Elizabeth Teale's research while affiliated with Bradford Institute for Health Research and other places
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Publications (54)
Aim:
The aim of the study was to reach consensus on modifiable risk factors for a novel system of care to address Manifestations of Frailty in hospitalized older adults.
Design:
Consensus study.
Method:
A modified nominal group technique, incorporating expert group face-to-face interaction, review of existing evidence and pre/post-meeting ques...
Aims
To explore the experiences of older people and ward staff to identify modifiable factors (risk factors) which have the potential to reduce development or exacerbation of manifestations of frailty during hospitalization. To develop a theoretical framework of modifiable risk factors.
Design
Qualitative descriptive study.
Methods
Qualitative in...
Introduction
Medications with Anticholinergic (AC) properties, are prescribed to treat a range of conditions. Older people are increasingly likely to be prescribed multiple AC medications, but are also more likely to experience unwanted adverse effects, such as falls and delirium. The risks of adverse outcomes increase with the number and potency o...
Background:
Delirium is an acute neuropsychological disorder that is common in hospitalised patients. It can be distressing to patients and carers and it is associated with serious adverse outcomes. Treatment options for established delirium are limited and so prevention of delirium is desirable. Non-pharmacological interventions are thought to be...
Introduction
The Community Ageing Research 75+ (CARE75+) study is a longitudinal cohort study collecting extensive health and social data, with a focus on frailty, independence and quality of life in older age. CARE75+ was the first international experimental frailty research cohort designed using trial within cohorts (TwiCs) methodology, aligning...
Background:
Delirium is an acute neuropsychological disorder that is common in hospitalised patients. It can be distressing to patients and carers and it is associated with serious adverse outcomes. Treatment options for established delirium are limited and so prevention of delirium is desirable. Non-pharmacological interventions are thought to be...
Background
Delirium is a distressing, common and serious condition in older people in hospital. Evidence suggests that it could be prevented in about one-third of patients using multicomponent interventions targeting delirium risk factors, but these interventions are not yet routinely available in the NHS.
Objective
The objective was to improve de...
Delirium is an acute neuropsychiatric disturbance secondary to a pathophysiological insult, including illness, injury, or the effects or withdrawal of drugs. Features are variable, and fluctuate, with drowsiness or inattention, change in cognition, and often delusions, hallucinations, emotional, autonomic, and motor disturbance. It is commoner in t...
Objective to provide a preliminary estimate of the effectiveness of the prevention of delirium (POD) system of care in reducing incident delirium in acute hospital wards and gather data for a future definitive randomised controlled trial. Design cluster randomised and controlled feasibility trial. Setting sixteen acute care of older people and orth...
Background
Community hospitals are small hospitals providing local inpatient and outpatient services. National surveys report that inpatient rehabilitation for older people is a core function but there are large differences in key performance measures. We have investigated these variations in community hospital ward performance.
Objectives
(1) To...
Objective:
to provide a preliminary estimate of the effectiveness of the prevention of delirium (POD) system of care in reducing incident delirium in acute hospital wards and gather data for a future definitive randomised controlled trial.
Design:
cluster randomised and controlled feasibility trial.
Setting:
sixteen acute care of older people...
Background
Delirium occurs commonly in older adults and is associated with adverse outcomes. Multicentre clinical trials evaluating interventions to prevent delirium are needed. The Confusion Assessment Method (CAM) is a validated instrument for delirium detection. We hypothesised it would be possible for a large feasibility study to train a large...
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effectiveness of non-pharmacological interventions designed to prevent delirium in hospitalised non-intensive care unit (ICU) patients.
Background: Pain prevalence is higher in older people with frailty compared to fit older people. However, little is known about pain impact on the lives of older people with frailty. Objectives: To investigate pain impact in community dwelling older people (≥75 years) using data from the Community Ageing Research 75+ (CARE75+) cohort study (UKCRN 1...
