Elizabeth A. Holman's research while affiliated with California Institute of Technology and other places

Publications (5)

Conference Paper
Non-invasive and label-free spectral microscopy (spectromicroscopy) techniques can provide quant. biochem. information complementary to genomic sequencing, transcriptomic profiling, and proteomic analyses. However, spectromicroscopy techniques generate high-dimensional data; acquisition of a single spectral image can range from tens of minutes to h...
Conference Paper
Peptoid bilayer nanosheets are a new class of biocompatible 2D nanomaterial with broad applications, including sensing, membrane mimicry and pathogen binding. They are formed from the self-assembly of sequence-defined peptoid chains and can be readily functionalized to tune their properties. In order to broaden their utility, there is a need to imp...
Article
Full-text available
Non-invasive and label-free spectral microscopy (spectromicroscopy) techniques can provide quantitative biochemical information complementary to genomic sequencing, transcriptomic profiling, and proteomic analyses. However, spectromicroscopy techniques generate high-dimensional data; acquisition of a single spectral image can range from tens of min...
Article
Full-text available
The contribution of planktonic cyanobacteria to burial of organic carbon in deep-sea sediments before the emergence of eukaryotic predators ~1.5 Ga has been considered negligible owing to the slow sinking speed of their small cells. However, global, highly positive excursion in carbon isotope values of inorganic carbonates ~2.22-2.06 Ga implies mas...

Citations

... It is therefore important to understand the forcings for primary productivity in early Earth. Several experimental studies have been conducted to investigate the response of primary productivity to Precambrian conditions, such as high seawater Fe(II), high atmospheric pCO 2 , and unique ecophysiological mechanisms such as competition for nutrients between oxygenic cyanobacteria and Fe(II)-oxidising anoxygenic photosynthesizers (Swanner et al., 2015;Kamennaya et al., 2018;Ozaki et al., 2019;Herrmann et al., 2021;Szeinbaum et al., 2021). Although extant organisms used in the studies described almost certainly cannot be mapped to those present in ecosystems on the early Earth, we can reasonably assume that their core metabolic pathways and ecological activities had equivalents in those early ecosystems (e.g., Falkowski et al., 2008). ...