Carolien Thush’s research while affiliated with Maastricht University and other places

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Publications (21)


Figure 1. Latent growth model for the log alcohol use index. Condition = control or experimental group; Intercept = baseline log alcohol use index; Slope = change log alcohol use index; Log Drink Pretest = log alcohol use index score at pretest; Log Drink Posttest = log alcohol use index score at posttest; Log Drink FU = log alcohol use index score at six month follow up. The labels mark path coefficients that were constrained across assessment points. By fixing all paths from the intercept factor to each measurement point to 1 and all paths from the slope factor to each measurement point to 0, 4, 26 (representing the number of weeks between time points), this model represents linear growth. The path from condition to intercept tests whether the experimental group differs from the control group in baseline functioning. This is the main effect of condition. The path from condition to slope tests whether individual growth within the experimental group differs from individual growth in the control group. This is the interaction between time and condition we are primarily interested in evaluating. Both the variance U1 and the covariance between U0 and U1 were fixed at 0 to make the model admissible (these values were estimated negative if not fixed). The variances of the latent variables d1–d3 were estimated equal to each other; the model  
Influence of Motivational Interviewing on Explicit and Implicit Alcohol-Related Cognition and Alcohol Use in At-Risk Adolescents
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March 2009

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107 Reads

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48 Citations

Carolien Thush

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Both implicit and explicit cognitions play an important role in the development of addictive behavior. This study investigated the influence of a single-session motivational interview (MI) on implicit and explicit alcohol-related cognition and whether this intervention was successful in consequently decreasing alcohol use in at-risk adolescents. Implicit and explicit alcohol-related cognitions were assessed at pretest and one month posttest in 125 Dutch at-risk adolescents ranging in age from 15 to 23 (51 males) with adapted versions of the Implicit Association Test (IAT) and an expectancy questionnaire. Motivation to change, alcohol use and alcohol-related problems were measured with self-report questionnaires, at pretest, at posttest after one month, and at the six-month follow-up. Although the quality of the intervention was rated positively, the results did not yield support for any differential effects of the intervention on drinking behavior or readiness to change at posttest and six-month follow-up. There were indications of changes in implicit and explicit alcohol-related cognitions between pretest and posttest. Our findings raise questions regarding the use of MI in this particular at-risk adolescent population and the mechanisms through which MI is effective. (PsycINFO Database Record (c) 2009 APA, all rights reserved).

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Een dubbele kijk op minder drinken. De invloed van expliciete en impliciete alcoholgerelateerde processen en vroege interventie bij jongeren

October 2008

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49 Reads

Psychologie & gezondheid

A double perspective on drinking less: The influence of explicit and implicit cognitive processes and early intervention in adolescents Alcohol use among Dutch adolescents is a serious problem. Dual process models of addiction state that both implicit and explicit cognitive processes influence (early) adolescent drinking behavior. Where implicit cognitive processes represent more automatic associative motivational processes, explicit cognitive processes are related to more deliberate thought processes. The relationship between alcohol-related cognition and adolescent alcohol use is assumed to be moderated by other factors, such as executive functioning and motivation. This implicates that different intervention methods might be effective for different subgroups of at-risk adolescents. The present paper discusses the current state of affairs in intervention research from a dual process perspective.


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Working Memory Capacity Moderates the Predictive Effects of Drug-Related Associations on Substance Use

September 2008

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111 Reads

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203 Citations

Some theories suggest that spontaneously activated, drug-related associations in memory may have a "freer reign" in predicting drug use among individuals with lower working memory capacity. This study evaluated this hypothesis among 145 at-risk youth attending continuation high schools (CHS). This is the 1st study to evaluate this type of dual-process interaction in the prediction of drug use among a sample of at-risk adolescents. The CHS students completed assessments of drug-related memory associations, working memory capacity, and drug use. Control variables included age, gender, ethnicity, and acculturation. Robust multiple regression using least trimmed squares estimation indicated that there was a significant linear by linear interaction between working memory capacity (assessed with the self-ordered pointing task) and drug-related associations (assessed with verb generation and cue-behavior association tasks) in the prediction of alcohol and cigarette use. Consistent with dual-process cognitive theories, drug-related associations in memory predicted drug use more strongly in students with lower levels of working memory capacity. These findings add to the literature implicating the influence of dual cognitive processes in adolescent risk behaviors.


