Divyarani Kathad’s research while affiliated with All India Institute of Ayurveda New Delhi and other places

Pituitary adenomas are the most common type of pituitary disorder. They are benign neoplasms that account for 10%–15% of all intracranial masses. Pituitary adenomas are usually nonmalignant, but have a heavy burden on patients and health-care systems. Increased availability of magnetic resonance imaging has led to an increase in incidentally found pituitary lesions and clinically relevant pituitary adenomas. Pituitary adenomas present clinically in three ways: syndromes of hormone hypersecretion or deficiency; neurologic manifestations from mass effect of an expanding gland; or an incidental finding on imaging done for an unrelated issue. Nonfunctioning microadenomas and microprolactinomas in asymptomatic patients do not require immediate treatment. However, a small percentage of these tumors will increase in size or cause new pituitary dysfunction and therefore warrant monitoring. In Ayurveda , it can be correlated with Granthi (tumor). In this case report, a 40-year-old female presented to the outpatient department of Kayachikitsa at Ch. Brahm Prakash Ayurved Charak Sansthan with complaints of severe headache, loss of consciousness over the past year, and double vision persisting for two years. The patient had previously been diagnosed with a pituitary microadenoma. Treatment involved a combination of Pathyadi and Varunadi Kwath , administered as 40 mL on an empty stomach in the morning and evening. Additionally, Kanchnaar Guggulu was prescribed at 500 mg twice daily after meals, Triphala Churna at 5 grams once daily before meals, and Aarogya Vardhini Vati at 250 mg twice daily after meals. Vamana and Virechan Karma are also done, and after that, Takra Dhara and Nasya Karma are also given to the patient. The outcome was assessed on the basis of symptoms and laboratory investigations showed profound results. Therefore, it can be said that these medications are quite successful in treating jaundice.

Crohn’s disease (CD) is segmental, noncontinuous, subacute, or chronic inflammation that can affect any part of the digestive tract from the mouth to the anus, with a predilection for the distal ileum and colon. The incidence of CD is increasing and is now 5–10 per 100,000, with a prevalence of 50–100 per 100,000. A 47-year-old patient presented to the outpatient department of the Department of Kayachikitsa, Ch. Brahm Prakash Ayurved Charak Sansthan, New Delhi, with complaints of spasmodic abdominal pain and passage of mucoid stool with increased frequency of defecation from last 2 months. This case was diagnosed as CD in the colonoscopy report. The patient was treated with Panchkarma procedures and Ayurvedic oral drugs and found satisfactory results with no side effects. Colonoscopy, contrast-enhanced computed tomography enterography, and liver function test were considered objective parameters of assessment. Improvement was assessed on the basis of relief in subjective and objective parameters. After the course of treatment, significant improvement was seen in the grading of subjective parameters and laboratory investigation. This case study illustrates that Ayurvedic medicament can be the choice for treating ailments of the gastrointestinal tract.

A person with insomnia has trouble falling asleep or gets insufficient, poor-quality sleep. They might experience frequent nighttime awakenings with difficulty going back asleep and early morning wakefulness. It is common in older adults, females, students, and people with medical illness. The aim is to analyze and review the published clinical studies conducted on insomnia to assess the effectiveness of Ayurvedic remedies for the management of insomnia. For this review, the literature has been searched using databases such as Medline, PubMed, NLM, Ayush Research Portal, and many others. All randomized controlled trials involving individuals with insomnia, utilizing Ayurvedic herbs either alone or in combination and Panchakarma procedures (processes of detoxifying and purifying the body) with an exposure period of ≥7 days, and with the primary outcome being the improvement in sleep quality, were included. This review includes 16 clinical trials, among them Mansyadi Kwath (decoction made up of Jatamamsi (Nardostachys jatamansi DC), Ashwagandha (Withania somnifera Linn.) and Parsik Yvani (Hyoscyamus niger Linn.), Aswagandha (W. somnifera Linn.), Jatamansi (N. jatamansi DC), Tagar (Valeriana wallichii DC.), Brahmi (Bacopa monnieri Linn.), Gud Pippali Churna ( powder of jaggery and root of Piper longum Linn.), Jatipatri Ksheerpaka ( milk decoction of Myristica fragrans Houtt.) , Insomrid tablet (tablet made up of 5 drugs named Jatamamsi, Ashwagandha, Parsik Yvani (H. niger Linn.), Tagar (Valeriana wallichii DC.) , and Sarpagandha (Rauwolfia serpentina Benth.) and Shirodhara (~slowly and steadily dripping medicated liquids on the forehead) are found effective in the treatments of insomnia according to these studies. This research serves as secondary data for further studies and the medication are described here have the ability to manage insomnia with very minimal or no side effects. These drugs are also cost-effective and nonaddictive.

