Chan Wu's research while affiliated with Université de Montréal and other places

Publication (1)

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Aims: Biofilm formation is important for the persistence of bacteria in hostile environments. Bacteria in a biofilm are usually more resistant to antibiotics and disinfectants than planktonic bacteria. Our laboratory previously reported that low concentrations of zinc inhibit biofilm formation of Actinobacillus pleuropneumoniae. The aim of this st...


... Owing to the urgent need for alternative antimicrobial options, the application of combined therapy has attracted the attention of many scientists and clinicians as an effective strategy to overcome infections associated with biofilms. This approach might be addressed via the combination between conventional antibiotics and zinc as one of the trace elements which is essential for many vital processes [6] and with previously demonstrated antibiofilm efficacy [8]. Consequently, the current study aimed to explore the antimicrobial interaction pattern between zinc sulfate and different classes of antibiotics including cephalosporins, fluoroquinolones, aminoglycosides, and carbapenems against biofilm-forming K. pneumoniae. ...