Evrim Aktepe's research while affiliated with T.C. Süleyman Demirel Üniversitesi and other places

Publications (59)

Article
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Introduction: There has been no study in the literature evaluating serum tumor necrosis factor-like weak inducer of apoptosis (TWEAK) levels in attention-deficit/hyperactivity disorder (ADHD). Therefore, we performed the present study to specifically measure serum TWEAK levels to see whether or not its eventual alterations might have an etiopathog...
Preprint
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The aim of this study is to determine functioning of adults with Autism Spectrum Disorders (ASDs) diagnosed in childhood and also depression and burnout levels among their parents. 261 adults with ASDs and their parents were recruited for the study. Both parents completed the Beck Depression and Maslach Burnout Inventories and reported the function...
Article
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The aim of this study was to determine whether serum VEGF, IGF-1, and HIF-1α levels differed between Autism Spectrum Disorder (ASD) patients and healthy controls. A total of 40 children with ASD and 40 healthy controls aged 4–12 years were included. Serum levels of VEGF, IGF-1, and HIF-1α were measured using commercial enzyme-linked immunosorbent a...
Article
Objectives: The present study assessed the obese adolescents' health-related quality of life (HRQoL) based on both adolescent-reported and maternal-reported questionnaires to clarify adolescent-related psychiatric factors, maternal psychiatric factors, and body mass index (BMI) percentile variables that independently affect the quality of life (Qo...
Article
Objective This study aimed to determine the prevalence and comorbidities of attention-deficit hyperactivity disorder (ADHD) by evaluating a large-scale nation-wide sample of children. Method The inclusion criterion was being enrolled as a 2nd, 3rd, or 4th-grade student. A semi-structured diagnostic interview (K-SADS-PL), DSM-IV-Based Screening Sca...
Article
Objective This study aimed to investigate serum zonulin and claudin-5 levels of children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and healthy controls by controlling the parameters such as age, sex and body mass index (BMI) percentile which are known to affect these parameters. Method A total of 80 treatment-naive child...
Article
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Amaç: Çalışmamızda aşırı kilolulu/obezite tanısı olan ergenlerde psikiyatrik bozuklukların yaygınlığını ve dağılımını araştırmak, ayrıca normal vücut ağırlığı olan ergenlerle psikiyatrik tanı dağılımlarını karşılaştırmak amaçlanmıştır. Gereç ve Yöntem: Çalışmaya Süleyman Demirel Üniversitesi Hastanesi Pediatrik Endokrinoloji Bilim Dalı Polikliniği'...
Article
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Objectives:In our study, it was aimed to investigate the frequency and distribution of psychiatric disorders in adolescents with overweight/obesity, and to compare psychiatric distribution with adolescents with normal weight.Materials and Methods:One hundred six adolescents between the ages of 12 and 18 years, who applied to the Pediatric Endocrino...
Article
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Objective Observations of sex differences have led some scientists to doubt whether the neuroendocrine system is involved in attentiondeficit/ hyperactivity disorder (ADHD) etiology. One of the interesting study subjects in this context is prenatal steroid hormone exposure. The aim of the present study was to replicate and extend previous work by a...
Article
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Objective: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with underlying pathogenesis and etiological factors not fully understood. We assumed that galectin-3, which is also linked with inflammatory responses, may play an important role in the ethiopathogenesis of ADHD. In this study, we aimed to investigate whet...
Article
Background: Obsessive–compulsive disorder (OCD), a chronically debilitating neuropsychiatric disorder, is characterized by distinctive and recurrent obsessions and/or compulsions. An increasing number of evidence indicates that sophisticated interactions between different neurobiological factors play a part in OCD etiology, but the certain underlyi...
Article
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Background: Adolescents are psychologically more unstable and are at risk for acne and problematic Internet usage (PIU). Objectives: We aimed to evaluate PIU and characteristics of Internet usage in adolescents with acne and compared it with a control group. In addition, the relationship between psychiatric variables and problematic Internet use wa...
Article
Background: The effects of isotretinoin on suicide, social anxiety and obsessive-compulsive symptoms in adolescents with acne have not been sufficiently investigated. Objective: This study aimed to evaluate the quality of life, depression, anxiety, suicide, social anxiety, and obsessive-compulsive symptoms of adolescents receiving systemic isotr...
Article
ABSTRACT Aim: The aim of this study was to determine the prevalence of childhood psychopathologies in Turkey. Method: A nation-wide, randomly selected, representative population of 5830 children (6–13 yearsold) enrolled as a 2nd,3rd or 4th grade student in 30 cities were evaluated for presence of a psychiatric or mental disorder by a Sociodemograph...
