Emeka Odiaka's research while affiliated with University of Ibadan and other places
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Publications (3)
Purpose
African men are disproportionately affected by prostate cancer (PCa). Given the increasing prevalence of obesity in Africa, and its association with aggressive PCa in other populations, we examined the relationship of overall and central obesity with risks of total and aggressive PCa among African men.
Methods
Between 2016 and 2020, we rec...
Purpose:
Cancer of the prostate (CaP) is the leading cancer among men in sub-Saharan Africa (SSA). A substantial proportion of these men with CaP are diagnosed at late (usually incurable) stages, yet little is known about the etiology of CaP in SSA.
Methods:
We established the Men of African Descent and Carcinoma of the Prostate Network, which i...
Purpose:
Health research in low- and middle-income countries can generate novel scientific knowledge and improve clinical care, fostering population health improvements to prevent premature death. Project management is a critical part of the success of this research, applying knowledge, skills, tools, and techniques to accomplish required goals. H...
Citations
... However, the present observation is consistent with the report by Nattenmueller et al. [25], who found that WHtR was a better predictor of adipose tissue compartments and SMM than BMI and waist-to-hip ratio (WHR), although, compared to the CT-based measurement, WHtR did not adequately capture differences according to age and gender. Nevertheless increased WHtR with different cut-offs is recognized as a risk factor and/or prognostic parameter in numerous clinical conditions, such as thyroid cancer (WHtR ≥ 0.5) [31], primary liver cancer [32,33], prostate cancer (WHtR > 0.59 or ≥ 0.6 [34]), gallbladder cancer [35], breast cancer [1,36], kidney cancer in postmenopausal women [37], all obesity-related cancers (WHtR ≥ 0.51 in men, and ≥ 0.57 in women) [1,38], CRC (WHtR ≥ 0.55 [39] or ≥ 0.5 [40]), and prognosis after CRC surgery [41]. Moreover, increased WHtR is a better predictor for the risk of metabolic disorders (diagnostic value in descending order: WHtR > WHR > WC > BMI) [42]. ...
... The lack of expertise and infrastructure capacity to conduct clinical trials and for data management, as well as the high cost of this type of research, have been pointed out as reasons explaining the disparities in the number of clinical trials worldwide [73]. In response to this, some well-succeeded initiatives for promoting research and networking were implemented in Sub-Saharan Africa, such as the multicentric Men of African descent and Carcinoma of the Prostate (MADCaP) Consortium [74] and the African Esophageal Cancer Consortium (AfrECC) [75]. In a review of randomized, controlled trials on cancer registered on clinicaltrials.gov in November 2022 (N = 93,392 trials), only one took place in Mozambique (ClinicalTrials.gov ...
... Ideally, these resources will follow from the definition and prioritisation of logistical research needs and the ability to support specific types of research. 242,243 These resource and infrastructure elements might therefore include research laboratory space, equipment, and reagents. Many of these resources require consideration of supply chains (eg, for reagents), service contracts (eg, for equipment), as well as training and certification of operators and technicians. ...