David Moher's research while affiliated with Ottawa Hospital Research Institute and other places

Publications (983)

Article
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Background The application of artificial intelligence (AI) in healthcare is an area of immense interest. The high profile of ‘AI in health’ means that there are unusually strong drivers to accelerate the introduction and implementation of innovative AI interventions, which may not be supported by the available evidence, and for which the usual syst...
Article
Background: Protocols are an essential document for conducting randomised controlled trials (RCTs). However, the completeness of the information provided is often inadequate. To help improve the content of trial protocols, an international group of stakeholders published the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT...
Article
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Background: Literature searches underlie the foundations of systematic reviews and related review types. Yet, the literature searching component of systematic reviews and related review types is often poorly reported. Guidance for literature search reporting has been diverse and, in many cases, does not offer enough detail to authors who need more...
Article
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The extent to which a retraction might require revising previous scientific estimates and beliefs – which we define as the epistemic cost - is unknown. We collected a sample of 229 meta-analyses published between 2013 and 2016 that had cited a retracted study, assessed whether this study was included in the meta-analytic estimate and, if so, re-cal...
Article
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Importance Extenuating circumstances can trigger unplanned changes to randomized trials and introduce methodological, ethical, feasibility, and analytical challenges that can potentially compromise the validity of findings. Numerous randomized trials have required changes in response to the COVID-19 pandemic, but guidance for reporting such modific...
Preprint
Background: Problems continue to exist with the reporting of and risk of bias in search methods and strategies in systematic reviews and related review types. Peer reviewers who are not familiar with what is required to transparently and fully report a search may not be prepared to review the search components of systematic reviews, nor may they kn...
Article
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Plain English summary In academia, authorship on a research publication is a central means to obtain credit for one’s contribution to a research project. In order to guide authorship decision making and facilitate transparent processes, the International Committee of Medical Journal Editors (ICMJE) has produced recommendations for authorship. These...
Article
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Background Data-sharing policies in randomized clinical trials (RCTs) should have an evaluation component. The main objective of this case–control study was to assess the impact of published re-uses of RCT data in terms of media attention (Altmetric) and citation rates. Methods Re-uses of RCT data published up to December 2019 (cases) were searche...
Article
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Introduction Standards for Reporting of Diagnostic Accuracy Study (STARD) was developed to improve the completeness and transparency of reporting in studies investigating diagnostic test accuracy. However, its current form, STARD 2015 does not address the issues and challenges raised by artificial intelligence (AI)-centred interventions. As such, w...
Article
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Objectives This randomized controlled trial aimed to test whether women or men would be preferred with identical curriculum vitae (CV); and the impact of the career stage in the evaluators’ choice. Study Design and Setting A simulated post-doctoral process was carried forward to be assessed for judgment. Level 1 and 2 Brazilian fellow researchers...
Article
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Since the early 1990s, ecologists and evolutionary biologists have aggregated primary research using meta-analytic methods to understand ecological and evolutionary phenomena. Meta-analyses can resolve long-standing disputes, dispel spurious claims, and generate new research questions. At their worst, however, meta-analysis publications are wolves...
Article
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In an effort to better utilize published evidence obtained from animal experiments, systematic reviews of preclinical studies are increasingly more common-along with the methods and tools to appraise them (e.g., SYstematic Review Center for Laboratory animal Experimentation [SYRCLE's] risk of bias tool). We performed a cross-sectional study of a sa...
Article
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Objective : To assess the reporting quality of randomised controlled trials (RCTs) with multicentre design, particularly whether necessary information related to multicentre characteristics was adequately reported. Study Design and Setting : Through a search of 4 international electronic databases, we identified multicentre RCTs published in Engli...
Article
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Randomised controlled trials are increasingly conducted as embedded, nested, or using cohorts or routinely collected data, including registries, electronic health records, and administrative databases, to assess if participants are eligible for the trial and to facilitate recruitment, to deliver an embedded intervention, to collect trial outcome da...
Article
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In this response to Labib and Evans, authors of the Hong Kong Principles look forward to collaborating with those from the broad research integrity community to ensure that issues of equity, diversity and inclusion will become part of the ecosystem of research integrity.
Article
Objective: To explore the impact of the Annals of Internal Medicine (AIM) data-sharing policy for randomized controlled trials (RCTs) in terms of output from data-sharing (i.e. publications re-using the data). Study design and setting: Retrospective study. RCTs published in the AIM between 2007 and 2017 were retrieved on PubMed. Publications whe...
