Eun Young Choi's research while affiliated with Sungshin Women's University and other places
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Publications (284)
Purpose : This study is intended to understand the life experience of middle-aged women who are marriage immigrants, focusing on their climacteric experiences, by conducting an in-depth exploration of their life experiences and the essential structure of their experiences in overcoming such challenges. Methods : Data were collected through in-depth...
Purpose:
We establish an accurate and rapid diagnostic method for pathogen detection in infectious uveitis using nanopore metagenomic next-generation sequencing (NGS).
Methods:
In eight patients with suspected infectious uveitis, we prospectively compared the accuracy and time taken for pathogen identification between conventional diagnostic met...
Background:
Elucidating nurses' adaptation to changes in the early stage of an infectious disease epidemic is necessary to promote nurses' coping with and adapting to situations in which new infectious diseases are predicted periodically.
Aim:
To explore nurses' adaptation to changes in COVID-19 wards in South Korea.
Methods:
In-depth intervie...
Quantitative and qualitative research explore various social phenomena using different methods. However, there has been a tendency to treat quantitative studies using complicated statistical techniques as more scientific and superior, whereas relatively few qualitative studies have been conducted in the medical and healthcare fields. This review ai...
Objectives:
Attempts to understand patient safety using administrative data in Korea have been rare. This study develops a Korean patient safety incident code classification system and identifies its characteristics to boost diagnosis code usage for assessing patient safety.
Methods:
Based on existing literature, we selected Korean Standard Clas...
Background
We compared low-salt preference between patients with major chronic diseases, also known as non-communicable diseases (hereinafter referred to as ‘“major NCD patients’”), and the general population.
Methods
We used data extracted from the Korea Community Health Survey Community during the period of 2008–2019. We evaluated the low-salt p...
Aims
To clarify second victim symptoms subgroups, explore the factors affecting profile membership and determine how desired support strategies differ between the subgroups.
Design
A cross‐sectional study using an online survey.
Methods
A total of 378 Korean staff nurses directly involved in patient safety incidents were recruited between Decembe...
Purpose:
To investigate the association between intermittent fasting and age-related macular degeneration (AMD) in general elderly population.
Design:
A cross-sectional study using a population-based, government-led survey data, Korean National Health and Nutrition Examination Survey (KNHANES).
Methods:
A total of 4,504 subjects aged ≥ 55 year...
Objective:
The aim of the study was to investigate the feasibility of using administrative data to screen adverse events in Korea.
Methods:
We used a diagnosis-related groups claims data set and the information of the checklist of healthcare quality improvement (a part of the value incentive program) to verify adverse events in fiscal year 2018....
Purpose: The aim of this study was to evaluate whether perivascular space (PVS) severity and retinal ganglion cell layer (GCL) thickness differed based on the stage of diabetic retinopathy (DR) and the cognitive status in patients with DR.
Methods: A total of 81 patients with DR (51 in the non-proliferative group and 30 in the proliferative group)...
Late-stage dry age-related macular degeneration (AMD) or geographic atrophy (GA) is an irreversible blinding condition characterized by degeneration of retinal pigment epithelium (RPE) and the associated photoreceptors. Clinical and genetic evidence supports a role for dysfunctional lipid processing and accumulation of harmful oxidized lipids in th...
Background
Perfectionism in the medical field turns healthcare professionals into second victims of patient safety incidents. They suffer physically and psychologically, which makes them consider changing occupations. Nursing students may also have similar negative experiences during clinical practice.
Objective
To describe the second victim pheno...
Myopia has been discussed as a risk factor for glaucoma. In this study, we characterized the relationship between ametropia and patterns of visual field (VF) loss in glaucoma. Reliable automated VFs (SITA Standard 24-2) of 120,019 eyes from 70,495 patients were selected from five academic institutions. The pattern deviation (PD) at each VF location...
Women’s participation in society has been increasing; however, they often remain overloaded with housework, and this gender role difference can hinder their work-life balance in Korea. Therefore, this study classified latent profiles according to job quality indices for South Korean female employees and examined the characteristics of each profile...
Background
Sturge-Weber syndrome is a disorder marked by a distinctive facial capillary malformation, neurological abnormalities, and ocular abnormalities such as glaucoma and choroidal hemangioma.
Case presentation
We report a case of progressively formed retinal vessel malformation in a premature male infant with Sturge-Weber syndrome and retino...