Article
Full-text available
Amaç Bu çalışmada suça sürüklenen çocukların sosyodemografik ve klinik özelliklerinin incelenmesi amaçlanmıştır. Gereç ve Yöntem Süleyman Demirel Üniversitesi Tıp Fakültesi Çocuk ve Ergen Ruh Sağlığı ve Hastalıkları Anabilim Dalına Ocak 2014-Aralık 2018 tarihleri arasında suça sürüklendiği iddiasıyla rapor düzenlenmesi için yönlendirilen ve psikiya...
Article
Background Since adolescents are psychologically more unstable, the emergence of acne vulgaris during adolescence makes this disease a focal point of concern for many individuals. Aim In this study, psychiatric comorbidity and levels of self‐injurious behavior, suicide probability, life satisfaction, self‐esteem and loneliness in adolescents with...
Article
Aim: To determine the prevalence of affective disorders in Turkey among a representative sample of Turkish population. Methods: This study was conducted as a part of the “The Epidemiology of Childhood Psychopathology in Turkey” (EPICPAT-T) Study, which was designed by the Turkish Association of Child and Adolescent Mental Health. The inclusion cri...
Article
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Objective: Childhood masturbation (CM) is the self-stimulation of the genitalia by a child with the intention of obtaining pleasure and is frequently associated with physical distress signs and symptoms. In this study, we aimed to examine the temperament and character traits of mothers of a clinical sample of infants and young children, who present...
Article
Children with autism spectrum disorder (ASD) often exhibit the symptoms of attention-deficit/hyperactivity disorder (ADHD). Methylphenidate (MPH) is commonly used for ADHD symptoms in children with ASD. However, these children are reported to be more sensitive to side effects of MPH. The most common side effects of MPH are insomnia, decreased appet...
Article
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Objective: Adolescents are a potential group for developing internet addiction due to their frequent use of the internet. Therefore, detecting adolescents with possible internet addiction (PIA) and revealing the relationship between their internet use and their mental health is quite important for the development of preventive measures. This study...
Article
Objective: The aim of this study was to evaluate the self-concept and psychosocial status measured by the levels of social phobia and loneliness in a sample of adolescent patients with different malocclusions and to explain the relationships, if any, between malocclusions. Methods: This study was performed on 90 (41 females and 49 males) orthodo...
Article
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The aim of this study was to examine risk factors related to cyber bullying and victimization. The study was carried out with 160 adolescents applying to the Child/Adolescent Psychiatry Outpatient Clinic of the Faculty of Medicine of Silleyman Demirel University in Isparta, Turkey. Data was collected through using the Sodo-Demographic Information F...
Article
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Objective: Empathy skills and personal conflicts which may change over time by social, environmental and educational factors, are both important components for a succesful patient-physician relationship. We sought to investigate the empathy levels and conflict tendencies in medical students considering the phase of medical education Method: One hun...
Article
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Background and Design: Acne vulgaris is a dermatological disorder mainly seen in adolescents. Psychiatric morbidity has been reported in these patients. The aim of the present study was to investigate the quality of life, loneliness and life satisfaction levels in adolescents with acne vulgaris. Materials and Methods: A total of 264 adolescents wit...
Article
Objective: Acne vulgaris occurs mostly during adolescence, a time when social and physical changes occur at the maximum level, and identity formation is a matter. In adolescence, when the perfect look is idealized, and in societies where physical attractiveness is important, acne can be a devastating disease. This study aims to evaluate the peer re...
Article
Pathological fire setting behavior is characterized by various types of fire setting behavior that lasts at least 6 months. This behavior can be observed both during childhood and adolescence and it develops as a result of the complex interaction between individual, social and environmental factors. Sample population based studies show that fire se...
Article
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The aim of the present study was to detect both sociodemographic factors related to possible Internet addiction and the prevalence of this addiction, as well as to determine the relationship between possible Internet addiction and self-injurious behavior, life satisfaction, and the level of loneliness in adolescents attending high school in the cit...
Article
Incest is defined as any form of sexual contact between immediate relatives without regarding the ages, and con-sent of the participants. The cases presented are two adolescents impregnated as a result of sexual abuse from their brothers (one case from the older brother and the other case from the younger brother). The adolescent who was impregnate...
Article
Objective: The aim of the present study is to determine the demographic and clinical characteristics as well as psychiatric diagnoses of children and adolescents who applied to Süleyman Demirel University Medical Faculty Child Psychiatry polyclinic in order to get a judicial report. Method: In children and adolescents sent to Süleyman Demirel Unive...
