Domagoj Javor's research while affiliated with Medical University of Vienna and other places

Publications (14)

Article
Full-text available
Purpose To assess the radiation dose reduction capabilities and the image quality of a new C-arm system in comparison to a standard C-arm system. Method Prospective, randomized, IRB approved two-arm trial design. 49 consecutive patients with primary or secondary liver cancer were treated with transarterial chemoembolization (TACE) on two different...
Article
Introduction Computed Tomography is an essential diagnostic tool in the management of COVID-19. Considering the large amount of examinations in high case-load scenarios, an automated tool could facilitate and save critical time in the diagnosis and risk stratification of the disease. Methods A novel deep learning derived machine learning (ML) clas...
Article
Objectives: To evaluate the influence of baseline clinical and morphological parameters on the occurrence of a late stent graft related endoleak (srEL; types 1 and 3) after endovascular aneurysm repair (EVAR). Methods: This is a retrospective case control study of patients who were routinely followed up after EVAR of abdominal aortic aneurysms....
Article
Objective Recently, a potentially useful diagnostic approach based on MR diffusion-tensor-imaging (DTI) was reported for the estimation of putative functional placenta tissue (PFPT), thus providing direct information about placental function. Yet, the relation between reduced PFPT and the phenomenon of brain-sparing remains unclear. This study aime...
Article
Full-text available
Objectives: To assess a single-phase, dual-energy computed tomography (DECT) with a split-bolus technique and reconstruction of virtual non-enhanced images for the detection of endoleaks after endovascular aneurysm repair (EVAR). Methods: Fifty patients referred for routine follow-up post-EVAR CT and a history of at least one post-EVAR follow-up...
Article
Objectives: The hypothesis that paclitaxel-eluting balloon angioplasty provides higher 1-year patency rates in femoropopliteal artery in-stent restenosis compared with standard percutaneous transluminal angioplasty (PTA) was tested. Background: Several trials have demonstrated that paclitaxel-eluting balloon angioplasty reduces late luminal loss...
Article
Full-text available
Background: Diffusion-weighted imaging (DWI) is increasingly used to diagnose renal lesion subtypes. Especially in small renal masses, identification of less aggressive tumor types is of clinical interest, as active surveillance strategies can be applied. Purpose: To evaluate the inter-observer variation and diagnostic efficacy of apparent diffu...
Article
Objective To investigate utility and limitations of 3-Tesla diffusion-weighted (DW) magnetic resonance imaging (MRI) for differentiation of benign versus malignant renal lesions and renal cell carcinoma (RCC) subtypes. Materials and Methods Sixty patients with 71 renal lesions underwent 3 Tesla DW-MRI of the kidney before diagnostic tissue confirm...
Article
To evaluate the diagnostic potential of choline measurements by in vivo magnetic resonance spectroscopy (MR spectroscopy) for diagnosis of renal masses. Twenty-eight patients with 29 renal lesions underwent prospectively preoperative 3 T MR spectroscopy of renal masses before diagnostic tissue confirmation. A respiratory-triggered single-voxel MR s...
Article
Full-text available
Aim: To describe the (18)F-fluorodihydro-xyphenylalanine ((18)F-DOPA), positron emission tomography (PET) and magnetic resonance imaging (MRI) appearance of pheochromocytomas, with a focus on the presence or absence of typical MRI features. Eleven patients with histologically-verified pheochromocytoma [sporadic (n=9), multiple endocrine neoplasia (...
Article
To evaluate the ability of dynamic contrast-enhanced (DCE) 3-T MRI for preoperative differentiation between benign and malignant renal tumors and RCC subtypes. Sixty consecutive patients undergoing preoperative DCE 3-T MRI of the kidney were evaluated in this retrospective IRB-approved evaluation. Fifty-four malignant tumors and 17 benign tumors up...
Article
Objectives: Intrauterine growth restriction (IUGR) is a diagnostic challenge, since ultrasound fetal biometry (UFB) provides only a 50% detection rate for IUGR. This may be attributable to the fact that UFB does not allow a direct evaluation of functional placental tissue. We hypothesized that direct assessment, using magnetic resonance diffusion...