Article
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Many randomized controlled trials (RCTs) are biased and difficult to reproduce due to methodological flaws and poor reporting. There is increasing attention for responsible research practices and implementation of reporting guidelines, but whether these efforts have improved the methodological quality of RCTs (e.g., lower risk of bias) is unknown....
Article
Background: Funded health research is being published in journals that many regard as “predatory”, deceptive, and non-credible. We do not currently know whether funders provide guidance on how to select a journal in which to publish funded health research. Methods: We identified the largest 46 philanthropic, public, development assistance, public-p...
Article
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Background Investigations of transparency, reproducibility and replicability in science have been directed largely at individual studies. It is just as critical to explore these issues in syntheses of studies, such as systematic reviews, given their influence on decision-making and future research. We aim to explore various aspects relating to the...
Article
Objectives Data sharing practices remain elusive in biomedicine. The COVID-19 pandemic has highlighted the problems associated with the lack of data sharing. The objective of this article is to draw attention to the problem and possible ways to address it. Study Design and Setting This article examines some of the current open access and data shar...
Article
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Objectives Randomised controlled trials conducted using cohorts and routinely collected data, including registries, electronic health records and administrative databases, are increasingly used in healthcare intervention research. A Consolidated Standards of Reporting Trials (CONSORT) statement extension for trials conducted using cohorts and routi...
Article
During the COVID-19 pandemic, the rush to scientific and political judgements on the merits of hydroxychloroquine was fuelled by dubious papers which may have been published because the authors were not independent from the practices of the journals in which they appeared. This example leads us to consider a new type of illegitimate publishing enti...
Article
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The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess the trustworthiness and applicability of the review findings. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement was developed to facilitate transparent and complete reporting of systematic reviews an...
Article
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The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update t...
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Matthew Page and co-authors describe PRISMA 2020, an updated reporting guideline for systematic reviews and meta-analyses.
Article
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For many users of the biomedical literature, abstracts may be the only source of information about a study. Hence, abstracts should allow readers to evaluate the objectives, key design features, and main results of the study. Several evaluations have shown deficiencies in the reporting of journal and conference abstracts across study designs and re...
Article
The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update t...
Article
Full-text available
The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did, and what they found. Over the past decade, advances in systematic review methodology and terminology have necessitated an update t...
Article
Importance Convalescent plasma is a proposed treatment for COVID-19. Objective To assess clinical outcomes with convalescent plasma treatment vs placebo or standard of care in peer-reviewed and preprint publications or press releases of randomized clinical trials (RCTs). Data Sources PubMed, the Cochrane COVID-19 trial registry, and the Living Ov...
Article
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Cell-based therapies hold promise to substantially curb complications from extreme preterm birth, the main cause of death in children below the age of 5 years. Exciting preclinical studies in experimental neonatal lung injury have provided the impetus for the initiation of early phase clinical trials in extreme preterm infants at risk of developing...
Article
Background: Funded health research is being published in journals that many regard as “predatory”, deceptive, and non-credible. We do not currently know whether funders provide guidance on how to select a journal in which to publish funded health research. Methods: We identified the largest 46 philanthropic, public, development assistance, public-p...
Preprint
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Context : Convergent analyses in different disciplines support the use of the Percentage of Papers by the Most Prolific author (PPMP) as a red flag to identify journals that can be suspected of questionable editorial practices. We examined whether this index, complemented by the Gini index, could be useful for identifying cases of potential editori...
Article
Objectives This study aimed to determine whether there are differences in the language used in grant applications submitted to a Southern Brazil Research Support Foundation (FAPERGS) according to the gender, career stage, and the number of publications of applicants. Study Design and Setting This observational study also evaluated the relationship...
Article
Objectives To describe the processes used to update the PRISMA 2009 statement for reporting systematic reviews, present results of a survey conducted to inform the update, summarise decisions made at the PRISMA update meeting, and describe and justify changes made to the guideline. Methods We reviewed 60 documents with reporting guidance for syste...
Article
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Background Only a small proportion of preclinical research (research performed in animal models prior to clinical trials in humans) translates into clinical benefit in humans. Possible reasons for the lack of translation of the results observed in preclinical research into human clinical benefit include the design, conduct, and reporting of preclin...
Article
Full-text available
Background Literature searches underlie the foundations of systematic reviews and related review types. Yet, the literature searching component of systematic reviews and related review types is often poorly reported. Guidance for literature search reporting has been diverse, and, in many cases, does not offer enough detail to authors who need more...
