Cynthia Goh's research while affiliated with Duke-NUS Medical School and other places

Publications (28)

Article
Full-text available
This is a case description and personal account shared by a palliative care physician whose team provided specialist palliative care support to a patient who attempted immolation. This case depicts a family at risk of complicated grief due to the violent nature of self-inflicted burns and the lingering social stigmatization of suicide. Here, we exp...
Article
Facing the possibility of a surge of COVID-19-infected patients requiring ventilatory support in Intensive Care Units (ICU), the Singapore Hospice Council and the Chapter of Palliative Medicine Physicians forward its position on the guiding principles that ought to drive the allocation of ICU beds and its role in care of these patients and their fa...
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Purpose: To evaluate the linguistic and psychometric properties of the Functional Living Index-Cancer (FLIC) in assessing the quality of life of Chinese cancer patients. Methods: The English FLIC was translated into Traditional Chinese by the standard forward-backward procedure. After cognitive debriefing, a Traditional Chinese FLIC was administ...
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Introduction: More than half of all deaths in Singapore occur in hospitals. Little is known about the quality of care received by dying patients in hospitals. The Liverpool Care Pathway (LCP) provides a framework of providing good end-of-life care for dying patients and has been used with success in the United Kingdom (UK). In this study, we inves...
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Purpose: To compare the measurement precision and related properties between the 5-level EuroQoL Group's 5-dimension (EQ-5D-5L) questionnaire and the Functional Assessment of Cancer Therapy-Breast (FACT-B) questionnaire in assessing breast cancer patients. Methods: An observational study of 269 Singaporean breast cancer patients. To compare disc...
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Context: The Functional Assessment of Cancer Therapy--Breast Symptom Index (FBSI) is an eight-item instrument extracted from the Functional Assessment of Cancer Therapy--Breast (FACT-B). There has been no formal assessment of this eight-item version. Objectives: This study aimed to examine the measurement properties of and comparability between...
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Background: The traditional relationship between patient and physician in East Asian society has often been described as "paternalistic." However, in an increasingly Westernized world, our knowledge of how patients perceive the role of the physician in their decision making regarding treatment is lacking. Objective: This article is part of a lar...
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Objective: To examine the measurement properties of and comparability between the English and Chinese versions of the five-level EuroQoL Group's five-dimension questionnaire (EQ-5D) in breast cancer patients in Singapore. Methods: This is an observational study of 269 patients. Known-group validity and responsiveness of the EQ-5D utility index a...
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This study aimed to describe the patterns of sedative use among terminally ill cancer patients who were referred to a hospital-based specialist palliative care service for symptom management. It also aimed to examine whether sedative use among terminally ill cancer patients during the last two days of life had any impact on their survival. A retros...
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To describe the place of death for patients with cancer in Singapore from 2000 to 2009, and determinants of death at home and in in-patient hospice compared to death in hospital. Cross-sectional analysis of all patients registered with the Singapore Cancer Registry who had died in the study period (N=52120). Places of death were grouped as homes, i...
Article
The objective of the study was to examine the measurement properties of and comparability between the English and Chinese versions of the Functional Assessment of Cancer Therapy-Breast (FACT-B) in breast cancer patients in Singapore. This is an observational study of 271 Singaporean breast cancer patients. The known-group validity of FACT-B total s...
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Previous studies have focused either on advance medical directives rather than advance care planning (ACP), or on patient's perspectives on ACP rather than those of the health-care providers. This study aimed to explore the knowledge, attitudes and experience of renal health-care professionals in Singapore on ACP for patients with end-stage renal f...
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Concerns about the life shortening effect of opioids is a well known fact in the medical world when considering administration of these drugs for symptom alleviation at end of life. This study described the patterns of opioid use among cancer patients referred to a hospital-based specialist palliative care service for symptom management. This study...
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A Royal Statistical Society Working Party recently recommended that "Greater use should be made of numerical, as opposed to verbal, descriptions of risk" in first-in-man clinical trials. This echoed the view of many clinicians and psychologists about risk communication. As the clinical trial industry expands rapidly across the globe, it is importan...
Data
Appendix 1. Example of Card 1 using frequency format in the least to most severe sequence and the complementing Card 2 that uses all three formats in the same sequence.
Article
The objective of this study has been to examine the frequency of use of artificial hydration in terminally ill cancer patients during the last 48 h of life and the occurrence of symptoms specific to hydration status. Other objectives were to find out if artificial hydration has any impact on survival or had any influence on the patterns of use of o...
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Opioid drug response and pain perception differs greatly amongst different individuals. The micro-opioid receptor (MOR) is the main receptor target for important opioid analgesics. As SNPs may contribute to interindividual differences in drug response, in silico signatures of recent positive selection (RPS) were utilized to seek out potentially fun...
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Full-text available
Health-related quality of life is an important aspect of health outcome. The assessment of it must be done by validated instruments. There is no published data on the validity, reliability and sensitiveness to change of the official Chinese translation of the Functional Assessment of Cancer Therapy-General (version 4; FACT-G). A Chinese questionnai...
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This study aims to develop a function for mapping the English and Chinese versions of the Functional Assessment of Cancer Therapy-General (FACT-G) scores to the EuroQoL Group's EQ-5D utility index and to test whether a single function is sufficient for the two language versions. A baseline survey of 558 cancer patients in Singapore using the FACT-G...
Article
To assess measurement equivalence of the Singaporean English and Chinese versions of the EuroQol Group's 5-domain questionnaire (EQ-5D) in cancer patients. Seven hundred and seventy-one ethnic Chinese patients in Singapore were recruited, and they answered either an English or a Chinese version of the EQ-5D. Seven days later, a similar questionnair...
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To assess whether scores on the three major quality-of-life questionnaires in oncology (FACT-G, FLIC, and EORTC QLQ-C30) are associated with modes of administration in a realistic clinical research setting. A heterogeneous sample of 1,265 cancer patients was recruited in Singapore. About one-fourth of the patients chose to have the interview admini...
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To compare the variability and sample size requirements of the global quality-of-life (QOL) scores of the following three major QOL instruments: the Functional Assessment of Cancer Therapy-General (FACT-G), Functional Living Index-Cancer (FLIC), and European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire C30 (E...
Article
Full-text available
In methodological studies and outcomes research, questionnaires often comprise several health-related quality of life (HRQoL) measures. Previous psychological studies have suggested that changing the sequential order of measurement scales within a questionnaire could alter the pattern of responses. Yet, information on the presence or absence of ord...
Article
English and Chinese are two of the most widely used primary languages in the world. Patients in many cancer centers have a variety of ethnic backgrounds and primary languages. The comparability of version 4 of the English and Chinese versions of the Functional Assessment of Cancer Therapy-General (FACT-G) and version 3 of the European Organization...
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Methodological studies and outcome research often include several health-related quality of life (HRQoL) measurement scales in one questionnaire. Psychological studies have previously demonstrated that changing the sequential order of measurement scales within a questionnaire can alter the pattern of responses. Little is known, however, about wheth...

