Changsu Sung’s research while affiliated with Gyeongsang National University Hospital and other places

Purpose: The purpose of this paper was to translate and validate into the Korea language and setting the Sarcopenia Quality of Life (SarQoL®) questionnaire. Methods: The participants consisted of 450 individuals in Namgaram-2 cohort who were followed up in 2019-2020. The study participants were divided into four groups: (1) SARC-F < 4, (2) SARC-F ≥ 4 and robust grip strength, (3) SARC-F ≥ 4, low grip strength, robust muscle mass, (4) SARC-F ≥ 4, low grip strength, and low muscle mass. To assess construct validity, population with sarcopenia-associated symptoms (SARC-F ≥ 4) apart from the Korean SarQoL (SarQoL-K®) completed the Korean versions of two generic questionnaires, the Short Form-36 and the EuroQoL 5-dimension. To validate the Korean SarQoL®, we assessed its validity (discriminative power, construct validity), reliability (internal consistency, test-retest reliability), and floor/ceiling effects. Results: The SarQoL-K® questionnaire was translated without major difficulties. The mean SarQoL-K scores were 72.9 (95%, CI; 71.2-74.6) in SARC-F < 4, 54.6 (95%, CI; 50.7-58.3) in SARC-F ≥ 4 and robust grip strength, 47.0 (95%, CI; 43.8-50.1) in SARC-F ≥ 4, low grip strength, robust muscle mass, 46.6 (95%, CI; 43.0-50.1) in SARC-F ≥ 4, low grip strength, and low muscle mass. The results indicated good discriminative power across each four groups (p < 0.001), high internal consistency (Cronbach's alpha of 0.866), and excellent test-retest reliability (ICC = 0.977, 95% CI 0.975-0.979). No floor- or ceiling-effects were observed. Conclusions: This is the first study to confirm the reliability and validity of the Korean version of the SarQoL®. We demonstrated that the population with sarcopenia-associated symptoms (determined using the SARC-F questionnaire) has a lower quality of life.

PURPOSE: The purpose of this study was to determine whether combined exercise-mediated acquisition on the body composition, muscular strength, blood variables and physical fitness occur in female elderly aged over 80 years.METHODS: Total 63 elderly (Control group, CON, n=36; Exercise group, EXE, n=27) aged between 80 and 90 years participated in this study. EXE group performed combined exercise for an hour at a time, twice a week for 8 week.RESULTS: Body composition was not significantly changed before and after 8-week treatment in both groups. However, systolic blood pressure was increased and HDL-cholesterol was decreased in CON group. Also, muscular strengths in quadriceps femoris, biceps femoris and triceps brachii were significantly decreased in CON group, while there was no statistical change in EXE group. Fasting bloodglucose in EXE group was significantly decreased. Physical-fitness factors determined by senior fitness test were all significantly improved only in EXE group, while there was no change in CON group. These results suggest that combined exercise is very effective prescription in the super-aged elderly.CONCLUSIONS: Combined exercise is very effective prescription in the super-aged elderly. Based on our study, we propose that need to develop various programs using combined exercise for super-aged elderly.

Aim We investigated whether exercise‐mediated acquisition of muscle mass and strength would occur in a concurrent manner in older adults. Methods A total of 152 community‐dwelling older adults (young‐old aged 65–74 years, old‐old aged >75 years) were allocated into either 8‐week comprehensive exercise training or the control group. Participants (n = 136) completed all pre‐ and post‐intervention testing visits (young‐old n = 73, old‐old n = 63). Older adults in exercise groups were subjected to a series of programmed elastic band and free exercises twice per week at three to five sets of 15–20 repetitions. Body composition, skeletal muscle mass, knee strength (extensors and flexors) and gait‐related physical function were evaluated as main variables. Results As expected, muscular mass and knee strength (both extensors and flexors) were inversely correlated with age in the old‐old group (all P < 0.001). However, knee extensor strength was the only lower limb component inversely correlated with age in the young‐old group (P < 0.043). Knee extensor strength was significantly increased by exercise training in both the young‐old and old‐old groups (young old P < 0.042, old‐old P < 0.011). Training‐induced muscle hypertrophy was observed only in the young‐old group (P < 0.025). the correlation of knee extensor strength against gait‐related physical function was the greatest, followed by knee flexor strength and muscle mass. Conclusions The present results showed that age‐associated strength decline of the knee extensor occurs earlier compared with the knee flexor during the aging process, and exercise training increases muscular strength without significant changes of muscle mass in older adults aged aged ≥75 years. Geriatr Gerontol Int 2019; ••: ••–••.