Preprint
Full-text available
Background: Investigations of transparency, reproducibility and replicability in science have been directed largely at individual studies. It is just as critical to explore these issues in syntheses of studies, such as systematic reviews, given their influence on decision making and future research. We aim to explore various aspects relating to the...
Preprint
Objectives: To measure medical journal Editor-in-Chiefs’ perceptions regarding including patients as (co-)authors on research publications and to measure their views on the application of the ICMJE authorship criteria to patient partners.Design: Cross-sectional survey co-developed with a patient partner Participants: Editor-in-Chiefs of medical jou...
Article
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Background Major depressive disorder is common, debilitating, and affects feelings, thoughts, mood, and behaviors. Childhood and adolescence are critical periods for the development of depression and adolescence is marked by an increased incidence of mental health disorders. This protocol outlines the planned scope and methods for a systematic revi...
Preprint
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Women remain underrepresented in Dentistry in academia, and this gap is widened whenever each career step is progressed. It is of utmost importance to investigate underlying associated factors to predict researchers’ assessment of their gender in Dentistry and the overall STEM (Science, technology, engineering, and mathematics) fields. Thus, we dev...
Article
Background: The objective of this study was to determine the presence of a set of prespecified criteria used to assess scientists for promotion and tenure within faculties of medicine among the U15 Group of Canadian Research Universities. Methods: Each faculty guideline for assessing promotion and tenure was reviewed and the presence of five tradit...
Article
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Background Guidelines recommend that individuals with opioid use disorder (OUD) receive pharmacological and psychosocial interventions; however, the most appropriate psychosocial intervention is not known. In collaboration with people with lived experience, clinicians, and policy makers, we sought to assess the relative benefits of psychosocial int...
Poster
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Case reports are detailed descriptions of a few patients or clinical cases (frequently, one sick person) with an unusual disease or complication, uncommon combinations of diseases, an unusual or misleading semiology, cause or outcome (1). Our primary objective was to assess the completeness of reporting (COR) of case reports published in high impac...
Article
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Introduction: Methodological studies (ie, studies that evaluate the design, conduct, analysis or reporting of other studies in health research) address various facets of health research including, for instance, data collection techniques, differences in approaches to analyses, reporting quality, adherence to guidelines or publication bias. As a res...
Article
Background Even though considered as studies with high methodological power, many RCTs in paediatric dentistry do not have essential quality items in their design, development and report, making results’ reliability questionable, replication challenging to conduct, wasting time, money and efforts, and even exposing the participants to research for...
Article
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Objectives The objective of this review is to identify all preprint platforms with biomedical and medical scope and to compare and contrast the key characteristics and policies of these platforms. Study design and setting Preprint platforms that were launched up to 25 June 2019 and have a biomedical and medical scope according to MEDLINE’s journal...
Article
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Introduction: Two recent high-profile publications (and subsequent retractions) of pharma-coepidemiology studies reporting the effectiveness and risk of hydroxychloroquine in COVID-19 patients received international media attention. Transparent and complete reporting of these studies could have provided peer reviewers and editors with sufficient in...
Article
Objective: The aim of this paper is to review the literature on barriers to conducting replication research and strategies to increase its use and promotion by researchers, editors, and funders. Study Design and Setting: This review was part of a larger meta-narrative review aimed at conducting a concept analysis of replication and developing a rep...
Article
Background: The process of translating preclinical findings into a clinical setting takes decades. Previous studies have suggested that only 5-10% of the most promising preclinical studies are successfully translated into viable clinical applications. The underlying determinants of this low success rate (e.g. poor experimental design, suboptimal an...
Article
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Background : Never before have clinical trials drawn as much public attention as those testing interventions for COVID-19. We aimed to describe the worldwide COVID-19 clinical research response and its evolution over the first 100 days of the pandemic. Methods: Descriptive analysis of planned, ongoing or completed trials by April 9, 2020 testing an...
Article
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The CONSORT 2010 statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency in the evaluation of new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need to undergo rigorous, prospective evaluati...
Article
Full-text available
The CONSORT 2010 statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency in the evaluation of new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need to undergo rigorous, prospective evaluati...
Article
Full-text available
The SPIRIT 2013 (The Standard Protocol Items: Recommendations for Interventional Trials) statement aims to improve the completeness of clinical trial protocol reporting, by providing evidence-based recommendations for the minimum set of items to be addressed. This guidance has been instrumental in promoting transparent evaluation of new interventio...