Introduction
The Community Ageing Research 75+ Study (CARE75+) is a longitudinal cohort study collecting an extensive range of health, social and economic data, with a focus on frailty, independence and quality of life in older age. CARE75+ is the first international experimental frailty research cohort designed using Trial within Cohorts (TwiCs) m...
Background:
the electronic frailty index (eFI) has been developed and validated using routine primary care electronic health record data. The focus of the original big data study was on predictive validity as a form of criterion validation. Convergent validity is a subtype of construct validity and considered a core component of the validity of a...
Background: The electronic frailty index (eFI) has been developed and validated using routine primary care electronic health record data. The focus of the original big data study was on predictive validity as a form of criterion validation. Convergent validity is a subtype of construct validity and considered a core component of the validity of a t...
An increasing number of frail older people are attending emergency departments. Many of these have existing cognitive impairment (e.g. a dementia), whilst for others, there may be an acute confusional state (e.g. delirium). Cognitive impairment is commonly missed in the ED, and this has been associated with poor outcomes. People with frailty and de...
Background
Information on ethnic disparities in stroke between White and Pakistani population in Europe is scarce. Bradford District has the largest proportion of Pakistani people in England; this provides a unique opportunity to study the difference in stroke between the two major ethnic groups.
Aim
To determine the first-ever-stroke incidence an...
Background
Intermediate care (IC) services are a key component of integrated care for elderly people, providing a link between hospital and home through provision of rehabilitation and health and social care. The Patient Reported Experience Measures (PREMs) are designed to measure user experience of care in IC settings.
Objective
To examine the fe...
Background:
care home residents are particularly at risk of delirium due to high prevalence of dementia. The Delirium Observation Screening Scale (DOSS) identifies behavioural changes associated delirium onset that nursing staff are uniquely placed to recognise. We tested the psychometric properties of the DOSS in UK care homes compared with the C...
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To determine the effectiveness of single or multicomponent non-pharmacological interventions in reducing the symptoms, duration or severity of an established episode of delirium in hospitalised people outside intensive care settings.
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To determine the effectiveness of single or multicomponent non-pharmacological interventions in reducing the symptoms, duration or severity of an established episode of delirium in hospitalised people outside intensive care settings. © 2017 The Cochrane Collabor...
Delirium describes a sudden onset change in mental status of fluctuating course. This is a state of altered consciousness characterised chiefly by inattention or lack of arousal, but can also include new impairment of language, perception and behaviour. Certain predisposing factors can make an individual more susceptible to delirium in the face of...
Clinicians who manage delirium must do so without key information required for evidence-based practice, not least lack of any clearly effective treatment for established delirium. Both the nature of delirium and the methods used to research it contribute to difficulties. Delirium is heterogeneous, with respect to motor subtype, aetiology, setting a...
The author would like to apologise for errors in the originally published paper. The following acknowledgement has been added: Hospital Episodes Statistics. Copyright (c) 2016, Re-used with the permission of The Health and Social Care Information Centre. © The Author 2017. Published by Oxford University Press on behalf of the British Geriatrics Soc...
Delirium describes a sudden onset change in mental status of fluctuating course. This is a state of altered consciousness characterised chiefly by inattention or lack of arousal, but can also include new impairment of language, perception and behaviour. Certain predisposing factors can make an individual more susceptible to delirium in the face of...
Introduction
To understand the variation in performance between community hospitals, our objectives are: to measure the relative performance (cost efficiency) of rehabilitation services in community hospitals; to identify the characteristics of community hospital rehabilitation that optimise performance; to investigate the current impact of communi...
Introduction
Delirium is a common and distressing condition associated with frailty, dementia and comorbidity. These are common in long-term care settings. Residents in care homes are therefore at particular risk of delirium. Despite this, methods to detect delirium in care homes are lacking, with existing diagnostic tools taking too long, or requi...
Background:
Delirium is a common mental disorder, which is distressing and has serious adverse outcomes in hospitalised patients. Prevention of delirium is desirable from the perspective of patients and carers, and healthcare providers. It is currently unclear, however, whether interventions for preventing delirium are effective.