Prevention of Alcohol Problems in Dutch Youth

July 2008

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45 Reads

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10 Citations

Evaluation & the Health Professions

Binge drinking among young people is a problem in the Netherlands. This article outlines the current Dutch approach to alcohol prevention in this target group. It is argued that well-enforced evidence-based control measures are lacking despite renewed political interest in them. Politicians often favor alcohol education, but to increase the effectiveness of alcohol prevention, a combined approach of policy measures, enforcement, and education is needed. Translation of education and policy-based measures is discussed.


Interactions between implicit and explicit cognition and working memory capacity in the prediction of alcohol use in at-risk adolescents

May 2008

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101 Reads

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252 Citations

Drug and Alcohol Dependence

Dual process models of addiction suggest that the influence of alcohol-related cognition might be dependent on the level of executive functioning. This study investigated if the interaction between implicit and explicit alcohol-related cognitions and working memory capacity predicted alcohol use after 1 month in at-risk youth. Implicit and explicit alcohol-related cognitions were assessed in 88 Dutch at-risk adolescents ranging in age from 14 to 20 (51 males) with an adapted version of the Implicit Association Test (IAT) and an expectancy questionnaire. Working memory capacity was assessed using the computer-based version of the Self-Ordered Pointing Task (SOPT). Alcohol use and alcohol-related problems were measured at baseline and after 1 month with self-report questionnaires. The hierarchical regression analysis showed that both the interaction between implicit positive-arousal cognitions and working memory capacity and the interaction between explicit positive-arousal cognitions and working memory capacity predicted unique variance in alcohol use after 1 month. Implicit positive-arousal cognitions predicted alcohol use after 1 month more strongly in students with lower levels of working memory capacity, whereas explicit positive-arousal cognitions predicted 1-month follow-up alcohol use more strongly in students with higher levels of working memory capacity. This could imply that different intervention methods could be effective for different subgroups of at-risk youth.




Apples and Oranges? Comparing Indirect Measures of Alcohol-Related Cognition Predicting Alcohol Use in At-Risk Adolescents

December 2007

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18 Reads

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70 Citations

Recently, there has been increased interest in the role of implicit cognitive processes in the development of addictive behaviors. In this study, the authors compared 3 indirect measures of alcohol-related cognitions in the prospective prediction of alcohol use in at-risk adolescents. Implicit alcohol-related cognitions were assessed in 88 Dutch at-risk adolescents ranging in age from 14 to 20 years (51 males, 37 females) by means of varieties of word association tasks, Implicit Association Tests, and Extrinsic Affective Simon Tasks adapted for alcohol use. Alcohol use and alcohol-related problems were measured with self-report questionnaires at baseline and after 1 month. Results showed that the indirect measures predicted unique variance in prospective alcohol use after controlling for the direct measure of alcohol-related cognitions and background variables. The results indicate that the word association tasks were the best indirect measure of alcohol-related cognitions. These indirect measures appear to assess cognitive motivational processes that affect behavior in ways not reflected by direct measures of alcohol-related cognitions.


Explicit and implicit alcohol-related cognitions and the prediction of future drinking in adolescents

August 2007

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64 Reads

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163 Citations

Addictive Behaviors

Both implicit and explicit alcohol-related cognitions might play a role in the early development of addictive behaviors. In this study, the association between both current and prospective alcohol use and implicit and explicit alcohol-related cognitions were measured in two different adolescent age groups (N=100; 51 twelve year olds, 49 fifteen year olds). Alcohol-related cognitions were measured on two dimensions (valence and arousal). A new measure, the unipolar Single Target Implicit Association Test (ST-IAT), was used as the implicit measure. A unipolar expectancy questionnaire was used as the explicit measure. Current alcohol use and alcohol use after one year were measured with an alcohol use questionnaire. Abstainers and drinkers differed in both their explicit and implicit alcohol-related cognitions moderated by age and gender. Additionally, a hierarchical regression analysis showed that implicit associations with alcohol added significantly to the prediction of prospective binge drinking, when controlling for grade, gender and explicit alcohol expectancies These results indicate the importance of taking implicit alcohol-related cognitions into account when intervention methods are developed.


