Chul-Ho Park's research while affiliated with Chonnam National University and other places
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Publications (34)
Porcine rotaviruses cause severe economic losses in the Korean swine industry due to G- and P-genotype mismatches between the predominant field and vaccine strains. Here, we developed a live attenuated trivalent porcine group A rotavirus vaccine using 80 cell culture passages of the representative Korean predominant strains G8P[7] 174-1, G9P[23] PR...
This report describes a case of newly recognized congenital Müllerian duct anomaly in a bitch. A fourteenyear-old, mixed breed bitch was presented with mild hematuria and mammary gland tumor. Complementary examinations were performed and abdominal ultrasonography revealed distended uterine horns and uterine tumor-like mass around the right ovarian...
Sapoviruses (SaVs) cause severe acute gastroenteritis in humans and animals. Although they replicate in intestinal epithelial cells, which are tightly sealed by apical-junctional complexes, such as tight junctions (TJs), the mechanisms by which SaVs hijack TJs and their proteins for successful entry and infection remain largely unknown. Here, we de...
The current study describes a case of endometrial polyps accompanied by an open-cervix pyometra in a 15-year-old female Chinchilla Persian cat. The cat was presented with a history of a large mass in the endometrium and purulent discharge from the vulva. Ovariohysterectomy was performed and pedunculated polypoid mass on the endometrium was seen pro...
Sapoviruses cause acute gastroenteritis in both humans and animals. However, the host signaling pathway(s) that facilitates host cell entry by sapoviruses remains largely unknown. Here we demonstrate that porcine sapovirus (PSaV) activates both PI3K/Akt and MEK/ERK cascades at an early stage of infection. Removal of cell surface receptors decreased...
Cell-free fetal RNA is useful to determine fetal sex and detect other inherent genetic disorders. However, non-invasive fetal sex determination methods using fetal RNA from maternal plasma is not yet well established in studies pertaining to bovine animals. Thus, the aim of this study was to systematically evaluate the presence of the male-specific...
The objective of this study was to evaluate the initial detection time and development of the fetal genital structures using ultrasound in twelve pregnant small bitches. The initial detection time of the fetal genital structures was as follows: genital tubercle at days 32.6; os penis at days 45.2; labia at days 45.7; scrotum at days 47.5. Ultrasono...
A 10-year-old spayed female Yorkshire Terrier visited for a physical checkup. The bitch had a history of ovariohysterectomy for treatment of pyometra a year ago. On physical examination, the dog was bright and alert. Complete blood counts, serum biochemistry and blood gas analysis results did not show any deviations within normal ranges. Radiograph...
This study was performed to establish a new parameter for estimating gestational age and predicting parturition day by ultrasonographic measurement of deep portion of telencephalic vesicle (DPTV) diameter in small dogs. Fetal head diameter (HD) and DPTV diameter were measured in 15 pregnant Pekingese bitches, from Day 15 to the parturition day, and...
Cell-free fetal RNA has been highlighted as useful tools for the fetal sex determination or other genetic inherentdisorder. However, there is no knowledge about the sex determination using cell free fetal RNA in bovine field. Thus,the present study aimed to evaluate the presence of transcripts of DDX3Y, USP9Y and ZRSR2Y genes in maternalplasma of p...
The aim of this study was to estimate of ovulation time and parturition day at the same time as breeding in smalldog by vaginal cytology and to confirm the accuracy by comparing the expected parturition day and the real one.
Characteristic features of vaginal cytology during the estrous cycle were the high proportion of large intermediatecell, supe...
Citations
... Vaginal cytology is proposed as a fast, affordable, and cheap method of determining the stage of the estrous cycle of dogs, and also allows to neglect the determination of hormone concentrations, help determine the time of artificial or natural insemination, and determine the effect of estrogen on the reproductive organs of a dog (Sharma & Sharma, 2016;England, 2016;Rosnina et al., 2017;Antonov, 2017;Meliou, 2018;Park et al., 2019). ...
... The two outer capsid proteins VP7 and VP4 are commonly used for further classification of strains, defining the G and P genotypes, respectively (Matthijnssens et al., 2011). Currently, 42 G and 58 P genotypes have been identified in human and animals, among which six G genotypes (G1, G2, G3, G4, G9, and G12) and 3 P genotypes (P [4], P [6], P [8]) are globally prevalent (Desselberger, 2014;Crawford et al., 2017;Park et al., 2019). Among the P genotypes, P [8] is the most prevalent. ...
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... The virus was then concentrated by ultracentrifugation. The viral titer was determined by median tissue culture infective dose (TCID 50 ) assay as described previously [44] and calculated by the method of Reed and Muench [45]. ...
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... Recent research shows that miR-21, via PTEN/PI3K/AKT signal pathways, influences the biological behaviors of malignant cells, especially cell proliferation [41][42][43][44]. The PI3K/AKT and MAPK pathways have been well documented to be major intracellular signaling pathways stimulated by BAs [45,46]. In CRC cells, PI3K/AKT signaling is activated by conjugated BA and deoxycholyltaurine and then stimulated in CRC cell survival and proliferation. ...
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... Data were analyzed using a program included in the Applied Biosystems StepOne software v2.1 package, using the ΔΔCT method. Each experiment was repeated three times [16,17]. ...
