Eric Therasse's research while affiliated with Centre hospitalier de l'Université de Montréal (CHUM) and other places

Publications (147)

Article
Introduction There is a growing need for small-diameter (<6 mm) off-the-shelf synthetic vascular conduits for different surgical bypass procedures, with actual synthetic conduits showing unacceptable thrombosis rates. The goal of this study was to build vascular grafts with better compliance than standard synthetic conduits and with an inner layer...
Article
Full-text available
Background Preparation of patients with iodine contrast media (ICM) allergy who require adrenal vein sampling (AVS) to establish source of aldosterone excess in confirmed primary aldosteronism (PA) is controversial. Usual premedication with high dose prednisone can interfere with cortisol determinations, possibly altering the aldosterone-to-cortiso...
Article
Full-text available
Background Preparation of patients with iodine contrast media (ICM) allergy who require adrenal vein sampling (AVS) to establish source of aldosterone excess of their confirmed primary aldosteronism (PA) is controversial. Usual premedication with high dose prednisone can interfere with cortisol determinations, possibly altering the aldosterone-to-c...
Article
Purpose To compare the mechanical properties of aneurysm content after endoleak embolization with a chitosan hydrogel (CH) versus a chitosan hydrogel with sodium tetradecyl sulphate (CH-STS) using strain ultrasound elastography (SUE). Materials and Methods Bilateral common iliac artery type Ia endoleaks were created in nine dogs. Per animal, one e...
Article
Full-text available
Purpose: To describe the interventional management and clinical outcome of pancreatico-duodenal arterio-venous malformations (PDAVMs). Material and methods: Seven patients presenting a PDAVM (6 women, 1 male; mean age: 61) were retrospectively reviewed. Technical, clinical success and complications of embolization and surgical management of symp...
Article
Full-text available
Introduction Since the 1990s, endovascular aortic aneurysm repair (EVAR) has become a common alternative to open surgery for the treatment of abdominal aortic aneurysms (AAAs). To aid the deployment of stent-grafts, fluoroscopic image guidance can be enhanced using pre-operative simulation and intraoperative image fusion techniques. However, the im...
Article
Purpose: This study aimed to demonstrate the efficacy and safety of the SoundBite® Crossing System‒Peripheral (SCS‒P) to facilitate crossing chronic total occlusions (CTOs) of infrainguinal arteries. Failure to cross CTOs is the main cause of failed endovascular revascularization attempts. The SCS‒P is a newly developed device that uses a 0.018-in...
Preprint
Full-text available
PurposeTo describe the interventional management and clinical outcome of pancreatico-duodenal arterio-venous malformations (PDAVMs).Material and Methods Seven patients presenting a PDAVM (6 women, 1 male; mean age: 61) were retrospectively reviewed. Technical, clinical success and complications of embolization and surgical management of symptomatic...
Article
Purpose To assess whether angioplasty of hemodialysis access (HA) stenosis with a drug-coated balloon (DCB) would prevent restenosis in comparison with plain-balloon percutaneous transluminal angioplasty (PTA). Materials and Methods This prospective randomized clinical trial enrolled 120 patients with dysfunctional arteriovenous fistulae (n = 109)...
Article
Background Adrenal venous sampling (AVS) failure is mainly due to right adrenal vein unavailability. Multinomial regression modeling (MRM) and left adrenal to peripheral vein ratio (LAV/PV) were proposed to predict the lateralization index without the right AVS. Objective To assess external validity MRM and LAV/PV to predict lateralization index w...
Article
Context: Unilateral aldosteronomas should suppress renin and contralateral aldosterone secretion. Complete aldosterone suppression in contralateral adrenal vein sample (AVS) could predict surgical outcomes. Objectives: To retrospectively evaluate the prevalence of basal contralateral suppression using Aldosterone(A) Contralateral(CL) /A Peripheral(...