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Comparison of Indirect Assessments of Association as Predictors of Marijuana Use Among At-Risk Adolescents

April 2007

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84 Reads

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76 Citations

In this study, the authors compared indirect measures that attempt to quantify the level of marijuana associations among adolescents. They also evaluated whether these various methods overlap or tap different aspects of associative processes that may act in concert to influence marijuana use. Automatic drug-relevant associations were assessed in 121 at-risk youth in continuation high schools in California with the use of a word association index and computer-based, reaction time measures (i.e., Implicit Association Test [IAT] and Extrinsic Affective Simon Task [EAST]). Measures of working memory capacity, sensation seeking, and explicit cognitions also were included in analyses as potential confounders. The word association index and the marijuana IAT excited D measure were significant predictors of marijuana use. The word association index accounted for more variance in marijuana use than did the IAT or EAST measures. Further, confirmatory factor analytic models of the indirect measures of marijuana use revealed a significant moderate correlation between the EAST Excitement and Word Association factors but no significant correlations between the Word Association and IAT factors. These findings suggest that there is some convergence among the different indirect measures, but these assessments also appear to tap different aspects of associative processes. The types of indirect measures evaluated in this work provide information about spontaneous cognitions related to substance use, capturing influences on behavior that are not evaluated with traditional explicit assessments of behavior. Findings from this work add to a growing body of research that implicates the importance of implicit associative processes in risk and health behaviors.


Citations (14)


... [11] Various studies have assessed the role of social skills for the prevention and/or treatment of substance dependence, some studies have positive results and some have failed. [9,[12][13][14] Social skills as one of the most impressive parts help adolescents improve their self-care and psychological comfort. Furthermore, social skills provide the conditions to modulate the emotions, control the violence, improve the individual and social competencies, make the appropriate decisions and resist against the social conflicts. ...

Reference:

The Role of Social Skills in the Prevention of Drug Addiction in Adolescents
Can problematic alcohol use be trained away? New behavioural treatments aimed at changing and moderating implicit cognitive processes in alcohol abuse
  • Citing Article
  • January 2008

... This results in hypersensitivity to the rewarding properties of substances. Substance cues become highly salient and may bias behaviour towards substance use in a rather automatic way: increasing craving, grabbing attention and activating approach behaviour (Houben, Schoenmakers, Thush, & Wiers, 2008;Van Deursen, Salemink, Schoenmakers, & Wiers, 2009;Wiers et al., 2007). Cognitive control processes are thought to inhibit the effects of these so-called motivational processes on substance use and appear to be weaker in individuals with substance use disorder (SUD) Houben & Wiers, 2009;Peeters et al., 2012), thereby further supporting continued substance use and relapse. ...

Impliciete cognitie en verslaving: Theoretische inzichten en praktische toepassingen

... The results indicated that NU also was associated with lower E-WMC, which is consistent with studies of the association between global selfreport measures of impulsivity and E-WMC ( Gunn & Finn, 2013;Khurana et al., 2012). The finding that NU is associated with higher FA rates only for those with low E-WMC is similar to other studies reporting that drug specific impulsive processes are associated increased substance use only for those with low working memory capacity ( Grenard et al., 2008;Thrush et al., 2007Thrush et al., , 2008). Although Grenard et al. and Thrush et al. used refined measures of impulsive tendencies specific to substance use, while we employed a trait measure of a specific dimension of impulsivity, these studies demonstrate the key role that E-WMC plays in behavioral regulation and modulating impulsive tendencies. ...

