Christopher Hinds's research while affiliated with University of Oxford and other places

... However, because people's real-time demand for face recognition is not very high, the MTCNN algorithm with a slow running speed but higher accuracy is selected to provide face recognition at the edge [15]. e MTCNN mode mainly uses three cascaded network systems, such as Proposal Network (P-Net), Refine Network (R-Net), and Output Network (O-Net) to achieve faster and more effective face data monitoring [16]. is mode also uses key techniques such as image pyramid, border recycling, and off-peak control [17]. ...

... 200,201 The effect of the rs1006737 genotype and its interaction with LTCC antagonism could be clarified by the Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS), an exploratory experimental medicine study of the LTCC antagonist nicardipine given to participants with high mood instability. 202 To date, observational studies have reported contradictory associations between CCBs intake and mood disorders (see Supplementary material online, Table S1). In a longitudinal study based on a large hospital database of patients hospitalized for mood disorders, the use of CCBs and β blockers was associated with an increased risk of admission for mood disorders. ...

... Currently, there is robust evidence regarding the correlation between endoscopic disease activity and FC values in UC. Walsh et al. evaluated the association between FC and endoscopic disease activity assessed by the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) score [23]. A strong correlation was identified (r = 0.741, 95% CI 0.289-0.922, ...

... This protein has become a focus of intense clinical as well as research interest. Recent data demonstrate that faecal calprotectin (FC) correlates with endoscopic activity in ulcerative colitis, and may predict histological healing [31]. In 109 patients with UC who presented for colonoscopy, FC correlated more closely than CRP or clinical activity index with endoscopic disease activity (Spearman's rank correlation coefficient r =0.834) [32]. ...

... Integration with existing structures of any e-health system is vital. It means that the data input from patients will be available to clinicians in real time, as in some proven applications (whch were also in the IDB context) (Calvert et al, 2013;Naghibi et al, 2014;Squires et al, 2016;Squires et al, 2017;Walsh et al, 2018). ...

... In terms of intervention, the present study provided compelling evidence on sleep disturbance as a transdiagnostic mediator and the corresponding moderate to large effect sizes underscore the importance of treating sleep disturbance to improve psychopathology in children/adolescents exposed to ACEs. Recent clinical trials have shown that cognitive behavioral therapy (CBT) for sleep disturbance is efficacious for adults suffering from depression (Cunningham & Shapiro, 2018), PTSD (Ho et al., 2016), and psychosis (Freeman et al., 2017). There is also growing evidence on the efficacy of thirdwave CBT for sleep disturbance (Rash et al., 2019). ...

... In the context of the BD, most of the studies assessing the possible effect of the FA administration focus on the depressive aspect of the disorder (e.g. Bedson et al. 2014;Rakofsky and Dunlop 2014;Geddes et al. 2016;Nierenberg et al. 2017;Sarris 2017;Tunbridge et al. 2017;Simon et al. 2018), all them indicating weak evidence to support the use of the drug in patients at this phase. In addition, at present, no paper was designed assessing the effect of FA, alone or combined with a mood stabilizer, in an animal model exclusively mimicking the BD manic phase. ...

... Such approaches fall into the category of ambulatory assessment 24 . Other researchers have developed smartphone apps for patient daily self-reports 25,26 , while still others have explored real-time self-report assessment repeatedly throughout the day using techniques known as ecological momentary assessment (EMA) 6 . In short, there are a plethora of different approaches being explored. ...

... 6 As a sequel to BALANCE, the combination therapy study CEQUEL published in The Lancet Psychiatry does not disappoint. 7 But to facilitate success, John Geddes and colleagues have drawn on many of the original "cast" and produced the study against a backdrop of real-world practice. Here, quetiapine is often given short-term to ameliorate acute symptoms, especially those associated with anxiety, and this allows other coprescribed drugs to gain traction. ...

... However, one risk factor that has not been identified in qualitative work but reported in the current study is 'recency of violence post-sentence'. Some of these clinical factors are contained in other risk assessment tools, such as FoxWeb [26] which is based around 10 modifiable factors, and has been recently validated [27]. As with FoVOx, FoxWeb is quick to complete, includes predictors that are reliably coded, and requires little training. ...