Article
Full-text available
Background: Adrenal venous sampling (AVS) is performed to distinguish between unilateral or bilateral source of aldosterone in primary aldosteronism (PA). Unilateral aldosteronomas should lead to suppression of renin and contralateral (CL) aldosterone secretion, assessed by the CL suppression ratio. We recently found that CL aldosterone suppression...
Article
Purpose To quantify eye lens dose in interventional radiology and assess whether neck dosimeter is a good surrogate to evaluate eye lens dosimetry. Methods Radiation exposure was prospectively measured in 9 interventional radiologists between May and October 2017. Standard Hp(0,07) thermoluminescent dosimeters (TLDs) were worn at the neck outside...
Article
PurposeTo investigate the feasibility of shear wave sonoelastography (SWS) for endoleak detection and thrombus characterization of abdominal aortic aneurysm (AAA) after endovascular repair (EVAR).Materials and methodsParticipants who underwent EVAR were prospectively recruited between November 2014 and March 2016 and followed until March 2019. Elas...
Article
Purpose: This study evaluated the safety and efficacy of the JETi8 peripheral thrombectomy system in treating acute deep vein thrombosis (DVT). Materials and methods: A retrospective study was conducted in 18 consecutive patients (mean age, 41 years old [range, 15-74 years old]; 5 men and 13 women). There were 21 instances of DVTs (9 iliofemoral...
Article
Context: Previous studies suggested that plasma aldosterone (PAC) response to ACTH stimulation could predict the subtypes of primary aldosteronism (PA) and avoid adrenal venous sampling (AVS). Objective: Assess the usefulness of peripheral (P) PAC response to ACTH stimulation during AVS to identify the source of aldosterone in patients with PA....
Article
Background: AVS identifies aldosterone source in PA from unilateral aldosterone-producing adenoma (APA) or bilateral adrenal hyperplasia (BAH). APA and BAH can overexpress ACTH receptors, but their variable levels may explain discordant lateralization results between basal and post ACTH values (1,2). Previous studies suggested that differential res...
Article
Purpose: To compare automated measurements of maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) orthogonal to luminal or outer wall envelope centerline for endovascular repair (EVAR) follow-up. Material and methods: Eighty-three consecutive patients with AAA treated by EVAR who had at least 1 computed tomography (CT) scan before and 2 C...
Article
Endovascular aneurysm repair is rapidly emerging as the primary preferred method for treating abdominal aortic aneurysm. In this image-guided interventional procedure, to obtain the roadmap and decrease contrast injections, preoperative CT images are overlaid onto live fluoroscopy images using various 2D/3D image fusion techniques. However, the str...
Article
Background: The aim of this study was to examine the safety and efficacy of the SoundBite™ Crossing System for the recanalization of infrainguinal chronic total occlusion (CTO) lesions. CTOs are frequent among patients with severe claudication or critical limb ischemia. Failure to recanalize CTOs remains common and is associated with poor prognosi...
Article
Purpose To evaluate the safety and efficacy of endovascular fiducial markers (EVFMs) for CyberKnife stereotactic radiation therapy (RT) of malignant lung neoplasms in patients with contraindications to percutaneous fiducial marker (PTFM) placement. Materials and Methods Between January 2011 and December 2013, 15 patients (7 men and 8 women) aged 5...
Article
Chronic total occlusion (CTO) lesions are frequent in patients with peripheral and coronary artery disease, and associated with a higher risk of adverse events, including mortality, decreased quality of life, and increased health-care costs. Percutaneous intervention of CTO lesions has been associated with a lower procedural success rate, and curre...
Article
Objective: Many investigators believe basal adrenal venous sampling (AVS) should be done simultaneously while others opt for sequential AVS for simplicity and reduced cost. This study aimed to evaluate concordance of sequential and simultaneous AVS methods. Design and methods: Between 1989 and 2015, bilateral simultaneous sets of basal AVS were...
Article
Objective: Difficulty to recognize or canulate the right adrenal vein is the most frequent cause of adrenal venous sampling (AVS) failure. We aimed to assess multinomial regression modeling (MRM) of peripheral and left adrenal vein samplings to detect lateralization of aldosterone secretion when the right AVS is missing. Methods: Simultaneous bi...
