January 2016
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64 Reads
The present study deals with the formulation of fast dissolving tablets by direct compression method using Ciprofloxacin HCL. The influence of superdisintegrants on the croscarmellose sodium and sodium starch glycolate on dissolution time, wetting time etc were studied. The prepared tablets were evaluated for weight variation, content, hardness, friability, thickness, diameter and In vitro disintegrants such as croscarmellose sodium and sodium starch glycolate are used in combinations with the drug, and the combination containing 60 mg of croscarmellose sodium and 60 mg of sodium starch glycolate showed faster dispersion time and maximum drug release in 14 min. � 2016, Annamacharya College of Pharmacy. All rights reserved.