Cécile Payet's research while affiliated with Claude Bernard University Lyon 1 and other places

... The fact that surgical outcomes deteriorated suggests that the hospital organizations lacked resiliency, even though we observed notable improvements from one semester to the other [36]. Stressful work conditions caused by staffing shortages, overwork and reallocation from operating rooms to ICU/IMCUs, may have compromised the wellbeing of health professionals and their routine safety practices [37][38][39][40][41]. To mitigate the heterogeneous burden of the pandemic between facilities over time, health authorities organized inter-hospital transfers of critically ill COVID-19 patients [42]. ...

... Patients were then categorized into low-or-no (< 30%), moderate (from 30 to 60%), and high-exposure (> 60%) categories using official thresholds established by the French Ministry of Health to distinguish levels of ICU/ IMCU occupancy in hospitals during the pandemic [14]. This definition of pandemic exposure considered change in exposure day by day during the study period for each hospital [15]. On the one hand, exposure of patients operated during the pandemic in 2020 corresponded to the "true exposure" they experienced during their stay. ...

... As observational studies are prone to confounding and bias, novel approaches such as propensityscore (PS) matching and high-dimensional PS analysis can be considered in future studies to overcome the inherent limitations of real-world studies, such as measured and unmeasured confounding [39,40]. Additionally, novel study designs ...

... websites. The marketing authorization of a generic drug is based on the proof of BE trials (Viprey et al., 2020), which requires manufacturers to certify that their generic pharmaceuticals are bioequivalent to brand drugs (Zhong et al., 2018), and BE trials are often executed with healthy volunteers and avoided with respect to women during pregnancy (Government of Canada, 2018). Therefore, we removed the BE trials from our analyses to discern the impact of BE on our study. ...

... The treatment of severe disease requires specialized infrastructure that is only found in large university hospitals, sometimes called tertiary care hospitals. Regionalization allows patients to get adequate care in these high-volume centers [9,10], although the relationship between volume and quality has been debated [11]. These hospitals naturally assume the role of leaders in hospital systems. ...

... Here, in Tables 28-32 for nodes 2 (Home/Private Residence), 4 (Other admission sources) and 5 (Police Custody) covariate 21 of 35 "District" and nodes 3 (Home for the Elderly) and 6 (unknown admission source) covariate "Age" offer the maximum positive gain in C-PTD. Therefore, we select this split to grow the tree, and new nodes are shown in Figure 7 as 7,12,17,22,27,32,37,42,43,49,52,57,62,67,70,75,80,81,84,87,90,92,93, 94, and 95. 57 show that only nodes 7,12,17,22,27,32,37,52,57,62,67,70,75,81,84,87 and 90 provided significant WIC improvement with a split by Age, and nodes 49, 67 and 35 provided significant WIC improvement with a split by gender and only node 43 provided significant WIC improvement with a split by District. ...

... amegroups.cn/static/public/cco-21-36-1.pdf) (85)(86)(87)(88)(89)(90)(91)(92)(93)(94)(95)(96) published in the last 2 decades, including 4 RCTs (81,83,87,88). On comparing the components (pre-, intraand post-operative) of the pathways in these studies, we found considerable heterogeneity amongst institutional protocols. ...

... However, the identification of metrics to assess accurately medical centers performance regarding bariatric surgery is still debated [13]. Postoperative mortality has been rejected because this event is too rare to allow meaningful peer-based comparisons [4,9,11,13,14]. Severe complication, defined as the need for patient reoperation following initial procedure, has been suggested as a superior indicator of safety in bariatric surgery [8,13,15]. This simple surrogate marker is clinically relevant to describe the quality of the postoperative period. ...

... We extracted the patients' demographics, comorbidities [16], frailty scores [17], emergency room admission before surgery, the date of the surgical procedure performed with the corresponding specialty and severity, ICU/IMCU admission following the surgery, patient vital status at discharge from ICU/IMCU and hospital stay, as well as the hospital status (academic, publicnot-for-profit, and private-for-profit) and location area (Greater Paris, North-East, South-East, North-West, South-West). Patient median household income was obtained from their residential codes. ...

... Nevertheless, it appears from our findings that the occurrence of major postoperative complications, other than mortality, following major large bowel resection for non-malignant colorectal polyp, detected during the evaluation of positive colorectal screening, may be similar to that following resection of CRCs overall. [22][23][24] However, postoperative mortality following major resection of non-malignant polyps among participants in the population-based screening program CCC is somewhat lower than following major resection of CRC; [25][26][27][28][29][30][31] this is also consistent with publications on major resection of non-malignant polyps which are not based on population-based screening programs. [18][19][20][21] Towards the end of this observation period, initiatives to improve the quality of major large bowel resections for CRC were introduced in Ontario. ...