Objectives:
To...
Background: frailty is an especially problematic expression of population ageing. International guidelines recommend routine identification of frailty to provide evidence-based treatment, but currently available tools require additional resource.
Objectives: to develop and validate an electronic frailty index (eFI) using routinely available primary...
Multicomponent delirium prevention strategies have been shown in intervention studies consistently to reduce the occurrence of delirium. Based on this convincing evidence base, the National Institute for Health and Care Excellence has advocated the widespread adoption of multicomponent delirium prevention interventions into the routine inpatient ca...
Background:
Delirium is the most frequent complication among older people following hospitalisation. Delirium may be prevented in about one-third of patients using a multicomponent intervention. However, in the United Kingdom, the National Health Service has no routine delirium prevention care systems. We have developed the Prevention of Delirium...
intermediate care (IC) services operate between health and social care and are an essential component of integrated care for older people. Patient Reported Experience Measures (PREMs) offer an objective measure of user experience and a practical way to measure person-centred, integrated care in IC settings.
to describe the development of PREMs suit...
Objective:
to examine the relationship between carphology (aimlessly picking at bedclothes), floccillation (plucking at the air) and delirium in older patients admitted to specialist elderly care wards.
Design:
daily observation for behaviours of carphology and floccillation embedded within a 'before' and 'after' study.
Setting:
three speciali...
An 84 year old woman with a history of postural hypotension and frequent falls presented with a two week history of confusion and wandering. Her general practitioner diagnosed delirium secondary to a urinary tract infection on the basis of a positive urinary dipstick test for white blood cells and nitrites. She failed to improve with oral antibioti...
To investigate the scaling properties of the Subjective Index of Physical and Social Outcome (SIPSO) following stroke in survivors to hospital discharge, unselected by age.
Factor, Mokken and Rasch analyses of the SIPSO using data from a prospective observational cohort study.
Three acute hospitals in Yorkshire, UK PARTICIPANTS: 312 consecutive adm...
Case-mix represents the range of disease severity and baseline characteristics that may be the cause of variation in outcomes between individuals and populations. Adjustment for case-mix is therefore important to allow meaningful comparison of healthcare outcomes. The best available case-mix adjustment model for stroke (the Six Simple Variable [SSV...
Data reporting requirements in many areas of healthcare are considerable, and increasingly form the basis of remuneration. The solution to efficient capture and submission of large volumes of accurate data is therefore likely to be electronic. Using the example of stroke, this article describes the development and implementation of electronic data...
To identify any externally validated prognostic model for predicting outcome in unselected populations following acute stroke comprising variables feasible for collection in routine care.
Searches were run in MEDLINE, EMBASE, CINAHL, PsycInfo, AMED and ISI Web of Science with no limits on publication date or language.
Any study describing the devel...
Collecting outcome measures by patient or proxy-completed postal survey in stroke research offers a pragmatic and cost-effective alternative to interview-based assessments. The psychometric properties of outcome measures cannot be assumed to be equivalent across methods of questionnaire administration. Many stroke outcome measures have variable or...
Citations
... Previous research has characterised hospitalisation as a traumatic event [e.g., 21,22], even resembling interrogation [23], and has recorded that patient-reported hospital experiences are potentially associated with patient outcomes [22,[24][25][26][27]. In fact, regardless of stress, hospitalisation may be damaging for patients (particularly older adults), being a likely risk factor for cognitive decline [28,29], functional decline [30][31][32], decompensated frailty [33], and new iatrogenic disability [34,35]. Therefore, taken together, there is an immediate need for us to improve our understanding of in-hospital stress, and its effects on in-hospital and post-hospital patient outcomes. ...
