Denise Bos's research while affiliated with University of Duisburg-Essen and other places

Publications (21)

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Purpose In uveal melanoma patients, liver metastases can be treated by hepatic artery infusion chemotherapy (HAIC). During this procedure, melphalan or, less frequently, fotemustine is infused into the hepatic artery or the hepatic lobe arteries in regularly repeated interventions to achieve local tumor control. The aim of this study was to investi...
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Background Radiation exposures from computed tomography (CT) in children are inadequately studied. Diagnostic reference levels (DRLs) can help optimise radiation doses. Objective To determine local DRLs for paediatric chest CT performed mainly on modern dual-source, multi-slice CT scanners as a function of patient size. Materials and methods Five...
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Purpose The aim of this study was to determine local diagnostic reference levels (DRLs) during endovascular diagnostics and therapy of carotid-cavernous fistulas (CCF). Methods In a retrospective study design, DRLs, achievable dose (AD) and mean values were assessed for all patients with CCF undergoing diagnostic angiography (I) or embolization (I...
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Purpose This study aims to determine local diagnostic reference levels (DRLs) in the endovascular therapy (EVT) of patients with cranial and spinal dural arteriovenous fistula (dAVF). Methods In a retrospective study design, DRLs and achievable dose (AD) were assessed for all patients with cranial and spinal dAVF undergoing EVT (I) or diagnostic a...
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According to a position paper of the European Commission Initiative on Breast Cancer (ECIBC), DBT is close to being introduced in European breast cancer screening programmes. Our study aimed to examine radiation dose delivered by digital breast tomosynthesis (DBT) and digital mammography (FFDM) in comparison to sole FFDM in a clinical follow-up set...
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Background Lack of standardization in CT protocol choice contributes to radiation dose variation. Purpose To create a framework to assess radiation doses within broad CT categories defined according to body region and clinical imaging indication and to cluster indications according to the dose required for sufficient image quality. Materials and Me...
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The selective intra-arterial nimodipine application for the treatment of cerebral vasospasm (CVS) in patients after spontaneous subarachnoid hemorrhage (sSAH) is widely employed. The purpose of this study is to examine the radiation exposure and to determine local reference levels (RLs) of intra-arterial nimodipine therapy. In a retrospective study...
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The purpose of this study is to examine radiation doses and image quality of a low-dose (LD) protocol for chest and abdomen/pelvis (CAP) CT compared with a standard (STD) protocol. A total of 361 patients were included between October 2019 and April 2020; 104 patients with LD-protocol (100 kV, ref mAs 80 (chest)/145 (abdomen/pelvis)) and 257 patien...
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Ob jectives: The European Society of Radiology identified 10 common indications for computed tomography (CT) as part of the European Study on Clinical Diagnostic Reference Levels (DRLs, EUCLID), to help standardize radiation doses. The objective of this study is to generate DRLs and median doses for these indications using data from the UCSF CT In...
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CT myelography (CTM) is a diagnostic technique for the evaluation of various spinal pathologies, and plays an important role in diagnosis of different diseases such as spontaneous intracranial hypotension and postoperative cerebrospinal fluid leaks. The aims of this study were to examine radiation exposure, establish diagnostic reference levels (DR...
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Cardiac and liver computed tomography (CT) perfusion has not been routinely implemented in the clinic and requires high radiation doses. The purpose of this study is to examine the radiation exposure and technical settings for cardiac and liver CT perfusion scans at different CT scanners. Two cardiac and three liver CT perfusion protocols were exam...
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Purpose Apart from the commonly applied manual needle biopsy, CT-guided percutaneous biopsies of bone lesions can be performed with battery-powered drill biopsy systems. Due to assumably different radiation doses and procedural durations, the aim of this study is to examine radiation exposure and establish local diagnostic reference levels (DRLs) o...
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The aim of this phantom study is to examine radiation doses of dual- and single-energy computed tomography (DECT and SECT) in the chest and upper abdomen for three different multi-slice CT scanners. A total of 34 CT protocols were examined with the phantom N1 LUNGMAN. Four different CT examination types of different anatomic regions were performed...
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Purpose: To assess suspected acute stroke, the computed tomography (CT) protocol contains a non-contrast CT (NCCT), a CT angiography (CTA), and a CT perfusion (CTP). Due to assumably high radiation doses of the complete protocol, the aim of this study is to examine radiation exposure and to establish diagnostic reference levels (DRLs). Methods:...
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Background In the assessment of diseases causing skeletal lesions such as multiple myeloma (MM), whole-body low-dose computed tomography (WBLDCT) is a sensitive diagnostic imaging modality, which has the potential to replace the conventional radiographic survey. Purpose To optimize radiation protection and examine radiation exposure, and effective...
Article
Full-text available
PurposeThis study aims to determine local diagnostic reference levels (LDRLs) of intra-arterial chemotherapy (IAC) procedures of pediatric patients with retinoblastoma (RB) to provide data for establishing diagnostic reference levels (DRLs) in pediatric interventional radiology (IR).Methods In a retrospective study design, LDRLs and achievable dose...

Citations

... In the current monocentric study, detailed dosimetrics in CCF patients treated by fluoroscopically-guided coil embolization are presented and compared between patients with direct and indirect CCFs, as well as between various DSA acquisition protocols. These data might be valuable in order to introduce novel dedicated DRLs, as only a few dosimetry articles specifically dealing with the endovascular treatment of this subtype of intracranial fistulas have been published so far [16]. ...
... CTM in dual-source mode is often preferred, especially in patients with postoperative status and metal implants after osteosynthesis, because it allows better beam hardening artifact suppression [6,20,21]. In the literature, studies on the impact of the dual-source mode on radiation exposure of CT are divergent [22]: our results, like other studies [23][24][25], show a slight dose increase, although in principle a comparable radiation exposure can also be achieved [26,27]. Radiation exposure on the SOMATOM Force was slightly lower in dual-source mode for CTM compared with the study of Grams et al. [6]. ...
... The basilar artery and superior sagittal sinus were selected as the input artery and output vein, respectively. The dose length product (DLP) of a patient was 803.04 mGy·cm (13). ...
... We would like to thank the authors of the "Letter to the Editor" concerning our manuscript "Estimation of radiation exposure of children undergoing superselective intra-arterial chemotherapy for retinoblastoma treatment: Assessment of Local Diagnostic Reference Levels as a function of age, sex and interventional success" [1] for their feedback in this important and exciting field of research. ...