Erin X. Wei’s research while affiliated with University of Nebraska Medical Center and other places

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Publications (75)


Analysis of current dermatopathology training across U.S. residency programs
  • Article

April 2025

Archives of Dermatological Research

Evelyn F. Fagan

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Joseph T. McGrath

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Erin X. Wei

Dermatopathology (DP) is integral to dermatology residency training, aiding in accurate diagnoses and clinical interpretations. This study evaluates the current state of DP education and faculty backgrounds in dermatology residency programs, using information available on 142 ACGME-accredited dermatology residency programs. The focus was on DP training, including dedicated rotations, training years, and duration as well as DP faculty and fellowship opportunities. Of the programs analyzed, 53.52% offered distinct DP rotations. Residents in these programs spent an average of 11.37 weeks in DP training, with 70.83% providing DP exposure in the first year. The average number of board-certified dermatopathologists per program was 2.91 (SD = 2.11); however, 23.19% of programs lacked dermatology-trained dermatopathologists. DP fellowships were available in 36.62% of programs and among fellowship directors, 63.46% were board-certified in anatomic pathology and 51.98% in dermatology. While DP training is widely offered, the extent and structure of this training vary across residency programs with many lacking dedicated rotations or first-year exposure. Both dermatology-trained and pathology-trained dermatopathologists contribute to academic settings, although fellowship directors are more commonly trained in pathology. This highlights the need for greater consistency and clarity in DP training across residency programs to ensure comprehensive exposure in this essential field.



Bibliometric Analysis of the 50 Most Cited Publications in Epidermolysis Bullosa

April 2025

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4 Reads

Pediatric Dermatology

Epidermolysis bullosa (EB) is a group of inherited skin disorders characterized by extreme skin fragility, leading to recurrent blistering and significant impacts on patients' quality of life. A bibliometric analysis of the 50 most‐cited EB articles from the past six decades reveals that the majority of research focuses on understanding EB pathogenesis, with a growing emphasis on therapeutic interventions, particularly gene and cell‐based therapies. This study highlights a shift toward clinical trials in recent years, but there is still a need for more global collaboration to address regional variations in EB and improve treatment outcomes for patients worldwide.


Multi-Institutional Study Evaluating the Efficacy of SPOTS (Sun Protection Outreach Teaching by Students), a Skin Cancer Prevention Educational Program for Adolescents
  • Article
  • Full-text available

March 2025

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13 Reads

Dermatologic Surgery

BACKGROUND The Sun Protection Outreach Teaching by Students (SPOTS) program previously demonstrated benefits to adolescents and medical students in the Midwest. Six years later, there have been significant program enhancements and geographic outreach has expanded. OBJECTIVE This multi-institutional program evaluation study sought to quantify the efficacy of the enhanced SPOTS program in improving skin cancer knowledge, sun-safe attitudes, and sun protection behaviors in adolescents living in multiple geographic regions of the United States. MATERIALS AND METHODS Surveys assessing students' knowledge, attitudes, and behaviors concerning skin cancer and sun protection were administered before and 1 month after SPOTS teaching. RESULTS Analysis of 1,508 pre-program and 969 post-program surveys revealed statistically significant improvements in adolescents' knowledge, attitudes, and behaviors regarding sun protection. Notably, there was a 34.3%, 107.5%, and 27.1% relative improvement in the percentage of students' sunscreen protection factor knowledge, belief that a tan is unhealthy, and intention to wear sunscreen, respectively ( p < .001). In addition, 57.6% of students reported having tried to increase sunscreen usage after SPOTS. Subgroup analyses demonstrated similar improvements across Fitzpatrick skin-types and across different geographic regions. CONCLUSION The enhanced SPOTS program demonstrated significant improvements in adolescents' knowledge, attitudes, and behaviors toward sun protection.

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a Patient Race/Ethnicity Represented in SOC Articles in Cosmetic Journals. b Region of Origin Represented in SOC Articles in Cosmetic Journals
Distribution of publications regarding cosmetic dermatology interventions by geographical location
Skin of color representation in cosmetic dermatology literature, 2018–2023

February 2025

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27 Reads

Archives of Dermatological Research

Growing racial diversity raises concerns about equitable dermatology care. Only 4.5% of US medical textbooks include diverse skin types, and dermatologic literature lacks focus on Skin of Color (SOC). This study examines SOC cosmetic research in five dermatology journals. Articles from Lasers in Surgery and Medicine, Journal of Cosmetic Dermatology, Cosmetics, Lasers in Medical Science, and Clinical, Cosmetic, and Investigational Dermatology (September 2018 – September 2023) were screened for cosmetic interventions on SOC, defined as studies with > 50% non-Caucasian patients. Studies without defined race or Fitzpatrick skin type (FST) were excluded. Article type, race, ethnicity, research country, and FST were recorded. Of 5,175 screened articles, 561 (10.84%) met inclusion criteria, and 214 (4.14%) provided FST data. FST 3 (40.74%) and 4 (40.53%) were most represented. East Asian (57.75%) and Middle Eastern-North African (24.06%) ethnicities were most represented, with most research from East Asia (56.15%). SOC articles often lacked specific FST details, focusing on hair issues and came mostly from predominantly Caucasian countries. There is significant underrepresentation of SOC in cosmetic dermatology research, with bias toward FSTs 3, 4 and East Asian populations. This highlights the need for standardized ethnicity reporting and inclusive research to ensure equitable dermatologic care.





