C.H. Waddington’s scientific contributions

What is this page?


This page lists works of an author who doesn't have a ResearchGate profile or hasn't added the works to their profile yet. It is automatically generated from public (personal) data to further our legitimate goal of comprehensive and accurate scientific recordkeeping. If you are this author and want this page removed, please let us know.

Publications (1)


The strategy of the genes: A discussion of some aspects of theoretical biology
  • Book

April 2014

·

696 Reads

·

1,419 Citations

C.H. Waddington

First published in 1957, this essential classic work bridged the gap between analytical and theoretical biology, thus setting the insights of the former in a context which more sensitively reflects the ambiguities surrounding many of its core concepts and objectives. Specifically, these five essays are concerned with some of the major problems of classical biology:the precise character of biological organisation, the processes which generate it, and the specifics of evolution. With regard to these issues, some thinkers suggest that biological organisms are not merely distinguishable from inanimate ‘things’ in terms of complexity, but are in fact radically different qualitatively: they exemplify some constitutive principle which is not elsewhere manifested. It is the desire to bring such ideas into conformity with our understanding of analytical biology which unifies these essays. They explore the contours of a conceptual framework sufficiently wide to embrace all aspects of living systems.

Citations (1)


... [18,19] It is thus possible to examine development, as well as its robustness, from two perspectives. In the first, cellular states, such as single-cell transcriptomes, were recorded during various developmental stages and used to construct a continuum of states known as an epigenetic landscape [20,21] or state manifolds. [18] In the second, all cell divisions since the zygote or some progenitor cells can be recorded and used to construct a cell lineage tree (CLT). ...

Reference:

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development
The strategy of the genes: A discussion of some aspects of theoretical biology
  • Citing Book
  • April 2014