Article
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Background and Design: Atopic dermatitis is a chronic, inflammatory skin disease characterized by itchy skin lesions. Since adolescents are intensely interested in their physical appearance, chronic skin diseases in this period can adversely affect the development of self esteem. Atopic dermatitis is a skin disease that affects the appearance and t...
Article
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Aim: The aim of the present study is to inquire into the evaluation and monitoring processes of the psychiatry consultations requested within the period of 4 years and 3 months in Suleyman Demirel University (SDU) Medical Faculty Children-Adolescent Mental Health and Disorders Department. Method: In-patients and out-patients monitored by the clinic...
Article
Objective: The aim of this study is the detection of a lifetime history of self injurious behavior as well as the determination of the relationship between self-injurious behavior and suicide attempt, suicidal ideation, anxiety and depression levels. Methods: A cross-sectional analytic study was planned in high school students. The schools were str...
Article
Objective: The purpose is to determine some clinical features of self-injurious behavior, family functions and selfesteem in self-injurious adolescents in comparison to a control group. Apart from that, one purpose is to evaluate the relationships between self-esteem and some clinical features regarding self-injurious behavior in the case group. Me...
Article
Objective: The present study aims to examine psychiatric and organic comorbidities, the pregnancy and birth complications in children diagnosed with mental retardation in the Department of Child-Adolescent Mental Health and Disorders within the scope of a two-year period. Method: Children and adolescents diagnosed with mental retardation by Süleyma...
Article
Much as an increase in the use of psychotropic drugs is observed in children and adolescents over the last decade, the endocrine and metabolic side effects of these drugs can limit their use. Atypical antipsychotics can cause many side effects, which are not suitable for the developmental periods of children and adolescents, such as those related w...
Article
Objective: The study aims at discussing self-esteem and quality of life in children and adolescents with the ages of 7-15 who are diagnosed with Attention Deficit Hyperactivity Disorder (ADHD). Method: 50 children and adolescents with ADHD diagnosis and their parents are examined and matched 30 children and adolescents who as control group and thei...
Article
Self injury is a kind of behavior which begins in early adolescence and difficult to determine because remains suppressed. Most often forms are to cut and hit own. To be exposed to sexual abuse and stressfully life events are known as risk factors for self injurious behavior. High anxiety, depression and hostility levels, decrease of self esteem, s...
Article
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Objective: The aim of this study is to present the sociodemographic features and comorbid disorders of children and adolescents with conversion disorder which referred from Trabzon and surrounding cities to Child and Adolescent Psychiatry Department of Karadeniz Technical University Faculty of Medicine. Method: The hospital files and child and adol...
Article
Objective: Data about sociodemographic features, enuresis type, etiological types, family history, copying strategies, and approach to drug therapy of families towards enuresis, comorbid disorders, conducted treatment modalities are aimed to inquire in this study. Method: Data of 61 patients, who admitted to our policlinic and had enuresis nocturna...
Article
To find out if the quality of life (QOL) and self-concept of the children with cerebral palsy (CP) was different from that of children without disability, to investigate predictive variables that could affect self-concept and QOL. A total of 40 children with CP and 46 age-matched peers were included. The baseline characteristics including sex, type...
Article
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Pregnancy, delivery complications and treatment approach were evaluated in 153 cases diagnosed with attention deficit hyperactivity disorder in the State Hospital of Antalya in the Child and Adolescent Psychiatry Polyclinic. Most of the cases had been delivered vaginally (74.5%). The most frequent delivery complication was asphyxia/hypoxia (15.6%)....
Article
Although lithium continues to be regarded as the treatment of choice for bipolar disorder (BD), the clinical use of this mood stabilizer is associated with a narrow therapeutic range. Relatively minor increases in serum concentrations may induce serious adverse sequelae, and concentrations within therapeutic range may result in toxic reactions. The...
Article
People have been forced to immigrate due to various reasons. After immigration, when they start to live away from their home, they can find it difficult to assimilate into a new culture. This results in their feeling lonely and furthermore some psychiatric problems. Relation between immigration and mental problems has been discussed in various stud...
Article
SOCIODEMOGRAPHIC FEATURES OF CHILD AND ADOLESCENTS ADMITTED TO KARADENİZ TECHNICAL UNIVERSITY MEDICAL FACULTY CHILD OUTPATIENT CLINIC WITH SUICIDE ATTEMPT Assesment of sociodemographic and psychiatric characteristics of attempted suicide in children and adolescents. The aim of this study is to identify risk factors and sociodemographic, psychiatric...