As a result of mass media development, disaster-related information, such as the severity of damage, can be easily shared; thus, the issue of consequent indirect trauma has become as important as that of direct trauma. This study developed a scale to measure the degree of indirect trauma caused by media exposure to social disasters and then verifie...
Objective
To model the global test-retest variability of visual fields (VFs) in glaucoma.
Design
Retrospective cohort study
Participants
8,088 VFs of 4,044 eyes from 4,044 participants.
Methods
We selected two reliable VFs (SITA 24-2) per eye measured with the Humphrey Field Analyzer within 30 days of each other. Each VF contained fixation losse...
Purpose:
To investigate intereye associations of visual field (VF) defects.
Methods:
We selected 24-2 VF pairs of both eyes from 63,604 patients tested on the same date with mean deviation (MD) ≥ -12 dB. VFs were decomposed into one normal and 15 defect patterns previously identified using archetypal analysis. VF pattern weighting coefficients w...
The present study investigated physicians' perceptions regarding the need for, effects of, and barriers to disclosure of patient safety incidents (DPSI). An anonymous online questionnaire survey was conducted to investigate physicians' perception regarding DPSI, in particular of when DPSI was needed in various situations and of methods for facilita...
Objectives
The aim of this study was to investigate the scope and severity of the second victim problem among nurses by examining the experiences and effects of patient safety incidents (PSIs) on them.
Participants/setting
492 nurses who had experienced PSIs and provide direct care in South Korean medical institutions.
Design
A cross-sectional st...
Objectives:
This study aimed to explore nurses' perceptions regarding disclosure of patient safety incidents.
Methods:
An anonymous online survey was conducted, and results were compared with those of the general public using the same questionnaire in a previous study.
Results:
Among 689 nurses, 96.8% of nurses felt major errors should be disc...
Purpose:
The purpose of this study was to classify the spatial patterns of retinal nerve fiber layer thickness (RNFLT) and assess their associations with visual field (VF) loss in glaucoma.
Methods:
We used paired reliable 24-2 VFs and optical coherence tomography scans of 691 eyes from 691 patients. The RNFLT maps were used to determine the RNF...
Purpose:
The onset and progression of optic neuropathies like glaucoma often occurs asymmetrically between the two eyes of a patient. Interocular circumpapillary retinal nerve fiber layer thickness (cpRNFLT) differences could detect disease earlier. To apply such differences diagnostically, detailed location specific norms are necessary.
Methods:...
Maintaining a healthy work–life balance is important for both males and females. Nevertheless, gender segregation still exists in labor markets in South Korea. Therefore, this study aimed to investigate differences in occupational characteristics, job quality indices, and work-life balance between male and female employees. This study was a seconda...
Current medical school education focuses on acquiring appropriate knowledge with relatively little interest in developing the career selection skills of medical students. We investigated medical students’ perceptions of career problems and the required types of career counseling programs. Five focus group discussions were held with 23 medical stude...
Background:
Medical professionals who experience patient safety incidents (PSIs) are vulnerable to emotional pain and other difficulties; such individuals are referred to as "second victims." This study quantitatively examines the characteristics of physicians' experiences of PSIs, along with the consequent difficulties and levels of post-traumati...
Since the first case was contracted by coronavirus disease-19 (COVID-19) in Daegu, Korea in February 2020, about 6,800 cases and 130 deaths have been reported on April 9, 2020. Recent studies have reported that patients with diabetes showed higher mortality and they had a worse prognosis than the group without diabetes. In poorly controlled patient...
Objective:
The study aimed to investigate the impacts of patient safety incident (PSI) experienced by the general public.
Methods:
We conducted a self-administered online survey, in which we examined the following experiences of the patients and the caregivers: the level of harm induced by PSIs, difficulties due to PSIs, posttraumatic stress dis...
Background: Physicians are in the most critical position vis-à-vis disclosure of patient safety incidents (DPSI), and improper perceptions of DPSI among them could be a major barrier to proper execution of DPSI in clinical practice. The present study investigated physicians’ perceptions regarding the need for, effects of, and barriers to DPSI.
Meth...
Purpose:
To investigate the role of sex on retinal nerve fiber layer (RNFL) thickness at 768 circumpapillary locations based on OCT findings.
Design:
Population-based cross-sectional study.