Article
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Background: Rapid reviews (RRs) are useful products to healthcare policy-makers and other stakeholders, who require timely evidence. Therefore, it is important to assess how well RRs convey useful information in a format that is easy to understand so that decision-makers can make best use of evidence to inform policy and practice. Methods: We as...
Article
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Background: Scopus is a leading bibliometric database. It contains a large part of the articles cited in peer-reviewed publications . The journals included in Scopus are periodically re-evaluated to ensure they meet indexing criteria and some journals might be discontinued for 'publication concerns'. Previously published articles may remain indexed...
Preprint
Background: The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) Statement, published in 2009, was designed to help systematic reviewers transparently report why the review was done, what the authors did and what they found. Over the last decade, there have been many advances in systematic review methodology and terminolo...
Preprint
The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess the trustworthiness and applicability of the review findings. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement was developed to facilitate transparent and complete reporting of systematic reviews an...
Preprint
Objectives: To describe the processes used to update the PRISMA 2009 statement for reporting systematic reviews, present results of a survey conducted to inform the update, summarise decisions made at the PRISMA update meeting, and describe and justify changes made to the guideline.Methods: We reviewed 60 documents with reporting guidance for syste...
Article
Full-text available
The CONSORT 2010 (Consolidated Standards of Reporting Trials) statement provides minimum guidelines for reporting randomised trials. Its widespread use has been instrumental in ensuring transparency when evaluating new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need t...
Article
Full-text available
The CONSORT 2010 statement provides minimum guidelines for reporting randomized trials. Its widespread use has been instrumental in ensuring transparency in the evaluation of new interventions. More recently, there has been a growing recognition that interventions involving artificial intelligence (AI) need to undergo rigorous, prospective evaluati...
Article
Full-text available
Background As production of rapid reviews (RRs) increases in healthcare, knowing how to efficiently convey RR evidence to various end-users is important given they are often intended to directly inform decision-making. Little is known about how often RRs are produced in the published or unpublished domains, and what and how information is structure...
Article
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Background Funders are key players in supporting randomized controlled trial (RCT) data-sharing. This research aimed to describe commercial and non-commercial funders' data-sharing policies and to assess the compliance of funded RCTs with the existing data-sharing policies. Methods and findings Funders of clinical research having funded at least o...
Article
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Objective To generate an understanding of the communication practices that might influence the peer-review process in biomedical journals. Method Recruitment was based on purposive maximum variation sampling. We conducted semistructured interviews. Data were analysed using thematic analysis method. Participants 56 journal editors from general med...
Article
Systematic reviews of diagnostic test accuracy (DTA) studies are fundamental to the decision making process in evidence based medicine. Although such studies are regarded as high level evidence, these reviews are not always reported completely and transparently. Suboptimal reporting of DTA systematic reviews compromises their validity and generalis...
Article
Objective Over 400 reporting guidelines are currently published, but the frequency of their use by authors to accurately and transparently report research remains unclear. This study examined citation counts of reporting guidelines and characteristics contributing to their citation impact. Study Design and Setting Web of Science database was searc...
Article
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For knowledge to benefit research and society, it must be trustworthy. Trustworthy research is robust, rigorous, and transparent at all stages of design, execution, and reporting. Assessment of researchers still rarely includes considerations related to trustworthiness, rigor, and transparency. We have developed the Hong Kong Principles (HKPs) as p...
Preprint
During the COVID-19 pandemic, the rush to scientific and political judgments on the merits of hydroxychloroquine was fuelled by dubious papers which may have been published because the authors were not independent from the practices of the journals in which they appeared. This example leads us to consider a new type of illegitimate publishing entit...
Article
Full-text available
Background: Clinicians, patients, and policy-makers rely on published evidence from clinical trials to help inform decision-making. A lack of complete and transparent reporting of the investigated trial outcomes limits reproducibility of results and knowledge synthesis efforts, and contributes to outcome switching and other reporting biases. Outco...
Article
Objective The aim of this paper is to clarify the concept of replication research in order to improve its appropriate use by researchers, editors, research funders and decision makers. Study Design We combined concept analysis and meta-narrative review methods to synthetize knowledge on replication research from various scientific fields. We used...
Article
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Objective To determine the presence of a set of pre-specified traditional and non-traditional criteria used to assess scientists for promotion and tenure in faculties of biomedical sciences among universities worldwide. Design Cross sectional study. Setting International sample of universities. Participants 170 randomly selected universities fro...
