E Bleuler’s scientific contributions

... Kraepelin's key achievement was linking the pathogenesis and manifestation of mind disorders, differentiating between "dementia praecox" (now known as schizophrenia) as a progressive, biological illness and "manic depression" as an episodic disorder. His distinction between these forms of psychosis has shaped psychiatric understanding for over a century [19] and paved the way for the influential work of Eugen Bleuler, a psychiatrist who later conceptualized "'fundamental anomalies in connections"' in schizophrenia, anticipating today's concepts of functional neural dysconnectivity [20]. ...

Reference:

The Interdisciplinary Synergy Between Neurology and Psychiatry: Advancing Brain Health