Article
Objectives To investigate if shear wave imaging (SWI) can detect endoleaks and characterize thrombus organization in abdominal aortic aneurysms (AAAs) after endovascular aneurysm repair. Methods Stent grafts (SGs) were implanted in 18 dogs after surgical creation of type I endoleaks (four AAAs), type II endoleaks (13 AAAs) and no endoleaks (one AAA...
Article
Objective: The objective of this study was to evaluate the safety and efficacy of external beam radiation (EBR) in preventing restenosis after superficial femoral artery (SFA) stenting in comparison with a control group treated with SFA stenting only. Methods: In this Institutional Review Board-approved study, patients who provided written infor...
Article
Context: Adrenal vein sampling (AVS) is required to identify a lateralized or bilateral aldosterone source in primary aldosteronism. Objectives: To compare basal and post ACTH selectivity (SR) and lateralization (LR) ratios and to determine the prevalence of basal contralateral suppression and its effect on surgical outcome. Patients and interv...
Article
Purpose: To assess the ability of noninvasive vascular elastography (NIVE) to help characterize endoleaks and thrombus organization in a canine model of abdominal aortic aneurysm after endovascular aneurysm repair with stent-grafts, in comparison with computed tomography (CT) and pathologic examination findings. Materials and methods: All protoc...
Article
Purpose: To evaluate the sensitivity and specificity of non-enhanced chest CT to detect reperfusion after pulmonary arteriovenous malformation (PAVM) embolization. Materials and methods: The Institutional Review Board approved this retrospective HIPAA-compliant study and waived the need for patient consent. All consecutive patients who underwent...
Article
Here we address the automatic segmentation of endovascular devices used in the endovascular repair (EVAR) of abdominal aortic aneurysms (AAA) that deform vascular tissues. Using this approach, the vascular structure is automatically reshaped solving the issue of misregistration observed on 2D/3D image fusion for EVAR guidance. The endovascular devi...
Article
Purpose To assess the sensitivity and specificity for ratios of adrenal vein cortisol level (Ca) to peripheral vein cortisol level (Cp), adrenal vein aldosterone level (Aa) to peripheral vein aldosterone level (Ap), and combined cortisol and aldosterone levels ("combined ratio") for the detection of successful adrenal vein catheterization ("selecti...
Article
To compare the accuracy of C-arm computed tomography (CT) and digital subtraction angiography (DSA) in detecting incomplete stent expansion (ISE) after superficial femoral artery (SFA) stenting using intravascular ultrasound (IVUS) as a gold standard. Fifty patients with symptomatic SFA occlusive disease requiring angioplasty were prospectively inc...
Article
To evaluate the accuracy and source of errors using a two-dimensional (2D)/three-dimensional (3D) fusion road map for endovascular aneurysm repair (EVAR) of abdominal aortic aneurysm. A rigid 2D/3D road map was tested in 16 patients undergoing EVAR. After 3D/3D manual registration of preoperative multidetector computed tomography (CT) and cone beam...
Article
Purpose To assess the impact of contrast injection and stent-graft implantation on feasibility, accuracy, and reproducibility of abdominal aortic aneurysm (AAA) volume and maximal diameter (D-max) measurements using segmentation software. Materials and methods CT images of 80 subjects presenting AAA were divided into four equal groups: with or wit...
Chapter
A persisting blood flow in the aneurysm sac is one of the main concerns of endovascular treatment of aortic aneurysms. The frequency of these endoleaks after EVAR varies from 15 to 50 % [1, 2]. The persisting blood pressure in the aneurysm sac exposes to the risk of rupture [3].
Article
Full-text available
Abdominal aortic aneurysm (AAA) rupture has a high mortality rate. Although the diagnosis of a ruptured AAA is usually straightforward, detection of impending rupture signs can be more challenging. Early diagnosis of impending AAA rupture can be lifesaving. Furthermore, differentiating between impending and complete rupture has important repercussi...