Preprint
Full-text available
Background: The Annals of Internal Medicine (AIM) has adopted a policy encouraging data-sharing since 2007. Objective: To explore the impact of the AIM data-sharing policy for randomized controlled trials (RCTs) in terms of output from data-sharing (i.e. publications re-using the data). Design: Retrospective study. Setting: AIM. Participants: RCTs...
Article
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This is a protocol for a co‐registered Cochrane and Campbell Review (Methodology). The objectives are as follows: To identify, describe and assess methods for: when to replicate a systematic review; how to replicate a systematic review.
Article
Background: The process of translating preclinical findings into a clinical setting takes decades. Previous studies have suggested that only 5-10% of the most promising preclinical studies are successfully translated into viable clinical applications. The underlying determinants of this low success rate (e.g. poor experimental design, suboptimal an...
Article
Full-text available
Background: Scopus is a leading bibliometric database. It contains the largest number of articles cited in peer-reviewed publications . The journals included in Scopus are periodically re-evaluated to ensure they meet indexing criteria and some journals might be discontinued for publication concerns. These journals remain indexed and can be cited....
Article
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Background: The increase in the number of predatory journals puts scholarly communication at risk. In order to guard against publication in predatory journals, authors may use checklists to help detect predatory journals. We believe there are a large number of such checklists yet it is uncertain whether these checklists contain similar content. We...
Article
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Objective To evaluate the impact of an editorial intervention to improve completeness of reporting of reports of randomised trials. Design Randomised controlled trial (RCT). Setting BMJ Open ’s quality improvement programme. Participants 24 manuscripts describing RCTs. Interventions We used an R Shiny application to randomise manuscripts (1:1 a...
Preprint
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Objectives: The objective of this review is to identify all preprint platforms with biomedical and medical scope and to compare and contrast the key characteristics and policies of these platforms. We also aim to provide a searchable database to enable relevant stakeholders to compare between platforms. Study Design and Setting: Preprint platforms...
Preprint
Full-text available
Background: Many randomized controlled trials (RCTs) are biased and difficult to reproduce due to methodological flaws and poor reporting. There is increasing attention for responsible research practices including reporting guidelines, but it is unknown whether these efforts have improved RCT quality (i.e. reduced risk of bias). We therefore mapped...
Article
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Background: When a journal receives a duplicate publication, the ability to identify the submitted work as previously published, and reject it, is an assay to publication ethics best practices. The aim of this study was to evaluate how three different types of journals, namely open access (OA) journals, subscription-based journals, and presumed pr...
Article
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Objective A current assessment of case reports of possible drug-induced pancreatitis is needed. We systematically reviewed the case report literature to identify drugs with potential associations with acute pancreatitis and the burden of evidence supporting these associations. Methods A protocol was developed a priori (PROSPERO CRD42017060473). We...
Article
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Background: The randomized controlled trial (RCT) is considered the gold standard study design to inform decisions about the effectiveness of interventions. However, a common limitation is inadequate reporting of the applicability of the intervention and trial results for people who are "socially disadvantaged" and this can affect policy-makers' d...
Preprint
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Background Scopus is a leading bibliometric database. It contains the largest number of articles cited in peer-reviewed publications. The journals included in Scopus are periodically re-evaluated to ensure they meet indexing criteria and some journals might be discontinued for publication concerns. These journals remain indexed and can be cited. Th...
Article
Objectives Appropriate use of reporting guidelines of health research ensures that articles present readers with a consistent representation of study relevance, methodology and results. This study evaluated the use of major reporting guidelines. Study Design and Setting A cross-sectional analysis of health research articles citing four major repor...
Article
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Introduction Transparent and accurate reporting is essential for readers to adequately interpret the results of a study. Journals can play a vital role in improving the reporting of published randomised controlled trials (RCTs). We describe an RCT to evaluate our hypothesis that asking peer reviewers to check whether the most important and poorly r...
Article
Full-text available
Background Compression ultrasonography (CUS) is the first-line imaging test in the diagnostic management of suspected deep vein thrombosis (DVT) of the lower extremity. Three CUS strategies are used in clinical practice. However, their relative diagnostic accuracy is uncertain. Objectives This systematic review and meta-analysis aimed to summarize...
Article
Full-text available
Introduction With its legalisation and regulation in Canada in 2018, the proportion of Canadians reporting cannabis use in 2019 increased substantially over the previous year, with half of new users being aged 45+ years. While use in older adults has been low historically, as those born in the 1950s and 1960s continue to age, this demographic will...
Article
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Introduction: There has been a growing awareness of the need for rigorously and transparent reported health research, to ensure the reproducibility of studies by future researchers. Health economic evaluations, the comparative analysis of alternative interventions in terms of their costs and consequences, have been promoted as an important tool to...

