablation (RFA) has emerged as a promising minimally invasive technique for managing pancreatic cancer, particularly in unresectable cases. RFA uses focal thermal energy to induce cell death through coagulative necrosis and protein denaturation [155]. Recent studies have demonstrated RFA's potential to reduce tumor progression, promote an abscopal effect, and induce significant remodeling of the tumor stroma and immune response [156]. ...

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Recent Advances and Challenges in the Treatment of Advanced Pancreatic Cancer: An Update on Completed and Ongoing Clinical Trials

... Prospective and multicenter studies are crucial for minimizing biases and ensuring the generalizability of findings [58][59][60][61]. For example, a multicenter study identified SII > 510 as an independent predictive factor for overall survival following radical cholecystectomy for GBC [62]. ...

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Detecting the preoperative peripheral blood systemic immune-inflammation index (SII) as a tool for early diagnosis and prognosis of gallbladder cancer

... EUS clearly identifies the origin of the lesion, reveals the stratification of the digestive tract wall, and provides information on echo intensity, echo uniformity, and the boundary of the lesion. Despite these advantages, the endoscopic ultrasound appearance of glomus tumor has similar manifestations with other submucosal tumors, which are often difficult to identify (Table 1) (2,8). In color Doppler images, blood flow within the glomus tumor is sometimes visible. ...

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Case report: One case of precise resection of gastric glomus tumor by gastroscopy combined with laparoscopy

... 6,42 Chronic pancreatitis is more common in men than in women and in Black individuals than in Caucasians, peaking at 46-55 years of age. 9,43 Etiology Although several causes of chronic pancreatitis have been described in the literature, most patients eventually develop typical clinical and morphological features. 10 Risk factors include alcohol use (in 42%-77% of cases), smoking (over 60% in some studies), and genetic mutations (present in 10%). ...

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E V I D E N C E -B A S E D R E V I E W 16. Pain in chronic pancreatitis

... In the case described in the present report, the patient developed extensive retroperitoneal necrosis extending into the posterior rectum following severe acute pancreatitis. The value of necrosectomy has been widely reported in recent years, including laparoscopic-assisted pancreatic necrosectomy (LAPN) [7] and endoscopic necrosectomy [8]. In the present manuscript, we report our institution's method for choledochoscope-assisted pancreatic necrosectomy and provide the results of our experience. ...

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Choledochoscope-Guided Necrosectomy for Retroperitoneal and Posterior Rectal Post-Pancreatitis Necrosis