Dayanna Barreto's scientific contributions

Publications (3)

Article
Full-text available
Background: Recent open-label trials show that psychedelics, such as ayahuasca, hold promise as fast-onset antidepressants in treatment-resistant depression. Methods: To test the antidepressant effects of ayahuasca, we conducted a parallel-arm, double-blind randomized placebo-controlled trial in 29 patients with treatment-resistant depression. P...
Preprint
Recent open label trials show that psychedelics, such as ayahuasca, hold promise as fast-onset antidepressants in treatment-resistant depression. In order to further test the antidepressant effects of ayahuasca, we conducted a parallel-arm, double-blind randomized placebo-controlled trial in 29 patients with treatment-resistant depression. Patients...

Citations

... Psychedelic research is currently undergoing a renaissance. Representative compounds have been shown to be powerful, persistent antidepressants in humans [19][20][21][22] , have antidepressant-like effects 13 and to reduce inflammation in rodents 23-25 , and to increase neuroplasticity in larval Drosophila and rodent neuronal cell culture 26 . ...
... Näiden piirteiden katsotaan olevan merkittävä tekijä hoidon vaikuttavuuden kannalta. Joissain kliinisissä kokeissa terapiaa ei kuitenkaan ole käytetty, esimerkiksi brasilialaisessa ayahuascan vaikutusta hoitoresistenttiin masennukseen selvittäneessä 29 potilasta sisältäneessä tutkimuksessa [50]. Siinä tutkijat olivat läsnä viereisessä huoneessa, tarjoten apua vain tarvittaessa. ...