Esra Dilek’s research while affiliated with Çanakkale Onsekiz Mart University and other places

What is this page?


This page lists works of an author who doesn't have a ResearchGate profile or hasn't added the works to their profile yet. It is automatically generated from public (personal) data to further our legitimate goal of comprehensive and accurate scientific recordkeeping. If you are this author and want this page removed, please let us know.

Publications (1)


(a) Schematic representation related to synthesis of cyclomatrix p(CTP‐co‐MMCA) microparticles, (b) FTIR spectra of HCCP, MMCA, p(CTP‐co‐MMCA) microparticles.
SEM image of (a) p(CTP‐co‐MMCA) (1 : 1) microparticles, (b) p(CTP‐co‐MMCA) (1 : 2) microparticles, (c) and (d) p(CTP‐co‐MMCA) (1 : 3) microparticles, (e) EDX spectra and elemental contents of p(CTP‐co‐MMCA) (1 : 3) microparticles.
(a) SEM image of p(CTP‐co‐MMCA)@Au microparticles and elemental mapping for Au, (b) SEM image of p(CTP‐co‐MMCA)@Ag microparticles and elemental mapping for Ag.
(a) TEM image of p(CTP‐co‐MMCA)@Au microparticles (b) TEM image of p(CTP‐co‐MMCA)@Ag microparticles, (c) and (d) XRD patterns of p(CTP‐co‐MMCA), p(CTP‐co‐MMCA)@Au, p(CTP‐co‐MMCA)@Ag microparticles.
(a) General XPS spectrum of p(CTP‐co‐MMCA)@Au microparticles (b) high resolution XPS spectrum of Au 4 f energy level, (c) general XPS spectrum of p(CTP‐co‐MMCA)@Ag microparticles, (d) high resolution XPS spectrum of Ag 3d energy level.

+1

Investigation of Drug Release Behavior of Cyclomatrix Polyphosphazene Microparticles Decorated with Gold and Silver Nanoparticles
  • Article
  • Publisher preview available

January 2024

·

18 Reads

Esra Dilek

·

Hava Ozay

In this study, p(CTP‐co‐MMCA) microparticles, a novel cyclomatrix polyphosphazene, were synthesized. Among the p(CTP‐co‐MMCA) polymeric structures, p(CTP‐co‐MMCA) (1 : 3) with a high surface amine group was found to be in the form of microparticles after detailed structural and morphological characterization. These microparticles were modified with Au⁰ and Ag⁰ nanoparticles using two different green reductants. The antimicrobial activities of p(CTP‐co‐MMCA) microparticles and their Au⁰ and Ag⁰ composites against P.Aeruginosa ATCC 27853, S.Aureus ATCC 6538 and C.Albicans were investigated. Metal composites were found to have better antimicrobial activity. Cyclomatrix p(CTP‐co‐MMCA) microparticles with antimicrobial properties and their Au⁰ and Ag⁰ composites were also used for the release of Ceftriaxone sodium and RNA. Cyclomatrix p(CTP‐co‐MMCA) microparticles and its Au⁰ and Ag⁰ composites retained 48.21±5.34 mg/g, 49.36±6.95 mg/g and 23.95±6.45 mg/g ceftriaxone sodium, respectively, while they retained 79.15±6.85 mg/g, 47.49±6.24 mg/g and 57.47±9.48 mg/g RNA, respectively. Release studies revealed that the presence of Au⁰ and Ag⁰ nanoparticles imparted a slower release behavior to p(CTP‐co‐MMCA) microparticles. The release studies revealed that the presence of Au⁰ and Ag⁰ nanoparticles imparted a slower release behavior to the p(CTP‐co‐MMCA) microparticles.

View access options