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May 2014
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6 Reads
Evidence-Based Practice
Evidence‐Based Answer No. Induction of labor is not indicated for suspected fetal macrosomia, as induction does not decrease associated fetal or maternal morbidity (SOR: A, systematic review of RCTs and cohort trials and Cochrane review). Induction may also increase the cesarean section rate (SOR: C, inconsistent RCTs and retrospective cohort trials).
July 2013
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6 Reads
American Family Physician
December 2012
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8 Reads
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1 Citation
American Family Physician
April 2012
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16 Reads
The Journal of family practice
For most patients with purulent nasal discharge, antibiotics don't decrease symptom duration; they do increase adverse events. Researchers in the field don't recommend using antibiotics as routine treatment for purulent rhinorrhea associated with symptoms of upper respiratory infection.
July 2011
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18 Reads
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2 Citations
The Journal of family practice
Yes. All healthy children without evidence of immunity to varicella who are living in a household with a susceptible pregnant woman should be vaccinated.
June 2009
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49 Reads
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11 Citations
The Journal of family practice
Emollients are effective first-line treatment to decrease symptoms of eczema and reduce the need to use steroids in children. Tar preparations work, but compliance may be limited. Gamma-linoleic acid preparations, borage oil, and evening primrose oil show efficacy in small studies. MAS063DP cream (Atopiclair) is effective. Chamomile and bathing in acidic hot spring water may be effective, but these treatments have not been adequately evaluated. Wet wrap dressings may be effective but increase the risk of skin infections. Hamamelis distillate creams and massage with essential oils/aromatherapy are ineffective.
January 2009
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46 Reads
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2 Citations
The Journal of family practice
Prophylactic oxytocin is fine before or after placental delivery. Timing alone doesn't influence the drug's efficacy in preventing postpartum bleeding (recommendation based on randomized controlled trial and prospective cohort studies).
October 2008
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13 Reads
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3 Citations
The Journal of family practice
They're useful in diagnosing Graves' disease and, to a lesser extent, autoimmune thyroid disease; they can also help predict hypothyroidism. Thyrotropin receptor antibodies (TRAb) may be mildly elevated in a variety of thyroid disorders, but a TRAb level >10 U/L increases the probability of Graves' disease by a moderate to large degree (strength of recommendation [SOR]: cross-sectional study). A positive or negative thyroid peroxidase antibody (TPOAb) test increases or decreases the probability of autoimmune thyroid disease by only a small to moderate degree (SOR: 3 cross-sectional studies). Thyroid-stimulating hormone (TSH) levels >2 mU/L, although still in the normal range, can be followed up with TPOAb testing to determine whether the patient has an increased probability of developing hypothyroidism (SOR: cohort study with a vague hypothyroidism reference standard).
September 2008
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7 Reads
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1 Citation
The Journal of family practice
August 2008
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5 Reads
The Journal of family practice
... 9 Tingginya frekuensi anak yang mengalami angular cheilitis dengan status gizi kurus dan sangat kurus disebabkan karena faktro etiologi utama angular cheilitis pada masa anak-anak ialah defisiensi nutrisi. 4,10,11 1. Responden yang berstatus gizi dibawah normal sebanyak 50 anak. ...
May 2005
The Journal of family practice
... Oxytocin acts quickly and effectively with minimal adverse effects and can be used in all women, which makes it the main interven- tion for reducing PPH and is the first uterotonic drug option (23). The administration of oxytocin during the TSL reduces the risk of PPH by 40% (24). Immediately after fetal delivery, starting intravenous infusion of 20 IU of oxytocin in 500 mL RL and given within 2 hours is the routine protocol in our institute for AMTSL. ...
January 2009
The Journal of family practice
... Antimicrosomal antibody (AMA) or TPOAb are frequently used as a marker of thyroid autoimmunity in GD as they are readily available and inexpensive. However, the value of AMA or TPOAb used in isolation in GD is limited by their poor sensitivity and specificity [9], as illustrated by a normal titre despite severe disease activity in this patient. ...
October 2008
The Journal of family practice
... At the present time, no formal studies investigating arthropathy and fluoroquinolones in adults have been published . Although a full discussion of this subject in the pediatric population is beyond the scope of this review, it is worth noting that multiple studies have examined the association between fluoroquinolones and arthropathy in children by imaging their joints with magnetic resonance imag-ing (MRI)7980818283. MRI findings are somewhat difficult to interpret given the presence of possible confounding factors, but joint effusion and cartilage abnormalities have been re- ported [83,84]. ...
September 2008
The Journal of family practice
... Identification of CAD in women can be a diagnostic challenge because of several factors, including the lower prevalence of obstructive CAD in women younger than 65 years, more atypical manifestations of ischaemic symptoms and more frequent resting ST changes. 2 TMT in women have a relatively low diagnostic yield for CAD compared with men, especially when symptoms are atypical or nonspecific. 3,4 The reported sensitivity and specificity of exercise electrocardiographic testing in symptomatic women vary greatly depending on the study characteristics and range from 31% to 71% and 66% to 86%, respectively. 5 Women tend to have a greater release of catecholamines during exercise, which could potentiate coronary vasospasm and augment the incidence of abnormal exercise results. ...
May 2004
The Journal of family practice
... [13][14][15][16][17][18][19][20][21] gabapentin, an antiepileptic drug, has been proven suitable for preventing CTTH. [22][23][24] The effective dose of gabapentin varies greatly, with some patients needing only 200-300 mg a day whereas others may need 2000 mg or more a day. [25,26] There are also various modalities for trigger points (TrPts) therapy, such as the spray and stretch techniques, ultrasound, manipulative therapy, and inactivate TrPts. ...
November 2004
The Journal of family practice
... 8 Statin use during pregnancy is contraindicated, although there is limited evidence from human studies regarding fetal risk. 9 Numerous human case reports have shown associated congenital anomalies with statin exposure, including vertebral, anal, cardiac, tracheal, esophageal, renal, and limb anomalies. 9 Exposure during the first trimester has also been linked causally with intrauterine fetal growth restriction and fetal demise. ...
February 2006
The Journal of family practice
... Whether an induction of labor is elective for an uncomplicated, full term pregnancy or a pregnancy before 39 weeks gestation, there can be added costs and legal risks (Santana and Meyer 2006). Because an elective induction of labor requires cervical ripening, extra ...
December 2006
The Journal of family practice
... The results showed that the levels of aminotransferases and international normalized ratio (INR) did not differ significantly among these two groups (using 2-way analysis of variance) in 2 days following acetaminophen ingestion, thereby suggesting no increase in liver toxicity of therapeutic doses of acetaminophen in alcoholic patients (24). Based on two Randomized Controlled trials (RCTs) and other studies, patients with stable chronic alcoholic disease can receive acetaminophen up to 4 g for 48 to 72 hours (25). Liver toxicity was reported in 76 patients who had received acetaminophen in nontoxic doses (< 6 g/d), all of whom regularly used alcohol. ...
September 2007
The Journal of family practice
... The small margin of exposure between the doses of genistein that produce demonstrable adverse effects in experimental animal models and in formula-fed babies suggests that the possibility of adverse effects should be considered, but studies in humans are necessary. Johnson et al. (Johnson et al., 2008) and Cederroth et al. (2010) have attested to the general safety of soy use but have emphasized that, in view of the scarcity of long-term studies, exposure at the beginning of life should be cautious. ...
February 2008
American Family Physician