Article
Ischemic syndromes associated with carotid atherosclerotic disease are often related to plaque rupture. The benefit of endarterectomy for high-grade carotid stenosis in symptomatic patients has been established. However, in asymptomatic patients, the benefit of endarterectomy remains equivocal. Current research seeks to risk stratify asymptomatic p...
Article
Full-text available
Many adrenal venous sampling (AVS) protocols require repeated samplings before and after adrenocorticotrophic hormone (ACTH) stimulation. Maintaining catheter selectivity in the adrenal vein over time is essential but can be challenging, especially in the short right adrenal vein, where the catheter is often in an unstable position. The aim of our...
Article
To evaluate venous malformation (VM) volume and contrast-enhancement analysis on magnetic resonance imaging (MRI) compared with diameter evaluation. Baseline MRI was undertaken in 44 patients, 20 of whom were followed by MRI after sclerotherapy. All patients underwent short-tau inversion recovery (STIR) acquisitions and dynamic contrast assessment....
Article
To evaluate the impact of cone-beam computed tomography (CT) during sclerotherapy of low-flow vascular malformations. Eighty-seven cone-beam CT examinations were acquired during 81 sclerotherapy treatments of low-flow malformations in 48 patients: 81 were performed to evaluate sclerosing agent diffusion and six were performed to evaluate needle or...
Article
Full-text available
Purpose. Contrast-induced nephropathy (CIN) can contribute to acute kidney injury (AKI) in patients undergoing endovascular aortic aneurysm surgery. We evaluated the incidence of AKI together with the evolution of early biomarkers of renal injury in patients receiving bicarbonates or NaCl 0.9%. Methods. This study involved endovascular aortic aneur...
Article
The use of computed tomography (CT) and magnetic resonance (MR) imaging has increased tremendously in the past 2 decades. Hence, pregnant and breast-feeding women, although generally healthier than the population at large, are also more likely to require contrast material-enhanced imaging. When a contrast-enhanced CT or MR imaging study is being co...
Chapter
La persistance d’un flux sanguin dans le sac anévrismal constitue l’une des principales préoccupations du traitement endo-vasculaire des anévrismes aortiques. La fréquence de ces endo-fuites varie de 15 jusqu’à 50 % pour l’aorte abdominale [1, 2]. La persistance d’une pression systémique au sein du sac anévrismal expose au risque de rupture de l’an...
Conference Paper
PURPOSE To evaluate the sensitivity and specificity of non-enhanced CT to detect PAVMs reperfusion after embolization. METHOD AND MATERIALS The imaging files of all patients who had pulmonary angiography follow-up after PAVM embolization in our center from 2000 to 2010 were reviewed. PAVM feeding artery, draining vein and aneurismal sac diameters...
Conference Paper
PURPOSE Assessment of adrenal vein catheter selectivity is essential before interpretation of adrenal venous sampling (AVS) which is the gold standard to identify lateralized, surgically curable source of primary aldosteronism. The aim of this study is to evaluate the basal adrenal/peripheral aldosterone (Aa/Ap) ratio to assess AVS selectivity when...
Conference Paper
PURPOSE To compare the reproducibility and accuracy of abdominal aortic aneurysm (AAA) volume measurements on abdominal CT angiography (CTA), using an optimized semi-automated segmentation software, depending if the CTA was injected (C+/C-) and if a stent-graft was implanted (Sg+/Sg-). METHOD AND MATERIALS CTAs of eighty patients presenting AAA we...
Article
To compare different methods measuring abdominal aortic aneurysm (AAA) maximal diameter (Dmax) and its progression on multidetector computed tomography (MDCT) scan. Forty AAA patients with two MDCT scans acquired at different times (baseline and follow-up) were included. Three observers measured AAA diameters by seven different methods: on axial im...
Article
To evaluate the efficacy and safety of percutaneous renal artery embolization (RAE) of iatrogenic vascular kidney injuries and the effects of RAE on renal function and arterial blood pressure (BP). Over a 12-year period, 50 consecutive patients with severe hemorrhage after iatrogenic arterial kidney injuries underwent RAE. Technical success was def...