Ayurveda is a holistic science that emphasizes preserving and promoting the fitness of healthy individuals, besides providing a method for the treatment of diseases. In addition, sufficient infrastructure, human resources, and unique modalities for disease prevention, wellness, and management are available. In present scenario Ayush System is growing day by day with support of government with increase in fundings from INR 691 crore to INR 3050 crore over the last seven years. The Ayush systems can contribute significantly to the One Health approach, which addresses the interconnectedness of human, animal, and environmental health. For this purpose it is need of hour to integrate the Ayush system and other related system to provide the integration of particular areas which can be helpful to fulfil the approach of one health and future perspectives on the role of Ayush in One Health. Ayush system have the he unique principals related to preventive measures, such as daily and seasonal regimens and the use of rejuvenating herbs and Achar rasayanas as well as effective therapeutic interventions for the number of health issues for the contribution in one health. Ayurveda also addresses environmental, animal, and plant health issues and promotes the creation of a healthy ecosystem between humans, animals, and the environment. In addition, Ayush can play a role in addressing zoonotic diseases, noncommunicable diseases, antimicrobial resistance, food safety and health of the elderly, children, and environment. To fully utilize the potential of Ayush in the One Health approach, these systems should be integrated into the healthcare infrastructure and network. Furthermore, initiation of collaborative projects, focused research, training and sensitization of Ayush human resources, and promotion of Ayush‑based lifestyles and practices are some of the critical steps required to be taken.

Typhoid fever is a systemic infection associated with fever that is most often caused by Salmonella typhi , which remains a serious problem in developing countries. Once the bacteria are ingested, it quickly multiplies within the stomach, liver, or gallbladder and finally enters the bloodstream, causing symptoms such as fever and headache. The national incidence of typhoid fever in India is 360 cases/100,000 person-years, with an annual estimate of 4.5 million cases and 8930 deaths, assuming a 0.2% case fatality rate. A 10-year-old girl patient visited our outpatient department with complaints of fatigue, anorexia, malaise, occipital headache, and loose stool. Examination and history lead to the diagnosis of typhoid confirmed by the Widal test and Typhi Dot (Immunoglobulin [Ig] G and IgM). This case was managed with Balachaturbhadra Churna 3 g twice per day with lukewarm water after food and Kumaryasava 5 mL twice a day before food. It was given for 5 weeks, and follow-up period was 15 days with a weekly visit. From the result obtained, it can be concluded that therapy with this Ayurvedic combination of drugs showed significant relief in symptoms after 5 weeks of treatment. Ayurveda can be the choice of the ailment.

