Caroline Verhaeghe's research while affiliated with Unité Inserm U1077 and other places

Publications (29)

Article
Background Preterm delivery is a risk factor for sub-optimal neurodevelopment. Pregnancies conceived after medically-assisted reproduction – which includes in vitro fertilisation, with or without intracytoplasmic insemination, as well as induction of ovulation followed by intra-uterine insemination or timed intercourse – have a higher risk of prete...
Article
Introduction La prématurité est un facteur de risque de développement neurologique non optimal. Les grossesses obtenues après assistance médicale à la procréation (AMP) ont un risque plus important de prématurité. L’objectif de cette étude était d’évaluer le développement cognitif à 5,5 ans des enfants nés prématurés en fonction du mode de concepti...
Preprint
Objectives: To compare the neonatal morbidity of caesarean sections (CS) performed after conversion from neuraxial (NA) to general anaesthesia (GA) with CS performed under GA from the outset, and to assess whether the increase in DDI in urgent and extremely urgent cases with conversion from NA to GA increased the risk of neonatal morbidity. Design:...
Article
Introduction La prématurité est un facteur de risque de développement neurologique non optimal. Les grossesses obtenues après assistance médicale à la procréation (AMP) ont un risque plus important de prématurité. L’objectif de cette étude était d’évaluer le développement cognitif à 5,5 ans des enfants nés prématurés en fonction du mode de concepti...
Article
Background The conversion of neuraxial anesthesia (NA) to general anesthesia (GA) during a cesarean section (CS) may be associated with a higher risk of neonatal morbidity by adding the undesirable effects of both these anesthesia techniques. We aimed to compare the neonatal morbidity of non-elective CS performed after conversion from NA to GA (sec...
Article
OBJECTIVE This study aimed to evaluate if manual rotation, undertaken during labor, of fetuses in occiput posterior or occiput transverse position led to an increased rate of spontaneous vaginal delivery. DATA SOURCES Searches were performed in MEDLINE, Ovid, Scopus, ClinicalTrials.gov, and the Cochrane Central Register of Controlled Trials with t...
Article
Objective To validate a mathematical model to predict the mean time to delivery (TTD) following cervical ripening with dinoprostone vaginal insert (DVI), and assess its impact on the risk of nocturnal deliveries. Methods We performed a case-control retro-prospective study at Angers University Hospital. In the control group, we retrospectively incl...
Article
Objective: To evaluate whether manual rotation of fetuses in occiput posterior positions at full dilation increases the rate of spontaneous vaginal delivery. Methods: In an open, single-center, randomized controlled trial, patients with a term, singleton gestation, epidural analgesia, and ultrasonogram-confirmed occiput posterior position at the...
Article
Objectives : The objective of this study was to identify the factors predictive of the success of external cephalic version (ECV). Methods : A single-centre retrospective observational study was performed in the maternity ward of the Angers University Hospital, France, between January 2010 and May 2020. The study included all patients (n=613) for...
Article
Full-text available
Background The learning curve cumulative summation test (LC CUSUM test) allows to define an individualized learning curve and determine the moment when clinical proficiency is attained. After acquisition of the skills, the cumulative summation test (CUSUM test) allows to monitor the maintenance of the required level over time. The LC CUSUM test has...
Article
The question of pregnancy prognosis after radio chemotherapy is unaddressed. We report here the case of three successive spontaneous pregnancies 17 years after the management of a thigh rhabdomyosarcoma treated by radiochemotherapy. In 2018 the patient aged 22 presented with a spontaneous miscarriage. In 2019, she obtained a new spontaneous pregnan...
Article
Objectives To investigate the perinatal outcomes of women with a history of female genital mutilation (FGM) who underwent clitoral reconstruction (CR) compared with women with FGM who did not undergo CR. Material and methods Retrospective case-control study at Angers University Hospital, between 2005 and 2017. Inclusion criteria: pregnant women >1...
Article
The aim of this study was to evaluate an oocyte pick-up (OPU) simulation training program for residents using the high fidelity PickUpSimTM (Accurate, Cesena, Italy) simulator. The authors carried out an observational study during an OPU simulation workshop. A successful scenario was defined as an oocyte retrieval rate ≥70% without any complication...
Article
Purpose To determine the risk of multiple pregnancies (MP) following conversion of in vitro fertilization (IVF) cycles to intrauterine insemination (IUI) when a poor ovarian response (POR) is diagnosed during controlled ovarian stimulation (COS). Methods We undertook a retrospective study in our teaching hospital from January 2012 to December 2017...
Article
Full-text available
The objective was to compare the endometrial thickness (ET) in a frozen embryo transfer (FET) cycle between transdermal and vaginal estrogen. Our secondary objectives were to compare the patient satisfaction and the pregnancy outcomes. Prospective monocentric cohort study between 01/2017 and 12/2017 at a single institution. Choice of administration...
Article
Full-text available
Objective To evaluate the use of new bipolar vessel sealing system like LigaSure™ compared to the standard surgical technique (suture) during emergency peripartum hysterectomy (EPH). Methods A retrospective observational bicentric study was conducted from February 2005 to August 2018 in the maternity wards of the University Hospital of Toulouse an...
Article
Objective: Our study aimed to assess the impact of a simulation training program for residents for the disclosure of diagnosis on the psychological experience of couples following a first trimester pregnancy loss (PL). Methods: We performed an uncontrolled prospective single center, before-after study, at the gynecological emergency department o...
Article
The rupture of the ureter during pregnancy is a rare complication and is most frequently observed in the right ureter. We report below the case of a rupture in the left ureter. A 36-year old woman gave birth vaginally to a 3010-g girl without operative vaginal delivery or episiotomy. The following day, the patient exhibited a sudden pain in the lef...
Article
Full-text available
Background: The frequency of posterior presentations (occiput of the fetus towards the sacrum of the mother) in labor is approximately 20% and, of this, 5% remain posterior until the end of labor. These posterior presentations are associated with higher rates of cesarean section and instrumental delivery. Manual rotation of a posterior position in...
Article
The development of video tutorials is flourishing and may make it possible to maintain knowledge learned during instruction with simulation. The aim of this study was to assess the effect of adding a video tutorial to a lecture and simulation for learning the maneuvers and protocol for the management of shoulder dystocia.Student midwives and medica...

