Elizabeth G. Duke's research while affiliated with North Carolina State College of Veterinary Medicine and other places
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Publications (5)
Chimerism is a widespread phenomenon across the tree of life. It is defined as a multicellular organism composed of cells from other genetically distinct entities. This ability to ‘tolerate’ non-self cells may be linked to susceptibility to diseases like cancer. Here we test whether chimerism is associated with cancers across obligately multicellul...
The ecology in which species live and evolve likely affects their health and vulnerability to diseases including cancer. Using 14,267 necropsy records across 244 vertebrate species, we tested if animals in low productivity habitats, with large habitat range, high body temperature and weight-inferred estimates of metabolic rates, and in high trophic...
This multi-institutional collaborative study of neoplasia in snakes reviewed medical records of snakes at each facility to determine species prevalence, survival, and methods of treatment. Complete species numbers of snakes were also collected at each facility. In total, 65 species, 133 snakes, and 149 unique neoplasias were included in this study....
The Exotic Species Cancer Research Alliance (ESCRA) has been in existence for 5 y. It is an archive of data from zoological, aquarium and
academic institutions into one central location. Through partnerships with over 90 zoos and aquariums we have accumulated over 1,300 cases
of cancer across non-domestic species. Although the accumulation of data...
Citations
... The Exotic Species Cancer Research Alliance (ESCRA) is a neoplasia database established to collect and record neoplasia cases in non-domestic species across facilities, including those not reported in the literature [56,57]. Cases of neoplasia and corresponding treatments are collected from multiple zoological and aquatic institutions, as well as veterinary teaching hospitals and private practices. ...
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... One such analysis reviewed cases from the amphibian neoplasia literature to supplement the Exotic Species Cancer Research Alliance (ESCRA) database. 13 In that analysis, the authors used boosted regression modeling to identify patient, tumor, and management factors associated with positive outcomes in 50 cases. 13 Notably, these cases included 28 different species and 15 different tumor types. ...
