Cícero Lourenço da Silva’s scientific contributions

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Publications (2)


Figure 1. Flowchart based on the PRISMA model with parameters used in the search and selection of publications.
Figure 2. General aspects of C. leprosum. A. Habit. B. Stem. C. General appearance of the sheet. D. Fruits.
Biological and pharmacological activity of C. leprosum.
Combretum leprosum Mart.: Botany, Ethnomedicinal Uses, Biological Activities, Phytochemistry and Conservation Needs
  • Article
  • Full-text available

August 2022

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152 Reads

Research Society and Development

Bruno Melo de Alcântara

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Ariston Oliveira Magalhães Filho

Combretum leprosum is a plant species with wide distribution in Brazil known as "mofumbo", standing out in studies associated with its pharmacological and ethnobotanical activity. The medicinal applications of the species are widely reported in the literature, using the bark, leaves and flowers as healing agents. Given the economic, pharmacological and ecological importance, this work aimed to present a systematic review of production, conservation status and knowledge about the species in different fields of knowledge. The literature review was based on seven categories, 2 application is focused on antitumor action, treatment against Chagas disease, antinociceptive behavior, antibacterial, antioxidant, anti-inflammatory and antiproliferative action. Among the compounds isolated from C. leprosum with different applications, 3β-6β-16β-trihydroxylup-20(29)-ene stands out, a lupane triterpene isolated from different parts of the plant, associated with different medicinal and therapeutic applications. The species was highlighted in works associated with environmental regeneration, being resistant to different phytophysiognomies and showing tolerance to environments contaminated by heavy metals, being able to represent an important species in reforestation programs and recovery of degraded environments. However, even with the growing number of studies associated with C. leprosum in recent years, the species does not have an assessment regarding its degree of threat, demonstrating the need for research associated with the species and the possible impacts that its representatives may suffer, helping in sustainable development and conservation programs.

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Indication of herbal medicines and medicinal plants by the doctors of Basic Health Units

June 2022

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50 Reads

Research Society and Development

In Brazil, the use of medicinal plants in the treatment of illnesses is influenced by indigenous, African and European cultures. Approximately 80% of the world population uses plants or their preparations in health care, making it a complementary therapy. Thus, the objective was to identify the indication made by doctors working in the Family Health Strategy for medicinal plants and/or herbal medicines. Thirty-one doctors from the Basic Health Units located in Juazeiro do Norte-CE were interviewed, using semi-structured forms. For data analysis, the Microsoft Excel 2010 program was used. 23 plant species indicated for medicinal purposes and 19 phytotherapeutic purposes were identified, and Cymbopogon citratus (DC.) Stapf, Matricaria chamomilla L., Aloe vera L. Burm.f. and Peumus boldus Molina were more representative among plants, and Valeriane® (Valeriana officinalis L.); Calman® (Passiflora incarnata L., Crataegus oxyacantha L. and Salix alba L.); Ginkgo biloba® Extract (Ginkgo biloba L.); Sintocalmy® (Passiflora incarnata L.) and Liberaflux® (Hedera helix L.) were the most representative among herbal medicines. It was found that doctors recommend plants and/or herbal medicines in the treatment of certain diseases, however further study is needed regarding their use and dosage.