Citations

... ECV is usually performed before the active labor period begins. Factors associated with a higher ECV success rate include the following [3][4][5][6]: multiparity, a transverse presentation, black race, posterior placenta, and amniotic fluid index higher than 10 cm. ...
... Characteristics of the 6 studies included in the meta-analysis are shown in Table 1. All included studies compared prophylactic (eg, before any diagnosis of dystocia) rotation of OP or OT fetuses, all confirmed with ultrasound examination, during the second stage of labor with either no procedure 16,19,21 or a sham rotation procedure. 14,15,20 One study used digital rotation only, 14 1 study used the Tarnier and Chantreuil technique, 19 and the remaining 4 studies allowed the operator to use a variety of techniques. ...
Reference: Manual Rotations
... However, outcomes of CR on orgas-mic function are ambiguous, as authors of other studies on CR have reported improved orgasmic function [44]. Only one study investigated obstetric outcomes after CR [49]. Here, conducting a case-control study with 84 women (28 in the CR group and 56 in the control group), the authors found that CR reduced the risk of episiotomy during childbirth (29.54%) compared to the control group (63.6%) [49]. ...
... The authors concluded that simulationbased training could be useful in the initial part of training, allowing residents and fellows to reach a predefined level of performance before operating on real patients. We recently performed an observational study [24] during a simulation workshop that included 46 residents from 23 different university hospitals. All residents found the training beneficial, and 87% were in favor of introducing it on the training program. ...
... With the constant advancements of the level of assisted reproductive technology, highquality embryo obtainment is no longer a clinical problem. Nevertheless, the pregnancy rate of patients remains less than satisfactory, mainly due to poor endometrial receptivity [3,4]. Since the success of frozen-thawed human embryo transfer in Australia in 1983, frozen-thawed embryo transfer (FET) technology has been widely used in the field of human Assisted Reproductive Technology (ART) due to its high cumulative pregnancy rate. ...
... A 25-step technique for radical cesarean hysterectomy has been demonstrated to result in lower blood loss and lower intensive care unit admissions [35]. Bipolar electrocautery compared to surgical sutures and use of topical hemostatic agents may further lower blood loss during peripartum hysterectomy [36,37]. Lastly, pelvic packing may be required in the event of intractable PPH after peripartum hysterectomy due to coagulopathy. ...
... Seven studies had a distress protocol in place due to the sensitiveness of the topic [5,20,30,31,[45][46][47]. Conversely, twenty-three did not mention if they had such protocol in place [6,[21][22][23][24][25][26][27][28][29][32][33][34][35][36][37][38][39][40][41][42][43][44]. Sixteen studies declared they had no conflict of interest [5, 20-22, 28, 29, 33, 35, 37, 40-43, 45-47] and fourteen did not mention this [5, 6, 23-26, 30-32, 34, 36, 38, 39, 44]. ...
... Spontaneous ureteral injury, defined as injury which occurs in the absence of any interventional procedure, external trauma or surgery, is a rare cause of acute abdominal pain. Intrapartum rupture of the ureter is an uncommon complication and in the absence of known renal pathology is particularly rare [1]. Complications of ureteral rupture include urinoma, abscess and sepsis [1]. ...
... Immunomodulatory treatments have also been tested in clinical trials. Topical imiquimod, which induces interferon alpha (IFN)-α production upon binding to Toll-like receptor 7 (TLR7), has shown benefit in the treatment of BLT [40][41][42][43]. Interestingly, Geusau et al. ...
... Two randomized controlled trials, each with a similar sample size to the POP-OUT Trial, are currently being conducted in France. 37,38 Future metaanalyses will provide further information about the possible benefits or harms of prophylactic manual rotation, particularly with regard to the prevention of instrumental births, and may provide more information about the impact of investigator experience. Based on our posthoc analysis, it would be useful to report results by flexion or deflexion of the fetal head. ...