Article
Full-text available
Amaç: Bu çalışmada cinsel istismar mağduru olan çocuk ve ergenlerin klinik ve sosyodemografik özelliklerini, bölümümüze başvuru şekillerini saptamak amaçlandı. Yöntem: Karadeniz Teknik Üniversitesi Tıp Fakültesi Çocuk-Ergen Ruh Sağlığı ve Hastalıkları Anabilim Dalına 2005 ve 2007 yılları arasındaki süre içinde başvurmuş olan çocuk-ergenlerin kişise...

Citations

... In Portugal, the data from the last survey in 2018 show that around 34% of the overall population had obesity, and about 18% of children and 24% of the adolescents had pre-obesity [3]. A high body mass index (BMI) during childhood and adolescence is related to various non-communicable chronic diseases, such as diabetes [4,5] and cardiovascular diseases [6], and also leads to a low quality of life [7], and, if not, these complications are extended into later life [8]. Another component of obesity is abdominal obesity, characterized by a high accumulation of fat mass in the abdominal region, which, in turn, increases the risk of cardiovascular disease [9], cancer [10], and diabetes [11], reduces the immune system function, and increases inflammatory levels [12,13]. ...
... Also, several comorbid diagnoses, such as anxiety, depression, personality disorders, antisocial behaviors, and substance use disorders could be seen in children and adolescents with ADHD [4][5][6][7]. Oppositional defiant disorder and conduct disorder are also common comorbidities that lead to significant impairment [8]. ...
... In contrast, several reports, including this one, document changes in IGF-1 levels in the periphery of children with autism 30-32 . The significantly increased peripheral blood levels of IGF-1 immunoreactivity observed in our subjects with autism compared to controls are in agreement with the results reported by Mills et al. 32 and Şimşek et al. 34 , who showed IGF-1 increases in ASD plasma and serum, respectively. Mills et al. 32 restricted their study sample to only boys between 4 and 8 years old, whereas Şimşek et al. 34 found a significantly higher level of IGF-1 protein in a mixed population of boys and girls ages 4-12, consistent with the broader age range of 5-15 years and both sexes (25% females) in our study. ...
... deletion syndrome and associated with neuroinflammation. Aydogan Avsar et al. [138] have also found higher levels of serum claudin-5 in children with attention-deficit/hyperactivity disorder compared to age matched controls suggesting a potential change in BBB/NVU function. ...
... O mesmo Conselho publicou estudo sobre o tema em seu periódico científico (Pérez & Rodrigues, 2013 (Frazier et al., 2004). É mais provável que desatenção, hiperatividade e impulsividade prejudiquem o desempenho em testes de inteligência (Antshel et al., 2007;Işık et al., 2020;Kim et al., 2020). No entanto, adultos com altas habilidades possuem mais sintomas característicos do TDAH em relação à população geral; porém, essa diferença não foi significativa na amostra infantil (Minahim & Rohde, 2015). ...
... According to our knowledge, there is no study in the literature that examines the impact of BMI percentiles, child psychiatric factors and maternal psychiatric factors on QoL. In addition, ADHD is common in obese patients [28,29], and ADHD alone affects QoL negatively [30]. Despite all this, according to our knowledge, ADHD symptoms were not taken into account in previous studies assessing the QoL in patients with obesity. ...
... 8,9 Altered composition (dysbiosis) of the intestinal microbiota increases intestinal permeability, the translocation of bacterial products and inflammatory responses as a result of immune activation in several diseases, including MDD. [10][11][12][13][14] Several studies have reported changes in the intestinal microbiota [15][16][17] in patients with depression, and intestinal permeability in other psychiatric disorders. [18][19][20] Communication between the microbiota and the brain may involve neural, endocrine and immune pathways, including translocated bacterial products. 8 Water-avoidance stress in rats increases intestinal permeability, 21 and chronic mild stress leads to the translocation of bacterial products and neuroinflammatory responses by immune activation. ...
... With increasing time spent on the Internet, individuals may have difficulty with developing healthy interpersonal relationships and have less time to engage in social activities, contributing to depression [19]. There is an important association between PIU, adolescents' loneliness, and social anxiety, as anxiety and depression interact with PIU [22]. When perceived stress increases, individuals may attempt to relieve the stress by overusing their smartphone, but as such relief is only transient, a feeling of sadness increases from the unresolved stress [23,24]. ...
... In addition to ADHD, possible association between other psychiatric disorders and serum zonulin levels was investigated. Esnafoglu et al. found higher serum zonulin levels among patients diagnosed as autism spectrum disorders (21), Kilic et al. found higher serum zonulin levels in patients diagnosed as bipolar disorder (22) and Isik et al. also investigated serum zonulin levels among patients diagnosed as obsessive compulsive disorders and found no significant difference between patients and controls (23). As presented, there are studies investigating the association between psychiatric disorders and zonulin. ...