... Before starting any pharmacological treatment aimed at these disorders, it is necessary to identify and remove the possible causes and triggers of behavioral disorders. Especially in terminally ill patients, there may be physical causes, such as pain, infections, urinary retention, and constipation, which the patient may express with behavioral disturbances, but which instead require an etiological and non-symptomatic treatment [71][72][73]. In advanced-stage dementia, particular attention must be paid to the effects of the environment when staying in new spaces or spaces not recognized by the subject. ...
Reference: COVID-19 and Frailty
... Some studies have shown that more than 83% of these patients are bedridden and only 4% are permitted to stand or walk, which increases the risk of delirium and hinders its resolution once it is established (Covinsky et al., 2003;Brummel et al., 2014;Zisberg et al., 2015;Martínez-Velilla et al., 2016). Multicomponent interventions such as the Hospital Elder Life Program (HELP) have been shown to reduce delirium incidence in the acute care setting by 43%, by acting on modifiable risk factors such as dehydration, pain, sensory impairment, malnutrition, and immobility, compared to usual care (Hshieh et al., 2018;Wang et al., 2020;Burton et al., 2021). ...
... The HELP programme is currently being evaluated in the UK as part of a Prevention of Delirium programme in eight hospitals on geriatric and orthopaedic wards (Young 2009). General medical inpatients aged 65 years and older admitted to an acute medical healthcare setting. ...
... Similar trends have been observed elsewhere. For example, a review of community hospitals in high-income countries describes their role at 'the boundary of primary care, acute hospital care and nursing home care' and as providing 'the full spectrum of service provision from preventative and primary care, to inpatient surgical or medical care' (Winpenny et al., 2016). ...
... Our AKTIVER manual provided explicit parameters for each module. The authors (J.S., C.B., and C.T.) constructed AKTIVER using evidence (Care of Confused Hospitalized Older Persons, 26 Hospital Elderly Life Program, 27 and others 10 ), inspiration from other programs, [28][29][30][31][32][33] and their clinical experience 25 (Table 1). [34][35][36][37][38][39][40][41][42][43] At each site, more than 70% of hospital staff completed a 90-minute basic lesson in delirium detection, management, ...
... More specific and efficient tasks can be chosen for preintervention assessments as they take less time. According to recent guidelines, identification of subjects at risk (Hempenius et al., 2015;Siddiqi et al., 2016) can be helpful for choosing patients for prophylaxis, surveillance, and interventions in connection with surgeries (Baron et al., 2015;Aldecoa et al., 2017;Berger et al., 2018;Burton et al., 2019;Hughes et al., 2020). Hence, the aim of this study was to investigate the association between deficits in specific cognitive domains and reported delirium symptoms in a long-term observation over 8 years. ...
... The digital transformation that has taken place in cardiology has helped to provide a continuum of care in cardiovascular health. Incorporating telemedicine into outpatient settings with a particular focus on risk factor management and implementing rehabilitation activities within the patient's home demonstrated improved patient adherence with outcomes similar to in-person visits [71][72][73]. In addition, remote cardiac care proved to be convenient for both patients and physicians, offering essential advantages such as reduced travel and waiting times, avoidance of unnecessary transfers, reduced costs, less crowding of physicians and patients at hospital centres and flexible schedules (24/7), A. Jordan-Rios et al. ...
... The management of mobility issues in older adults can be challenging due to various factors, including patient-related barriers (e.g., multiple comorbidities) or health care provider-related barriers (e.g., lack of knowledge/training on geriatric syndromes and their clinical management, and limited patient consultation time) (Loganathan et al., 2015;Rastogi and Meek, 2013), leading to unmet health care needs. Older adults, particularly those with frailty, face high burden of pain, but pain management is often sub-optimal, which may worsen mobility and the ability to perform daily activities or participate in social activities (Brown et al., 2019). Among participants with mobility limitations, they expressed that those limitations did not only affect their physical function, but also social and psychological aspects of functioning. ...
... The data reported herein were collected as part of the Community Ageing Research 75 + (CARE75 +) study [16]. The CARE75 + is a longitudinal cohort study conducted in community-dwelling older people living in England aged ≥ 75 years. ...