Participants:
We investigated 5646 eyes of 5646 healthy participants from the Leipzig Research Centre for Civilization Diseases (LIFE)-Adult Study of a pre...
Purpose:
The purpose of this study was to determine nurses' perceptions of the disclosure of patient safety incidents (DPSI), which is known to be effective in reducing medical litigation and improving the credibility of medical professionals.
Methods:
Three focus group discussions were conducted with 20 nurses using semistructured guidelines. T...
Objectives:
This study investigated how the essential elements of informed consent are realised during the consent process and examined the challenges in obtaining genuine informed consent in Korea.
Methods:
Through purposive sampling, we recruited 21 subjects from those participating in anticancer drug research since 2013. We undertook 1:1 in-d...
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Background:
Health forecasting has been used in an attempt to provide timely and tailored meteorological information to patients and healthcare providers so that they might take appropriate actions to mitigate health risks and manage healthcare-related needs. This study examined the in-depth perceptions of healthcare providers and the general publ...
Purpose
To investigate the efficacy, safety, and anatomical outcomes associated with intravitreal anti-vascular endothelial growth factor (VEGF) treatment of retinopathy of prematurity (ROP).
Methods
We performed a retrospective review of intravitreal anti-VEGF (bevacizumab or ranibizumab) treatment of 153 eyes (83 infants) diagnosed with ROP at t...
Purpose:
To compare changes in the retinal layer thickness and visual outcomes in patients undergoing epiretinal membrane (ERM) surgery with or without internal limiting membrane (ILM) peeling.
Methods:
Seventy-six eyes of 76 patients who underwent ERM surgery from January 2013 to March 2015 at the Department of Ophthalmology, Yonsei University...
Atopic dermatitis (AD) is a chronic inflammatory skin disorder with a complex etiology involving the immune response. Recent studies have demonstrated the role of certain probiotics in the treatment and prevention of AD. However, the mechanism by which these probiotics regulate the immune system remains unclear. In this study, we examined the immun...
There are several established prognostic scoring systems for community-acquired pneumonia (CAP). The Pneumonia Severity Index (PSI) is a prediction rule consisting of 20 variables to identify low-risk patients with CAP. Although PSI had high discrimination ability, it is complex to calculate and difficult to use in busy hospital settings. The CURB-...
Full descriptions of the 8 hypothetical cases in this study.
(DOCX)
To introduce disclosure of patient safety incidents (DPSI) into a specific country, evidence of the effectiveness of DPSI is essential. Since such a disclosure policy has not been adopted in South Korea, hypothetical cases can be used to measure the effectiveness of DPSI. We evaluated the effectiveness of DPSI using hypothetical cases in a survey w...
Objectives:
Previous studies have demonstrated that the general public can report various patient safety incidents (PSIs) that are not identified by other methods. In this study, we investigated the characteristics of PSIs that the general public experience in Korea.
Methods:
In face-to-face surveys, participants were asked to report the frequen...
This study evaluated the near-infrared (NIR) fluorescent probe Sorbitol-ZW800-1 as tracer for targeted tumor imaging of multiple cancer types. Preliminarily, Sorbitol-ZW800-1 conjugate was validated in vivo on breast (MCF-7) cancer cell lines. Subsequently, the tracer was tested in xenograft mouse models with malignant breast (MDA-MB-231), lung (NC...
Epidermal growth factor-like repeats and discoidin I-like domain 3 (Edil3) is an extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif that binds integrin. Recently, Edil3 has been implicated in various biological processes, including angiogenesis and cellular differentiation. It can inhibit inflammatory bone destruction. The objective...
Effects of Edil3 treatment on cell proliferation.
MC3T3-E1 cells were cultured with recombinant Edil3 protein at designated concentration in growth medium. After 24 h or 48 h of incubation, cell proliferation was detected by BrdU assay kit (Cell signaling Technology).
(TIF)
Effects of ECM protein Edil3, fibronectin, and osteopontin on matrix mineralization.
MC3T3-E1 cells were treated with fibronectin (FN, 200 ng/ml, Sigma-Aldrich), osteopontin (OPN, 200 ng/ml, R&D Systems), or Edil3 (200 ng/ml, R&D Systems) separately and maintained in osteogenic medium containing 50 μg/ml ascorbic acid and 5 mM β-glycerophosphate. A...