Epididymal cysts are collection of fluid in a single sac (unilocular) or more than one (multilocular) as a result of dilatation of efferent epididymal tubules due to tubular obstruction with benign in nature and often bilateral in nature. It involves the development of fluid-filled sacs or cysts within the epididymis, a coiled tube located behind each testicle. An epididymal cyst, also known as a spermatocele that affects the male reproductive system. If it is not treated it may develop to an abscess and probably the destruction of the epididymis which can lead to infertility. In Ayurveda it can be under the heading Kaphaja Granthi. A 27-year-old male patient visited the outpatient department of Kayachikitsha with complaints of bilateral scrotal swelling with itching since six months. Patient was diagnosed on the basis of colour doppler of scrotum and it indicates bilateral epididymis head cyst with minimal fluid seen around left spermatic cord with herniation of omental fat on Valsalva. The patient was treated with classical management of Kapahaja Granthi described in texts, Vaman (medicated emesis), Virechana (therapeutic purgation) and followed by administered Arogyavardhini Vati 2 tablet each of 250mg twice a day in empty stomach, Kanchanara Guggulu two tablet each of 500mg twice a day after food with lukewarm water and Varunadi Kashaya 40ml once a day in morning empty stomach. After this treatment there was no scrotal swelling also the colour doppler study reveals normal colour doppler study with no significant abnormality noted. This case indicates the Ayurveda classical management given in texts can be helps to manage the condition like epidydimal cyst.

Hemolytic jaundice, also known as prehepatic jaundice, is hyperbilirubinemia when the total bilirubin level exceeds 3.0 mg/dL. A 27-year-old male patient with features of jaundice, including yellowish discoloration of the eyes, weakness, fatigue, difficulty in breathing, decreased appetite, irritability, and reddish-yellow discoloration of urine, was managed with Mridu virechana (~mild therapeutic purgation) and Ayurvedic medications, namely. Gomutra haritaki (5 g) with Navayasa loha (500 mg) twice daily. Complete blood count and liver function tests were considered for the diagnostic changes in the clinical features and biomarkers, namely, hemoglobin, total red blood cells, total bilirubin, and indirect bilirubin were considered criteria for the assessment of the outcome of the therapeutic intervention. The total duration of treatment was one month, and follow-up was done for six weeks. No complications or recurrences were noticed during the period. This case report illustrates the utility of Ayurvedic modalities in managing hemolytic jaundice.

The liver abscess is the most frequent visceral abscess caused by a parasite or bacterial infection in low and middle-income countries. A liver abscess can cause fever, chills, night sweats, malaise, nausea or vomiting, right shoulder ache, right upper quadrant pain, cough, dyspnea, anorexia, etc. A 20 years old male patient presented with symptoms of fever, chills, malaise, right shoulder pain, and right upper quadrantpain.The patient was treated with Virechan Karma (therapeutic purgation) followed by oral Ayurvedic medicines such as Varunadi Kwatha, Kanchanar Guggulu, and Aarogyavardhini Vati. Pathyaapathy (wholesome-unwholesome diet) based on Ayurveda perspectives was also advised to the patient. The total duration of the treatment was four months, and follow-up was done for one month. Improvement was assessed based on relief in the symptoms and abdomen USG. Complete relief in all symptoms was noted after completion of the treatment. The USG findings revealed a reduction in hypoechoic lesion to size 5.1*5.1 cm with calcified margins in the right lobe segment VIII of the liver. Any complications or adverse events due to treatment were not observed during the treatment period. This case report demonstrates the effectiveness of Ayurvedic approaches in managing Liver abscesses.

Hypothyroidism is a metabolic disorder resulting from insufficient synthesis of thyroid hormones, which are one of the key factors for the maintenance of metabolism. India has a high prevalence of hypothyroidism, which is about 9.4% subclinical cases, and this is more common in females than males. In Ayurveda classics, the functions of metabolism depend on Agnimandhya (weak digestive fire), mainly Medo Dhatwagni Mandya (decreased metabolic factors located in fat tissues). The normal metabolism of tissues is achieved by the management of Agni . A case of hypothyroidism was treated with bio-cleansing therapy, which included Virechan Karma (therapeutic purgation) along with oral medication Kanchnaar Guggulu with Varunadi Kashaya on an empty stomach. The result was assessed on the basis of the level of thyroid stimulating hormone (TSH) and the improvement in the general condition of the patient. The level of TSH decreases from 64.4 µIU/mL to 2.65 µIU/mL during the duration of six months, with an overall subjective perception of feeling well. The present case study demonstrates that hypothyroidism can be managed by the Ayurveda treatment modality.