Comparing implicit measures of alcohol-related cognition predicting alcohol use in at-risk adolescents
  • Citing Article
  • January 2006

... Standard psychotherapy approaches typically engage explicit, top-down regulatory strategies in the service of reducing alcohol use, (e.g., Cognitive-Behavioral Therapy for substance use disorders [24]). Devising interventions that more directly engage bottom-up, automatic processes holds promise for improving clinical efficacy of available interventions targeting both components thought to drive addiction [25,26]. ...

Influence of Motivational Interviewing on Explicit and Implicit Alcohol-Related Cognition and Alcohol Use in At-Risk Adolescents

... At the same time, WM deficits have been found in dopamine-deficient groups such as addicts [9][10][11]. Specifically, at the behavioral level, addicts with poorer WM performance showed stronger cue-evoked cravings than those with higher WM performance [12]. At the neural level, it has been suggested that the stronger the activation in WM-relevant brain regions (the frontal-parietal network) under the WM task is, the lower the relapse rate after withdrawal from alcohol will be [13]. ...

Working Memory Capacity Moderates the Predictive Effects of Drug-Related Associations on Substance Use

... The harmful use of alcohol is especially fatal for younger age groups (WHO 2011). Alcohol is the first substance used during adolescence, and its use is often associated with progressive experimentation with other illicit drugs (Stewart et al. 2005). ...

New Developments in Prevention and Early Intervention for Alcohol Abuse in Youths
  • Citing Article
  • March 2005

... This was not the focus of our study because, in online studies, interventions often lead to non-specific self-reported change in drinking, with little or no differential treatment effects [24]. Indeed, Experiment 1 revealed a significant reduction in alcohol drinking in the ABC-training but also in the control-training group and a (weak) effect of the type of training was only observed in Experiment 2. This could relate to the specific (online) sample [57], but also the low number of training sessions, or the sensitivity of the measure [58,59]. Note further that beneficial changes over time in the control-training condition were also observed for outcome expectancies, self-efficacy, and craving. ...

A randomized clinical trial of a targeted intervention to moderate alcohol-related problems in at-risk adolescents
  • Citing Article
  • March 2007

Pharmacology Biochemistry and Behavior

... However, this process is often influenced by top-down cognitive processing mechanisms, namely, the controlled "reflective" system (Wilcockson & Pothos, 2015). This suggests that the controlled "reflective" system can influence substance users' attention bias toward substancerelated cues (Wiers et al., 2007;Wiers & Stacy, 2006). ...

Automatic and controlled processes and the development of addictive behaviors in adolescents: A review and a model
  • Citing Article
  • March 2007

Pharmacology Biochemistry and Behavior

... In addition to deliberate attitudes and intentions, attitudes that operate at an automatic cognitive level may be relevant in SAIC. Automatic cognitions, assessed with the help of indirect measures, have been found to predict behavior in various fields of human functioning, including sexual functioning (e.g., [44]), condom (non-)use [45,46], aggressive behavior [47], alcohol use (e.g., [48]), physical activity [49], and psychopathology (e.g., [50]). There is broad consensus that measuring implicit associations is able to bypass introspective access and socially desirable biases [51]. ...

Explicit and implicit alcohol-related cognitions and the prediction of future drinking in adolescents
  • Citing Article
  • August 2007

Addictive Behaviors

... Adolescents' participation in motivational interviewing was shown to have an impact on reducing their risk of substance. (Grenard, Ames, Wiers, Thush, Alan, & Sussman, 2007). Studies out of Jamaica show that while they have signed on to the convention of World Health Organization Framework Convention for Tobacco Control (FCTC), there is a cry for still more to be done to protect their adolescents, like advertising, branding and public display or use of cigarette has not been banned (Muula, Siziya, & Rudatsikira, 2008). ...

Brief Intervention for Substance Use among At-Risk Adolescents: A Pilot Study
  • Citing Article
  • March 2007

Journal of Adolescent Health