Effects of Edil3 on phosphorylation of Akt, ERK, and p38.
MC3T3-E1 cells were incubated with growth medium for the indicated time period in the absence or presence of Edil3 (200 ng/ml). Cells were harvested and immunoblot analysis was performed using specific antibodies against p-Akt, p-ERK, p-p38, and β-actin. Note that Edil3 treatment increased p...
GTPase regulator associated with focal adhesion kinase-1 (Graf1) is an essential component of the GPI-enriched endocytic compartment (GEEC) endocytosis pathway. Mutations in the human graf1 gene are associated with acute myeloid leukemia (AML), but its normal role in myeloid cell development remains unclear. We show that Graf, the Drosophila orthol...
Objectives:
Many countries and organizations have promoted the disclosure of patient safety incidents (DPSI). However, reporting frequency and quality of DPSI fall short of patient and caregiver' expectations. In this study, we examined the attitudes toward DPSI of the general public representing the Korean population.
Methods:
Survey questions...
The hospital standardized mortality ratio (HSMR) is a widely used generic measure for assessing quality of hospital care in many countries. However, the validity of HSMR as a quality indicator is still controversial. We critically reviewed characteristics of HSMR and suggested how to use HSMR as a quality indicator in the Korean setting. The associ...
Objectives: The Health Insurance Review and Assessment Service (HIRA) has been implementing quality assessment program to improve the quality of care for acute stroke patients. The purpose of this study was to evaluating the performance of the program. Methods: We compared the assessment results of the year 2008 or 2009 with those of the year 2014....
Background and Objectives
The aim of this study was to investigate the effect of pulmonary valve replacement (PVR) on exercise capacity and determine cardiopulmonary exercise (CPEX) parameters associated with improvement in right ventricle (RV) function.
Subjects and Methods
We retrospectively analyzed CPEX and magnetic resonance imaging parameter...
Neonatal Marfan syndrome (nMFS) is considered to be on the most severe end of the spectrum of type I fibrillinopathies. The common features of nMFS include ascending aortic dilatation, severe mitral and/or tricuspid valve insufficiency, ectopia lentis, arachnodactyly, joint contractures, crumpled ear, loose skin, and pulmonary emphysema.We describe...
Background: The purpose of this study was to develop risk-adjustment models for acute stroke mortality that were based on data from Health Insurance Review and Assessment Service (HIRA) dataset and to evaluate the validity of these models for comparing hospital performance. Methods: We identified prognostic factors of acute stroke mortality through...
Background To identify the prevalence and related factors for vitamin D deficiency in the patients who admitted to the medical intensive care unit (ICU) of a Korean tertiary care hospital. Methods We retrospectively analyzed the data from ICU patients requiring mechanical ventilation (MV) for a period of > 48 h to identify the prevalence and associ...
This is the odds ratios of osteopenia, osteoporosis, and a low BMD by sarcopenia.
(DOCX)
This is the multivariate regression analysis of body indexes contributing to a low BMD.
(DOCX)
Background
A decrease in bone mineral density (BMD) is a systemic consequence of chronic obstructive pulmonary disease (COPD). Past reports have rarely examined any correlation between sarcopenia and BMD. We investigated the relationship cross-sectionally between the presence of sarcopenia and BMD reduction in COPD patients.
Methods
COPD patients...
This is the multivariate linear regression analysis of body indexes for each T-score.
(DOCX)
This is the baseline characteristics of the sarcopenia and non-sarcopenia patients.
(DOCX)
This is the T-score and prevalence of bone disease in each group.
(DOCX)
This is the correlation analysis of body indexes for each T-score.
(DOCX)
This is the odds ratios of osteopenia, osteoporosis, and a low BMD by sarcopenia in each body weight group (subgroup analysis).
(DOCX)
This research analyzed the effect of β-glucan that is expected to alleviate the production of the inflammatory mediator in a macrophagocyte, which was processed by the lipopolysaccharide (LPS) of Escherichia. The incubated layer was used for a nitric oxide (NO) analysis. The DNA-binding activation of the small unit of NF-κB was measured using the E...
Purpose: This study was conducted to assess predictor variables of husbands in multicultural families and examine the relationship among variables after setting up a hypothetical model including influencing factors, so as to provide a framework necessary for developing nursing interventions of domestic violence.
Methods: The participants were 260 h...