Article
The recent technological developments of CT and MR units enable fast angiographic acquisitions with an improved spatial and temporal resolution. With advanced 3D visualisation, image post-processing and vessel wall-imaging, these technologies are now almost replacing diagnostic angiography that is now mainly indicated in case of suboptimal computed...
Article
To validate the reproducibility and accuracy of a software dedicated to measure abdominal aortic aneurysm (AAA) diameter, volume and growth over time. A software enabling AAA segmentation, diameter and volume measurement on computed tomography angiography (CTA) was tested. Validation was conducted in 28 patients with an AAA having 2 consecutive CTA...
Article
The purpose of this study was to evaluate the usefulness of renal length, volume, and resistive index measurements at Doppler ultrasound and MR angiography in predicting improvement after renal angioplasty. Fifty-one patients underwent Doppler ultrasound examinations and MR angiography before percutaneous transluminal renal angioplasty. Renal lengt...
Article
To evaluate the ability to create in vivo antegrade fenestrations (IVAF) using a radiofrequency probe in juxtarenal aortic stent-grafts to preserve the patency of renal arteries. Modified stent-grafts with an unsupported fenestration area were deployed in the juxtarenal aorta of 2 25-kg dogs. Prior to deployment, both renal arteries were marked wit...
Article
We developed a hybrid CPU-GPU framework enabling semi-automated segmentation of abdominal aortic aneurysm (AAA) on Computed Tomography Angiography (CTA) examinations. AAA maximal diameter (D-max) and volume measurements and their progression between 2 examinations can be generated by this software improving patient followup. In order to improve the...
Article
To evaluate the safety and effectiveness of Amplatzer vascular plugs (AVPs) for percutaneous closure of arteries feeding pulmonary arteriovenous malformations (PAVMs). Over a 45-month period, 24 consecutive patients with at least one PAVM treated with an AVP were selected from a database on patients with a PAVM who received embolotherapy. Immediate...
Article
To compare the reproducibility and accuracy of abdominal aortic aneurysm (AAA) maximal diameter (D-max) measurements using segmentation software, with manual measurement on double-oblique MPR as a reference standard. The local Ethics Committee approved this study and waived informed consent. Forty patients (33 men, 7 women; mean age, 72 years, rang...
Article
To compare the outcome of patients treated with balloon dilation and stent placement in the management of bronchial strictures after lung transplantation. Forty-one lung recipients were treated with balloon dilation or stent placement between January 1997 and July 2005. Stent placement was reserved for cases of bronchoplasty technical failure or re...
Article
Limited data are available regarding the optimal management of renal artery stenosis (RAS) with a coexisting renal artery aneurysm. We present a case of high-grade RAS treated successfully with a stent-graft deployment resulting in the exclusion of an associated aneurysm. This therapeutic approach induced the sustained normalization of the blood pr...
Article
Objectifs Evaluer la reproductibilité de différentes méthodes de mesure manuelle du diamètre maximal. Valider cliniquement un logiciel mesurant automatiquement la valeur et la progression du diamètre maximal. Matériels et méthodes Etude incluant 40 patients avec AAA (= 4 cm) ayant 2 TDM consécutives (intervalle = 6 mois). Trois observateurs indépe...
Article
Objectifs Connaitre les indications et contraintes anatomiques du traitement endovasculaire de l’AAA. Connaitre les complications du traitement endovasculaire et leur detection en angioscanner. Discuter le role de l’echographie Doppler et de l’IRM comme alternative a l’angioscanner. Points cles La morphologie des arteres iliaques, la qualite du col...
Article
Limited data are available regarding the optimal management of renal artery stenosis (RAS) with a coexisting renal artery aneurysm. We present a case of high-grade RAS treated successfully with a stent-graft deployment resulting in the exclusion of an associated aneurysm. This therapeutic approach induced the sustained normalization of the blood pr...