Christine L. Emsley's research while affiliated with Indiana University-Purdue University Indianapolis and other places

Publications (15)

Article
Full-text available
To test the effects of a computer-based nursing intervention designed to provide patients and family caregivers with concrete, objective information on symptom management; provide education about disease and treatment; coordinate medical resources; and provide emotional support and counseling. Two-site, randomized clinical trial. A large, urban, mi...
Article
The epidemiology and natural history of cognitive impairment that is not dementia is important to the understanding of normal aging and dementia. To determine the prevalence and outcome of cognitive impairment that is not dementia in an elderly African American population. A two-phase, longitudinal study of aging and dementia. A total of 2212 commu...
Article
Objective: To study the clinical effectiveness of Swedish massage in fibromyalgia syndrome [FMS]. Methods: Swedish massage [SM] was compared with standard physician care [SC] without or with interim follow-up telephone calls [SCPC] in 37 subjects. Results: Baseline Arthritis Impact Measurement Scales [AIMS] of physical activity, depression, anxiety...
Article
Findings on the risk of bone fractures associated with long-term fluoride exposure from drinking water have been contradictory. The purpose of this study was to determine the prevalence of bone fracture, including hip fracture, in six Chinese populations with water fluoride concentrations ranging from 0.25 to 7.97 parts per million (ppm). A total o...
Article
To determine the association between medications that ameliorate vascular risk factors and the prevalence of cognitive impairment and dementia in an older African-American population. A community-based survey to identify subjects with and without evidence of cognitive impairment and subsequent diagnostic evaluation of a stratified sample of these s...
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The Community Screening Interview for Dementia (CSI 'D') was developed as a screening instrument for dementia for use in cross-cultural studies. It consists of two components, a cognitive test for non-literate and literate populations and an informant interview regarding performance in everyday living. The development of the CSI 'D', involving harm...
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A prospective study to investigate health-related quality of life (HRQOL) outcome in patients with temporal lobe epilepsy treated with anterior temporal lobectomy (ATL). The majority of the patients with medically refractory focal epilepsy had Quality of Life in Epilepsy-89 (QOLIE-89) assessment at the time of prolonged video/EEG monitoring as part...
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Epidemiological studies of Alzheimer's disease and dementia are often two-phase studies including a screening phase and a clinical assessment phase. It is common to interview a relative of the subject at each of these phases to obtain information about the subject's exposure to risk factors. This can result in a misclassification error when assessi...
Article
Full-text available
The relation between trace element levels in drinking water and cognitive function was investigated in a population-based study of elderly residents (n = 1, 016) in rural China in 1996–1997. Cognitive function was measured using a Chinese translation of the Community Screening Interview for Dementia. A mixed effects model was used to evaluate the e...
Article
A significant interaction among total serum cholesterol (TC), APOE genotype, and AD risk was found in a population-based study of elderly African Americans. Increasing TC was associated with increased AD risk in the group with no epsilon4 alleles, whereas TC was not associated with increased AD risk in the group with one or more epsilon4 alleles. F...
Article
To estimate the reproducibility of computerized measurements of minimum joint space width (JSW) in the medial tibiofemoral compartment in knee radiographs (semiflexed AP view) obtained from clinical radiology units. Technologists from 5 clinical radiology units were trained in the performance of the fluoroscopically assisted semiflexed AP knee exam...