Citations (19)


... We found 20 articles (Tables 1, 2) evaluating the role of MMS in melanoma treatment and survival: 19 retrospective cohort studies [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] and 1 meta-analysis [30]. [14] in a large retrospective study (n = 132,726) found no significant difference in 5-year OS between the two procedures. ...

Reference:

Mohs Micrographic Surgery and Improved Survival in Skin Cancer: A Narrative Review
Reduced Disease-Specific Mortality in Melanoma in situ Patients Treated with Mohs Surgery over Wide Local Excision: A Study of the Surveillance, Epidemiology, and End Results Database

Journal of the American Academy of Dermatology

... JAKs phosphorylate and activate cell transcription, which modulates intracellular processes, including genetic expression. Nowadays, JAK inhibitors are among the best treatment options for severe AD due to their effectiveness and safety [2,[72][73][74]. Based on real-life data results, they provide rapid improvement in AD symptoms (especially itching), leading to an improved patient quality of life. ...

Analysis of patient experiences regarding JAK inhibitors for atopic dermatitis, psoriasis, alopecia areata, and vitiligo

Archives of Dermatological Research

... These patients were found to have a 15-fold increase of venous thromboembolism risk during the acute phase of disease [120]. Furthermore, this risk was found to be proportional to disease severity while also being heightened by concomitant risk factors [120], which has been corroborated exvivo in unpublished work by our group where we have found that disease severity in BP correlates with functional hypercoagulability on thromboelastography and increased clot resistance to tPA-mediated lysis secondary to increased PAI-1 activity [121]. Another cohort study involving 2,654 patients with BP compared to 26,814 comparator patients found that after propensity scorematching for 60 venous thromboembolism risk factors and severity markers, BP patients had a 2-fold greater risk of VTE [117]. ...

Resistance to tPA-induced Fibrinolysis and Activation of Coagulation is Present in Autoimmune Bullous Diseases of the Skin
  • Citing Article
  • September 2024

Journal of Thrombosis and Haemostasis

... We found 20 articles (Tables 1, 2) evaluating the role of MMS in melanoma treatment and survival: 19 retrospective cohort studies [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] and 1 meta-analysis [30]. [14] in a large retrospective study (n = 132,726) found no significant difference in 5-year OS between the two procedures. ...

Improved disease-specific survival in head and neck cutaneous melanomas treated with Mohs surgery over wide local excision in the United States

Journal of the American Academy of Dermatology

... Potential explanations include the higher levels of stress, social isolation, and lack of support that unmarried individuals were likely to experience, which might contribute to lower survival rates for cancer patients. This was consistent with existing research findings (46,47). ...

Influence of Marital Status on Stage at Presentation and Disease-Specific Survival in Sebaceous Carcinoma: An Analysis of the Surveillance, Epidemiology, and End Results Database

Journal of the American Academy of Dermatology

... Patients with skin of color (SOC) experience unique challenges in receiving dermatologic care, with prior research demonstrating fewer reimbursable work relative value units for non-White patients [1]. SOC patients have been shown to prefer specialty clinics with expertise and clinical focus in treating darker skin tones, [2] and Skin of Color clinics (SOC-C) are growing in popularity among academic dermatology, currently among the top 15 most frequently offered in residency programs [3]. This study seeks to investigate the value of a SOC-C through both patient demographics and clinic utilization metrics. ...

A Cross-sectional Analysis of Specialty Clinics and Subspecialty Training Among Dermatology Programs
  • Citing Article
  • May 2024

Journal of the American Academy of Dermatology

... J. Johnson et al., 2024). The ever-changing market conditions require companies to adapt and know how to interact with target consumers so that the products and services offered can compete (Evans et al., 2024;Ituarte et al., 2024). PT Pos Indonesia Sragen Branch, which operates in the expedition and financial services sector, faces challenges in increasing public awareness of its products and services (Phillips et al., 2024;Shabahang et al., 2024). ...

A cross‐sectional analysis of social media searches for popular hidradenitis suppurativa treatments using Facebook, Reddit, and Google Trends
  • Citing Article
  • March 2024

... 22 This disease process frequently results in discontinuation of ICI therapy, as well as the use of systemic immunosuppressants, 41 although early diagnosis and targeted management can allow for continued ICI therapy in appropriate cases. 42 ICI-BP cases tend to be more delayed in presentation than typical drug-induced BP, can manifest after a rash-free pruritic prodrome, may be 'non-bullous' with eczematous/urticarial plaques, or may present with bullae and other morphologies (eg, eczematous eruptions). 41 These eruptions are important as they may have implications for tumor response and potentially survival. ...

Impact of Biologic Therapy on Cancer Outcomes in Patients with Immune Checkpoint Inhibitor-Induced Bullous Pemphigoid
  • Citing Article
  • June 2022

Journal of the American Academy of Dermatology

... The association of BP with response was confirmed on a larger cohort of 35 patients, where risk factors for disease development were also studied using a multivariate logistic regression model.16 Risk factors for the development of ICI-BP included age > 70 (OR, ...

Risk Factors for the Development of Bullous Pemphigoid in US Patients Receiving Immune Checkpoint Inhibitors
  • Citing Article
  • April 2022

JAMA Dermatology

... 79 Following this recognition, they generate superoxide free radicals via respiratory bursts that are facilitated by nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. 80 These superoxide radicals are subsequently converted into hydrogen peroxide and other cytotoxic reactive oxygen species (ROS), which are released within intracellular phagosomes or onto extracellular plasma membranes. 80 Neutrophils also contain a distinct pool of granules that can release various antimicrobial proteins to eliminate pathogens. ...

An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils
  • Citing Article
  • March 2022

Journal of Molecular Biology