Fadwa El Amrani’s research while affiliated with Centre Hospitalier Universaitaire IBN Sina de Rabat and other places

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Publications (17)


Imatinib (Glivec®) lichenoid eruption
  • Article

December 2013

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15 Reads

Nouvelles Dermatologiques

F. El Amrani

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K. El Morabite

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[...]

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Imatinib is a tyrosinekinase inhibitor used in the treatment of chronic myeloid leukemia and gastrointestinal stromal tumors (GIST). Cutaneous side effects with this treatment are common but lichenoid drug eruption is exceptional. We report a new case.


[Neurofibromatosis type 1]
  • Article
  • Full-text available

November 2013

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100 Reads

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3 Citations

Pan African Medical Journal

La neurofibromatose de type 1(NF1) ou maladie de Von Recklinghausen est la plus frequente des phacomatoses. C’est une affection autosomique dominante, ou les mutations de novo concernent 50 % des patients. Son diagnostic est clinique avec des criteres definis. Les manifestations cutanees arrivent au premier plan avec les taches cafe au lait (TCL), les lentigines axillaires et inguinales et les neurofibromes cutanes. Les autres criteres diagnostiques comprennent le gliome des voies optiques, les nodules de Lisch, la dysplasie sphenoidale ou l’amincissement de la corticale des os longs ainsi qu’un parent du premier degre atteint de NF1. Aucun traitement curatif n’est disponible a ce jour. Nous rapportons l’observation d’une patiente de 32 ans, qui consulte pour une tumeur geante de la face laterale du sein gauche. L’examen dermatologique retrouvait les criteres de la NF1 : plus de 6 TCL de plus de 1,5 cm, des lentigines diffuses, des neurofibromes cutanes et un neurofibrome plexiforme geant prenant toute la partie laterale du sein gauche, mesurant environ 25 cm de grand axe. L’examen ophtalmologique a revele de multiples nodules de Lisch bilateraux. L’IRM cerebrale et les radiographies osseuses etaient sans anomalie. Une exerese chirurgicale du neurofibrome plexiforme a ete realisee. Il n y a pas eu de recidive locale apres deux ans de suivi.

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Citations (6)


... In our patients, there was no other skin lesions or medicine usage and her lesions are idiopathic. In differential diagnosis, seborrheic keratosis, hyperkeratosis due to itching, mycosis fungoides, and pigmented basal cell carcinoma are included [6]. ...

Reference:

Nevoid hyperkeratosis of the nipple and areola
Successful Treatment with Calcipotriol for Nevoid Hyperkeratosis of the Nipples
  • Citing Article
  • November 2013

Clinical Medicine Insights Dermatology

... Several treatments including surgery, chemotherapy and radiotherapy have been tried with often mixed results. No curative treatment is yet available [24], it is so far symptomatic [2] [9] [10] [18] [25]. The management of NF1 is multidisciplinary, involving ophthalmologists, dermatologists, maxillofacial surgeons, neu-rosurgeons and plastic surgeons [19]. ...

[Neurofibromatosis type 1]

Pan African Medical Journal

... PCR allows an equivalent result in 24-48 hours. 5 The diagnosis requires the search for other tuberculous sites, in particular an attack on the urinary tract, by performing an intravenous urography, a direct bacteriological examination.These examinations were normal in our patient. Similarly, the HIV infection is essential because of the frequency and increased morbidity and mortality of tuberculosis in this context.Our patient's HIV serology was negative. ...

[Primary penile tuberculosis.]
  • Citing Article
  • October 2013

Annales de Dermatologie et de Vénéréologie

... Large SK is in fact an unusual presentation and it is rarely documented in the literature (Table 1). [3][4][5][6][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Giant SK have been notably described in genital areas. [4][5][6][17][18][19][20][22][23][24] The size of reported giant SK varies from 4.5 to 25 cm in greatest diameter with an average size of 9.8 cm. ...

Kératoses séborrhéiques géantes de siège inhabituel
  • Citing Article
  • November 2012

Annales de Dermatologie et de Vénéréologie

... Of these, the acanthotic subtype is the most common variant. The acanthotic type, demonstrates hyperkeratosis, marked acanthosis with basaloid cells, papillomatosis and presence of horn cysts or pseudocysts [3]. The cause of genital SK is as yet unknown, but there may be a possible role of chronic friction [2]. ...

Giant seborrhoeic keratosis in an unusual site
  • Citing Article
  • November 2012

Annales de Dermatologie et de Vénéréologie