Citations

... With the production of systematic reviews and meta-analyses increasing exponentially [39,67] and expanding into many other areas of science [68,69], investment in strategies to improve their conduct and reporting could benefit the many different stakeholders who rely on synthesised evidence for decision-making. We anticipate that results of the REPRISE project will also draw attention to the potential value of replicating systematic reviews, which to date has been underrecognised by researchers, funders, journals and other stakeholders, and inform updates to guidance on when and how to replicate systematic reviews [18,70]. ...
... Le premier article que nous citons en est une illustration. Il est d'ailleurs cité dans un manuscrit mis en ligne sur MetaArXiv traitant de la problématique des revues dites d'autopromotion (self-promotion journals), c'est-àdire publiant une forte proportion d'articles rédigés par un même groupe de chercheurs, notamment des chercheurs ayant des liens privilégiés avec les membres du comité de rédaction de la revue, et alors même que ces articles présentent les résultats de travaux de recherche de faible qualité [45]. ...
... As mandates for OA, such as the NIH Public Access Policy and Plan S (developed by cOAlition S), gain popular support, the nuances of OA publishing will increasingly dictate researchers' publication practices [9]. At the same time, there is no universal standard for obtaining funds to cover these charges, let alone regulation of the charges themselves [16]. ...
... To address this, the SPIRIT-AI and CONSORT-AI Steering Group announced in October 2019 an initiative to develop evidencebased extensions for clinical trial protocols and reports involving AI interventions [19]. The SPIRIT-AI [20][21][22] and CONSORT-AI [23][24][25] guidelines have since been developed in accordance with the EQUATOR (Enhancing the Quality and Transparency of Health Research) Network recommendations. The guidelines were developed using a Delphi methodology with an international multidisciplinary consortium. ...
... Since then, extensions of other reporting guidelines specifically focusing on the reporting of abstracts have been developed. Currently reporting guidelines for abstracts are available for at least five types of study designs: clinical trials, observational studies, systematic reviews, test accuracy studies, overviews of systematic reviews, and multivariable prediction models [15,16]. More are likely to follow. ...
... It has been more than a decade since the original publication of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement [1], and it has become one of the most cited reporting guidelines in biomedical literature [2,3]. Since its publication, multiple extensions of the PRISMA Statement have been published concomitant with the advancement of knowledge synthesis methods [4][5][6][7]. ...
... Our results are consistent with others (Fang et al., 2020;Bero et al.,1998) which appears a need to use specific strategies to implement research-based recommendations to ensure a change in approach. Study concluded that journals' active implementation of the CONSORT -A guidelines is associated with improved completeness of reporting of RCTs (Speich et al., 2020). Currently, of the ten nursing journals, six (EJCN, NET, WB, NO, EJCC, JFN) endorsed CONSORT guidelines for full text reporting, none of them endorse the CONSORT-A. ...
... We have adopted an extension to the PRISMA statement for Reporting Literature Searches in Systematic Reviews (PRISMA-S) (17). A comprehensive search of general electronic databases and a manual search will be done to identify relevant studies (from inception up to 16 June 2021). ...
... However, when the D-dimer is greater than the threshold value [70], and when the calculated probability/risk is moderate to high, the recommended initial diagnostic method is a Doppler ultrasound [68,71]. Moreover, compression ultrasonography (CUS) is the first-line imaging test in the diagnostic management of suspected deep vein thrombosis (DVT) of the lower extremity [14]. Although Venography [66,67] is considered the gold standard for the diagnosis of DVT [14], its use in clinical applications is limited, mainly because it is an invasive method that requires an injection with contrast (biomaterial) to observe the displacement of blood flow in the circulatory system, which, in addition to being expensive, is risky for the patient's health, so its use in clinical applications is limited. ...
... Second, SPIRIT-AI [20][21][22] and CONSORT-AI [23][24][25] are specific to clinical trials, whereas it should be recognised that most current evaluations of AI systems are some form of diagnostic accuracy or prognostic model study. AI-specific guidelines that will address such studies, STARD-AI [28] (Standards for Reporting Diagnostic Accuracy Studies -Artificial Intelligence) and TRIPOD-AI [29] (Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis -Artificial Intelligence), are currently under development. Whilst there are likely to be common elements between these AI extensions, investigators reporting should use, and reviewers appraising should receive, the most suitable guideline available which considers both the study design and the type of intervention. ...