Citations

... Massage therapy with duration ≥5 weeks had benecial immediate effects on improving pain, anxiety, and depression in patients with bromyalgia [19]. While, another pilot study suggest modest benets to FM patients at four weeks which is not signicant at later time-points [20]. So, there are fewer and contraindicatory ndings about the benecial effect of massage therapy in bromyalgia. ...
... Further research is needed to properly understand Fl concentration levels and accumulation levels, though. Numerous studies have demonstrated that both premenopausal and postmenopausal women who live in areas with higher Fl exposure lose their radial bones at a higher rate (Helte et al., 2021;Li et al., 2001;Sowers et al., 1991). ...
... Previous optical imaging studies have also indicated that astrocytic calcium signaling may be involved in neurovascular vessel dilation contributing to a positive BOLD fMRI signal [7,12,29]. In an epidemiological study, it was shown that calcium in drinking water has protective effects on cognitive decline in older persons (age > 65 years), depending on the given dosage [6]. This effect was measurable at 86 mg/l calcium in the drinking water, but in higher calcium doses, the effect disappeared. ...
... Computer-assisted automated methods for analyzing osteoarthritis (OA) and RA in knee regions using both X-ray and thermal imaging modalities have been implemented in the literature. [12][13][14][15][16][17][18] Stachowiak et al. 19 developed an automated method for analyzing the trabecular bone X-ray images of knee and hand regions for the detection of OA and performed the fractal signature method for texture analysis. Subramaniam et al. 20 described a computer-aided diagnosis method using statistical feature extraction and SVM classifier for classification of OA. ...
... This could be explained by: (1) the relatively smaller sample in this subgroup (n = 486 patients) compared to the high-risk and general population subgroups (n = 1457 and 8820 participants, respectively); (2) the shorter followup period in Staekenborg et al. (2009) (average=1.8 years) compared to other studies, the shorter follow-up period might not be sufficient for dementia to manifest; (3) Staekenborg et al. (2009) did not report their participants' baseline vascular risk factors. These factors have been reported in many studies as important risk factors for dementia as hypertension (Skoog et al., 1996;Starr et al., 1993;Bellew et al., 2004), smoking (Shinton and Beevers, 1989;Ott et al., 1998;Merchant et al., 1999;Tyas et al., 2003), diabetes (Brands et al., 2005;Young et al., 2006), and hyperlipidemia (Maki et al., 2005;Evans et al., 2000;Moroney et al., 1999); (4) Both studies in the memory clinic subgroup did not report the baseline APOE status of their participants, unlike the other groups. APOE is considered a principal risk factor for dementia development (Saunders et al., 1993;Blacker et al., 1997;Martins et al., 2005;Duron and Hanon, 2008); and (5) Different outcome measures for dementia were used in the follow-up. ...
... 50 For example, several studies have found that attaining Engel class I (the overarching "seizure freedom" class encompassing several seizure states) is associated with a worsening QoL; this is not true, however, for those who attain the subclass Engel 1a ("completely seizure free since surgery"). 41,51,52 This decline in QoL for the broad Engel class I may be underpinned by confounding factors such as failure to attain patients' expectations before surgery, including hoping to be "cured" and stop ASMs, 53 and the need to change ASM number or dosage, with the corresponding ASM side effects. ...
... There were no refusals. Since there were outreach activities by employees from the county offices of the Chinese Center for Disease Control to prepare each community for the surveys, no refusal was not surprising and it was not unusual for studies conducted in rural China, as reported in our pilot study [11] and a large dementia prevalence study [12]. However, a few subjects with hearing problems were not enrolled. ...
... In Table 1, we detail the tests included in HCAP and the domain to which they were assigned. The HCAP includes items from brief mental status tests including the Mini-Mental State Examination (MMSE) (Folstein et al. 1975), the Telephone Interview for Cognitive Status (TICS) (Brandt et al. 1988), and the Community Screening Instrument for Dementia (CSI-D) (Hall et al., 2000;Hall et al., 1993). Elements from neuropsychological tests and batteries are also included. ...
... Many studies have tried to answer the question of whether antihypertensive agents can prevent or slow down AD. There is a wealth of observational studies showing that the use of antihypertensive therapy is associated with a lesser incidence or prevalence of cognitive impairment and dementia [10][11][12][13][14][15][16]. With the exception of the Rotterdam Study cohort, where the decrease of the relative risk for AD was not significant [12], most studies yielded the same results when separating AD from all-type dementia [10,[12][13][14][15][16]. ...
... This study included 991 participants. There were 217 people in the cognitive impairment group, with a cognitive impairment rate of 21.9%, which is higher than the prevalence of mild cognitive impairment of 15.5% among Chinese elderly people [16], and the 10.8% prevalence of cognitive impairment in the Canadian older adult population reported by Chihireh B et al. [18], but lower than the prevalence of 23.4% reported by Unverzagt FW et al. in an elderly African American population [19]. The differences may be due to the different methods currently used to assess cognitive function status, inconsistent criteria for determining cognitive impairment, the slightly different incidence of cognitive impairment in different regions, or the differences due to genetic characteristics, local natural environment, dietary characteristics, and gene-environment interactions in different study populations in different regions. ...