Cheng-I Liao’s research while affiliated with Taichung Veterans General Hospital and other places

... One study at Hospital Melaka in Malaysia reported that 44.8% of cases diagnosed were premenopausal women and as much as 16% of EC cases were diagnosed in women <40 years old [2]. In the United States, the incidence of EC in black women aged 35-49 years has increased by 2.8% per year from 2001 to 2019 [11]. ...

Reference:

Endometrial Cancer in Reproductive-Aged Females: Etiology and Pathogenesis

... Considering that we included several Japanese cohorts in our review, we can argue that the increased prevalence of p53 mutations found in G3 endometrial carcinoma corroborates this fact. Data on regional differences in endometrial cancer are evolving, and there is a need to adjust studies to the molecular classification of endometrial carcinomas [79]. ...

Reference:

Abnormal p53 High-Grade Endometrioid Endometrial Cancer: A Systematic Review and Meta-Analysis

... Failure to meet target HPV vaccination rates among adolescents in communities served by safety-net clinics is of particular concern, as these are the same communities that experience a disproportionate burden of cervical and other HPV-associated cancers. The implementation of evidence-based strategies (EBS) to improve HPV vaccination within safety-net clinics is critical to addressing long-term cancer inequities [9][10][11][12]. ...

Reference:

Use of concept mapping to inform a participatory engagement approach for implementation of evidence-based HPV vaccination strategies in safety-net clinics

... Endometrial cancer incidence was adjusted for hysterectomy prevalence and age adjusted to the 2000 US standard population. As hysterectomy data were only available on even-numbered years from 2000 to 2022 for all jurisdictions, we estimated the hysterectomy prevalence for odd-numbered years by averaging their adjacent even-numbered years using similar methods described elsewhere [21,22]. For example, we estimated the hysterectomy prevalence in 2021 by averaging the prevalence in 2020 and 2022. ...

Reference:

Trends in Endometrial Cancer Incidence Among Premenopausal and Postmenopausal Women in the United States Between 2001 and 2021

... In 2019, Utah had the highest incidence of distant melanoma among white women, with an incidence rate of 3.45 cases per 100,000. 24 This high incidence aligns with broader trends in the United States, where melanoma incidence has been rising, particularly among older adults. 25 The high prevalence in Hawaii and Utah may be related to lifestyle factors that increase Ultraviolet (UV) exposure, such as outdoor activities and tanning habits. ...

Reference:

Age-period-cohort Analysis of Cutaneous Malignant Melanoma Incidence in the United States from 1987 to 2016

... Upper urinary tract urothelial carcinomas (UTUCs), including renal pyelocaliceal and ureteral cancers, are part of the broader category of urothelial cancers (UCs) alongside bladder cancers (BCs). In Western countries, UTUCs represent 5-10% of UCs (1), and in East Asia, their prevalence can reach up to 43% due to the use of aristolochic acid in herbal medicine (2)(3)(4)(5). These carcinomas are characterized by their deep location and insidious onset, complicating early detection. ...

Reference:

Diagnostic status and new explorations in upper urinary tract urothelial carcinoma: a literature review

... National Cancer Institute) to evaluate trends of AAMRs in each subgroup. This method, as described in previous similar studies, determines the significance of AAMR changes over time using log-linear regression models where temporal variation occurred [20,21]. Annual Percent Change (APC) with 95% confidence intervals (CI) for the AAMRs was calculated using the Monte Carlo permutation test at the identified line segments linking joinpoint. ...

Reference:

Cardiovascular mortality trends and disparities in U.S. breast cancer patients, 1999–2020: a population-based retrospective study

... Cervical and ovarian cancers, in particular, are notable causes of death worldwide [1][2][3]. While most endometrial cancers are diagnosed at early stages, mortality rates have been increasing since 1997 [4]. Treatment for gynecologic malignancies remains a scientific priority, and the development of effective novel treatments in the persistent, advanced, and recurrent settings is needed [5]. ...

Reference:

Recent Therapeutic Advances in Gynecologic Oncology: A Review

... Several studies have identified these disparities in accessing cervical cancer screening. For instance, a study conducted in the USA (Chan et al., 2022) revealed that 13.6% (n total= 324) of transgender men had never undergone cervical cancer screening, compared to 5.7% (n total= 201061) of cisgender women (p < 0.01). This difference was more pronounced among younger participants, with only 50% of transgender men aged 18-29 reporting having had screening, compared to 70% of cisgender women (p = 0.011). ...

Reference:

Early detection of cervical and breast cancer in transgender and allogender individuals assigned female at birth: a scoping review

... However, regional disparities in vaccine adoption persist, and cervical cancer remains a substantial concern not only in countries where the HPV vaccine is not widely available but also in countries where the vaccine is commonly administered. For example, in the United States, survival rates have shown minimal improvement since the 1970s, and instances of stage IV advanced cervical cancer are increasing [3]. ...

Reference:

Recent advances in immunotherapy for cervical cancer