David Neville’s research while affiliated with New York State Psychiatric Institute and other places

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Publications (5)


Uncomplicated and Comorbid Obsessive-Compulsive Disorder in an Epidemiologic Sample
  • Article

May 1998

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15 Reads

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98 Citations

CNS spectrums

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Steven Greenwald

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David Neville

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[...]

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Myrna M. Weissman

This study investigates lifetime prevalence rates, demographic characteristics, childhood conduct disorder and adult antisocial features, suicide attempts, and cognitive impairment in individuals with obsessive-compulsive disorder (OCD) uncomplicated by or comorbid with any other psychiatric disorder. The data are from the NIMH Epidemiological Catchment Area (ECA) study, and the current analyses compared subjects with uncomplicated OCD (no history of any other lifetime psychiatric disorder) comorbid OCD (with any other lifetime disorder), other lifetime psychiatric disorders, and no lifetime psychiatric disorders across these variables. OCD in its uncomplicated and comorbid form had significantly higher rates of childhood conduct symptoms, adult antisocial personality disorder problems, and of suicide attempts than did no or other disorders. Comorbid OCD subjects had higher rates of mild cognitive impairment on the Mini-Mental Status Exam than did subjects with other disorders. These findings suggest that a subgroup of OCD patients may have impulsive features, including childhood conduct disorder symptoms and an increased rate of suicide attempts; wider clinical attention to these outcomes is needed.


Uncomplicated and comorbid obsesive-compulsive disorder in an epidemiologic sample

January 1996

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35 Reads

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116 Citations

This study investigated lifetime prevalence rates, demographic characteristics, childhood conduct disorder and adult antisocial features, suicide attempts, and cognitive impairment in individuals with obsessive-compulsive disorder (OCD) uncomplicated by or comorbid with any other psychiatric disorder. The data are from the NIMH Epidemiologic Catchment Area (ECA) study, and the current analyses compared subjects with uncomplicated OCD (no history of any other lifetime psychiatric disorder), comorbid OCD (with any other lifetime disorder), other lifetime psychiatric disorders, and no lifetime psychiatric disorders across these variables. OCD in its uncomplicated and comorbid form had significantly higher rates of childhood conduct symptoms, adult antisocial personality disorder problems, and of suicide attempts than did no or other disorders. Comorbid OCD subjects had higher rates of mild cognitive impairment on the Mini-Mental Status Exam than did subjects with other disorders. These findings suggest that a subgroup of OCD patients may have impulsive features, including childhood conduct disorder symptoms and an increased rate of suicide attempts; wider clinical attention to these outcomes is needed.


Body Dysmorphic Disorder Diagnostic Issues and Related Disorders

February 1992

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19 Reads

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55 Citations

Psychosomatics

This article reviews diagnostic issues about body dysmorphic disorder and discusses its relationship to other disorders. Diagnostic and symptomatic overlap with obsessive-compulsive disorder is explored; associated features, course of illness, presumed etiology, and treatment outcome are compared; and similarities and differences are reviewed. Other illnesses with similar features, such as anorexia nervosa, social phobia, and the disorders associated with cosmetic surgery are mentioned. These findings are discussed in light of the development of DSM-IV diagnostic criteria.



Neurological and structural involvement in OCD

January 1990

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8 Reads

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4 Citations

Neuropsychiatry, Neuropsychology, and Behavioral Neurology

Comments on the study of C. L. Hamlin et al (see record 1990-31104-001), in which an obsessive-compulsive disorder (OCD) patient was examined using single-photon-emission computed tomography (CT). An asymmetrical decrease in right striatal and right temporal N-isopropyl-p-[–1–2–3I] iodoamphetamine deposition was found while the S was extensively symptomatic. (PsycINFO Database Record (c) 2012 APA, all rights reserved)

Citations (4)


... The diagnosis of OCD usually occurs in adulthood, but numerous studies have shown how OCD develops starting from childhood and adolescence [25,26]. Although most clinical studies on OCD have concentrated on full-blown presentations, studies have shown that OCD can also manifest in a milder subsyndromal form, as with many other psychiatric disorders [27,28] that seem particularly frequent among specific groups of individuals, such as patients with ASD [23,27,[29][30][31][32][33][34]. In this context, the link between ASD and OCD has been vastly investigated and documented. ...

Reference:

Obsessive–Compulsive Traits and Problematic Internet Use Are Increased Among Adults with Autism Spectrum Disorder: Is There a Role of Obsessive Doubts and Communication Impairment?
Uncomplicated and Comorbid Obsessive-Compulsive Disorder in an Epidemiologic Sample
  • Citing Article
  • May 1998

CNS spectrums

... Perhaps enforcing this argument for further research among pediatric populations, Flessner et al. (2010) indicated a worrisome interaction between existing cognitive dysfunction and treatment outcomes in a pediatric sample, specifying that worse executive functioning may impede the benefits of treatment. Other authors have suggested similar deleterious associations between cognitive deficits and treatment in both adults (Hollander et al., 1990) and children (March et al., 1990) while yet others have not found such a relationship Swedo et al., 1990). Andres et al. (2008) conducted the first study to investigate the stability of neuropsychological deficits in children and adolescents following treatment for OCD. ...

Neurological and structural involvement in OCD
  • Citing Article
  • January 1990

Neuropsychiatry, Neuropsychology, and Behavioral Neurology

... Większość ankietowanych przyznała, że kompleksy dotyczą kilku części ciała jednocześnie. Liczne badania wskazują, że mężczyźni chorzy na BDD częściej skupiają się na genitaliach i gęstości owłosienia na głowie, zaś kobiety na biodrach, piersiach, nogach i nadmiernym owłosieniu ciała [7]. W niniejszym badaniu, bez podziału na płeć, z konkretnie wskazanych części ciała dominowały piersi, oczy, usta i nos. ...

Body Dysmorphic Disorder Diagnostic Issues and Related Disorders
  • Citing Article
  • February 1992

Psychosomatics

... In the present study, the mean untreated duration of OCD was 7.1 years, which closely corresponded to the 7 years reported by previous studies [70]; however, the period may be as long as 17 years [71]. The prevalence of OCD in the general population is reportedly as high as 1.1-1.8% ...

Uncomplicated and comorbid obsesive-compulsive disorder in an epidemiologic sample
  • Citing Article
  • January 1996