Citations

... While this manuscript highlights procedures performed on Philips's systems exclusively, Gislason-Lee et al. report a similar (48-61%) reduction in patient dose when systems with ClarityIQ software is compared to Siemens Axion Artis x-ray machine. Significant reductions in patient exposure (48-77%) with comparable image quality have also been shown when comparing later generations of imaging technology from Siemen systems [43][44][45]. ...
... The publicly shared online platforms are Kaggle [71][72][73][74], Github [75,76], SIRM [77], Mendeley [78,79], Radiopedia [80], IEEE-Dataport [81], NIH [82], Eurorad [83], wiki-cancerimagingarchive [84,85], Harvard [86], social media (Twitter [87] and Instagram [88]), physionet [89], stanfordmlgroup [90] etc. to open community. While others did not disclose the dataset on a public platform to control the privacy policies of hospitals, research institutes, and patients, they have only used the dataset for experiments [1,36,39,43,91,92]. Each tuple from Table 1 states the data source name, image resolution, imaging mode, type, images with class, URL (address to access the dataset), reference number, and authors using the same dataset. ...
... Many reports have reported morphological differences in AAA between sexes, with lower suitability of neck anatomy in women than in men [8,18,19]. However, the results after EVAR, such as immediate and late complications, sac changes, and mortality, are controversial [8,[18][19][20]. In our series, aortic neck diameters and angulations showed significant differences between sexes, with smaller neck diameters and higher angulations in women. ...
... Details of patient selection and patient characteristics are given in Fig. 1 and Table 1, respectively. A part of the study population was included in a previously described cohorts [15,46]. In contrast to our study, analyses referred on the comparison of stent-graft surface movement in patients with and without a type 2 endoleak, and clinical and morphological parameters for the prediction of late stent-graft related endoleaks, respectively. ...
... Suboptimal in utero substrate supply during pregnancy often results in intrauterine growth restriction (IUGR) and has been associated with a number of foetal adaptations, including restricted growth or hypertrophy and/or dysfunction of organs such as liver [1][2][3][4], kidneys [5][6][7], heart [8][9][10], skeletal muscle [11][12][13] and gut [14,15]. These adaptations may allow the allocation of critical energy resources to mechanisms that support the survival and sparing of heart [16][17][18] and brain [19,20] growth; although there is still an impact on the development of these vital organs. Poor foetal substrate supply can result Joanna Lazniewska and Jack R. T. Darby contributed equally to this study. ...
... The mean ED of 3.7 mSv in our study is lower compared to the range from 4.4 to 9.6 mSv reported in literature studying similar scanner technology and patient cohorts [8,9,14,19]. Some previous studies suggested contrast injection protocols with individually calculated injection volumes or multilevel protocols, e.g., for every increase of 10 kg body weight [8,14,19,24]. Although such multilevel contrast injection protocols potentially allow for reduced and more reliable contrast dosing, they are prone to mistakes in routine clinical practice based on our experience and do not necessarily result in lower iodine doses compared to fixed contrast injection protocols [9,13,14,25]. ...
... p < 0.001) was significantly greater in the FP ISR group. is is supported by the current literature as DCBs are the most extensively investigated treatment device for ISR. Multiple randomized controlled trials display superior patency rates and freedom from target lesion revascularization at 1 year compared to percutaneous transluminal angioplasty (PTA; [16][17][18][19]). According to the 2017 European Society of Cardiology Guidelines, there is a Class IIb recommendation with Level B evidence for the use of DCBs in the treatment of ISR [20]. ...
... Diffusion-weighted imaging (DWI), which is widely adopted in clinical practice, is a diagnostic technology that uses water molecule diffusion motion characteristics for imaging [1][2][3][4]. Without increasing the total scanning time [5], routine MRI sequences have enrolled DWI [6], and currently, DWI is commonly adopted for quantitative and qualitative analyses of organs in the upper abdomen [7]. ...
... Currently, contrast-enhanced CT (CECT) is considered the standard of care for the assessment of solid renal tumors. Post-contrast enhancement and heterogeneity of a renal lesion are associated with malignancy and are used to distinguish between RCC subtypes to some extent, but with limited success [7][8][9][10][11][12][13]. Ultrasound is a non-invasive, widely used and readily available imaging technique offering real-time imaging without ionizing radiation. ...
... Alternatively, the indirect detection of intracellular lipid (since it is considered a biomarker of renal cell carcinoma (RCC)) has been previously tried by an MRI method based on the signal drop in out-of-phase T1-weighted images [15][16][17]. This limitation of MRI can be addressed by implementing MRS, which can directly identify specific fatty acids and other metabolites, such as choline and lactate that can help in differentiating and grading RCC [18][19][20][21][22][23]. Due to the alteration in lipid content within the tumor cells of RCC, differentiation from other histological subtypes could be feasible by detecting intracellular lipid contents. ...