Cheng Gui-Fang's research while affiliated with Zhengzhou University and other places

Publications (5)

Conference Paper
This paper mainly deals with the exponential stability of a class of linear time-varying slow-varying systems which A(t) is continuous but not differentiable. i.e. we only require that A(t) is Lipschitz continuous. Some theorems to extend the slow-varying condition from smooth case to nonsmooth case are established. Furthermore, when the linear sys...
Article
Based on the differences between cyclooxygenase-2 (COX-2) and COX-1, a series of derivatives of naproxen in which the carboxyl group was replaced with a variety of substituted thiazolyls were designed. Seven target compounds were synthesized in four steps with naproxen as a starting material and structurally confirmed by H-1 NMR, MS and elemental a...
Article
A detection of anthracycline antitumor drug daunomycin (DNR) reacting with DNA in simulate metabolismin vitro has been made. It was found that DNR could react with DNA to form DNR-DNA adducts. The adduct compositions of DNR with fish sperm DNA and thermally denaturated DNA were determined. The equilibrium association constant K of DNR with fish spe...
Article
The liver of a two-humped camel (Camelus bactrianus) was examined by means of gross anatomy and histology. The liver appeared characteristically as an enlarged triangle in visceral aspect, and showed the following lobation: the left lateral and medial lobes, the right lobe, the caudate lobe and the quadrate lobe. These findings were similar to thos...
Article
AIM: To examine the inhibitory effect of resveratrol on matrix metalloroteinase-9 (MMP-9) and explore its mechanism. METHODS: MMP-9 activity was analyzed by gelatin zymography; MMP-9 protein was detected by Western blot; MMP-9 mRNA expression was investigated by RT-PCR. Activation of activator protein -1 (AP-1) was measured by electrophoretic mobil...

Citations

... In this study, we address these challenges experimentally using judiciously chosen selection conditions and a chemically diverse starting library of HFNAPs to acquire data of sufficient quality to train a machine learning model. These selection improvements increase enrichment efficiency, enabling the discovery of highly active sequences that bind daunomycin, a smallmolecule chemotherapeutic [31][32][33] . ...
... Fig. (2H) is a natural phytoalexin found in grapes and other plants [98]. Although resveratrol has been demonstrated to have such [99], recently it was found to have direct inhibitory effect on MMP enzyme activity, so modulation of resveratrol on MMP gene expression may be one of its anti-inflammatory mechanisms and anti-tumor activity [100,101]. These activities may have a therapeutic potential given a novel means of controlling growth and invasiveness of tumors [99]. ...
... Similar findings were also noticed by Pareek (2000) in sheep. Endo et al. (2000) observed that the liver of a two-humped camel (Camelus bactrianus) appeared characteristically as an enlarged triangle in visceral aspect. W hile Osman (2008) observed in the liver of the pig that it was divided into two independent segments, right and left. ...