Dania Omer's research while affiliated with Al-Nahrain University and other places

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Publications (2)

Research methodology employed to develop a subunit MEV vaccine against Hi
SOPMA secondary structure prediction of FtsN protein. Yellow color bars...
Prediction of FtsN 3D structure and its evaluation: AFtsN refined 3D...
HLA alleles population coverage analysis of FtsN epitopes according to...
+9 Sequence overview of the MEV construction. It has 149 amino acids,...
Immunoinformatics design of multi-epitope peptide-based vaccine against Haemophilus influenzae strain using cell division protein
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  • Nov 2022
Haemophilus influenzae is a pathogen that causes invasive bacterial infections in humans. The highest prevalence lies in both young children and adults. Generally, there are no vaccines available that target all the strains of Haemophilus influenzae. Hence, the purpose of this research is to employ bioinformatics and immunoinformatics approaches to...
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In vitro evaluation of antioxidant and cytotoxic activity of folate-methotrexate conjugated to bovine serum albumin nanoparticles against MCF-7, HepG2, and PC3 cell lines
Article
  • Aug 2022
This study assesses the antioxidant characteristics of folate-methotrexate that has been conjugated to bovine serum albumin nanoparticles (FO-MTX-BSA-NPs) as well as its cytotoxic impacts on MCF-7 (human breast adenocarcinoma), HepG2 (human liver cancer) and PC3 (human prostate cancer) cell lines in vitro. A 2,2-diphenyl-1-picrylhydrazyl (DPPH) ass...
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Citations

... At present, the accumulation of a large amount of genetic and structural information about pathogens in specialized databases makes it possible to use the crystal structures of viral proteins to identify potential immunogenic epitopes and predict subunit vaccines based on them using immunoinformatics approaches [44][45][46][47][48]. In addition, the development of bioinformatic tools for predicting the host's immune response allows in silico evaluation of the effectiveness of these vaccines. ...
Reference: An Algorithm for the Development of a Recombinant Antiherpetic Subunit Vaccine Combining the Crystal Structure Analysis, AlphaFold2-Based Modeling, and Immunoinformatics
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... The cytotoxicity of these substrates was evaluated by the 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) assay [31,32]. MCF-7 cells were seeded in 96-well plates at 5000 cells per well using Dulbecco's Modified Eagle's Medium (DMEM) supplemented with 1% penicillin/streptomycin and 10% fetal bovine serum. ...
Reference: Mg-Doped ZnO Nanoparticles with Tunable Band Gaps for Surface-Enhanced Raman Scattering (SERS)-Based Sensing
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