Citations

... The authors suggest that the physician's belief system informs and is informed by their self-concepts of identity which are in turn rooted in their self-concepts of personhood -how they conceive what makes them who they are [11]. This posit not only ties reflective practice to the shaping of the physician's moral and ethical compass but also offers evidence of it's role in their professional identity formation (PIF) [8,[12][13][14][15][16][17][18][19][20][21][22][23]. With PIF [8,24] occupying a central role in medical education, these ties underscore the critical importance placed on integrating reflective practice in medical training. ...
... These findings provide novel insight into a structured framework that may help guide the experiences, training, assessment, and oversight of peer-mentors beyond the auspices of our local program. These general observations will equip host organizations with the direction they need to take in designing and executing peer-mentoring training and assessment Introduction A shortage of experienced clinical mentors [1], changing mentoring and clinical practice, and shifting expectations upon mentees, mentors and mentoring relationships particularly during the COVID-19 pandemic [2][3][4][5] has seen mentoring programs struggle [6]. Traditional concepts of dyadic relationships between an experienced and trained physician and a medical student or junior doctor have come under scrutiny over their ability to contend with raising concerns over gaps in structure [7,8], assessment and oversight [9] of mentoring relationships and the mentoring environment [10,11]. ...
... One publication presented data regarding the appropriateness of an ePRO application [29]. Two articles compared the properties of the FACT-B (disease-specific measure) with that of a general HRQoL measure, the EQ-5D [25,28]. ...
... (2) Measured by the validated Chinese version of the brief pain inventory (BPI-C) (Wang et al. 1996), which is the most commonly used assessment scale in measuring the severity of pain symptoms in cancer patients. (3) Healthrelated quality of life was calculated using the validated Chinese version of the quality of life measurement scale for breast cancer patients (FACT-B) (Wan et al. 2007;Ng et al. 2012), which reaches a composite index score reflecting the disease-specific health-related quality of life scores in the physical, social/family, emotional, functional, and additional concerns dimensions. ...
... The ic-mt and gc-mt groups received eight 40-minute sessions of cmt over 2 weeks in addition to oncotherapy and usual care; the ctrl group received only oncotherapy and usual care. Patients were assessed at baseline and 2 weeks later using the Cancer Coping Modes Questionnaire (ccmq) 30 , the Psychological Adjustment Scale for Cancer Patients (pascp) 31 , and the Functional Living Index-Cancer (flic) [32][33][34] . At 12 and 24 months after the intervention, individual telephone interviews were conducted to investigate the global psychological and somatic status and length of life of patients in the study groups. ...
... To circumvent the shortage of SPC presence on many wards, the small teams established symptom control guidelines, provided telephone advice and made palliative care resources available online. 5 Secondly, in pre-empting the overwhelming of the healthcare system, focus was placed on discharge and advanced care planning conversations whenever possible. Although symptom management was not at risk, manpower limitations raised concerns over the compromise of holistic support provided to sickly patients and families that were physically separated from one another. ...
... The Chinese translation of the FBSI has demonstrated adequate test-retest reliability as well as known-group validity and convergent and divergent validity [32]. Garcia et al. [33] sought to develop a new version of the FBSI in accordance with US Food and Drug Administration guidance for PRO measures that provides assessment on a symptom level and improves upon the original FBSI by emphasizing input from patients. ...
... This may lead to the unintended exclusion of articles from other settings. As concepts of MD and personhood are sociocultural constructs, the omission of non-English articles may have significant ramifications on the applicability of these findings in Confucian-inspired societies [31,[116][117][118][119]. [31] Here relational autonomy, filial piety and family-centric associations play a critical role in self-concepts of identity and personhood and thus suggest that concepts of MD [120][121][122][123][124][125] in these settings may be different and not fully reflected by our findings. ...
... The EQ VAS score is related to the EQ-5D-5L and used to rate the overall health on a scale from 0 (worst imaginable health state) to 100 (best imaginable health state) [26]. The EQ-5D-5L is widely recognized as a HRQoL measurement tool for cancer patients and has been validated in breast cancer patients [31,32]. ...