Brynn Taylor’s scientific contributions

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Publications (3)


Figure 2. Mortality Rates for White and Black Women in the United States Between 1975 and 2006 (Horner, 2009) 
Figure 3. Complexity of Breast Cancer Causation Note: Lines indicate some of the many links among risk factors, exposures, and breast cancer. 
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State of the Evidence: The Connection Between Breast Cancer and the Environment
  • Literature Review
  • Full-text available

January 2009

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995 Reads

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131 Citations

International Journal of Occupational and Environmental Health

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Nancy Evans

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Brynn Taylor

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[...]

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Marisa Walker

A substantial body of scientific evidence indicates that exposures to common chemicals and radiation, alone and in combination, are contributing to the increase in breast cancer incidence observed over the past several decades. Key recurring themes in the growing scientific literature on breast cancer and environmental risk factors are: (a) the importance of understanding the effects of mixtures and interactions between various chemicals, radiation and other risk factors for the disease; and (b) the increasing evidence that timing of exposures matters, with exposures during early periods of development being particularly critical to later risk of developing breast cancer. A review of the scientific literature shows several classes of environmental factors have been implicated in an increased risk for breast cancer, including hormones and endocrine-disrupting compounds, organic chemicals and by-products of industrial and vehicular combustion, and both ionizing and non-ionizing radiation.

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TABLE 1 Air Contaminants Associated with Breast Carcinogenesis 
TABLE 2 Pesticides Associated with Breast Cancer 
TABLE 3 Plastics and Breast Cancer* 
TABLE 4 Household Cleaning Products and Human Health Concerns 
TABLE 5 Cosmetics and Breast Cancer 
Policy and Research Recommendations Emerging from the Scientific Evidence Connecting Environmental Factors and Breast Cancer

January 2009

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320 Reads

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11 Citations

International Journal of Occupational and Environmental Health

A substantial body of evidence links environmental exposures to increases in breast cancer incidence over the past decades. State and federal legislative initiatives that could help prevent breast cancer include: federal standards to achieve consistency in radiation-emitting medical and dental equipment; improved state quality assurance standards for radiation-emitting equipment; federal and state exposure limits for electromagnetic radiation; an overhaul of the federal Toxic Substances Control Act to reduce unsafe chemical exposures; strengthened premarket health and safety testing and regulation of pesticides; a federal ban on the manufacture, distribution and sale of consumer products containing bisphenol A and phthalates; and strengthened oversight and regulation of the cosmetics industry. We recommend public and private investment in research on low dose exposures, mixtures, and the timing of chemical exposures, as well as the development of health tracking and biomonitoring programs designed to link data from pollution surveillance systems with disease registries.


Citations (2)


... Methotrexate (MTX) is an important anticancer, chemotherapeutic drug and immunosuppressive in organ transplantation, used in the therapy of solid tumours, leukaemia, bone cancer, severe asthma and rheumatoid arthritis [120]. Unfortunately, it is also a cytotoxic compound that acts in neoplastic cells and tissues causing serious side effects like cardiotoxicity, vomiting, diarrhoea, and hepatotoxicity, among a few [121]. ...

Reference:

Biogenic Carbon Quantum Dots: Synthesis and Applications
Policy and Research Recommendations Emerging from the Scientific Evidence Connecting Environmental Factors and Breast Cancer

International Journal of Occupational and Environmental Health

... For example, exposure to endocrine disrupting chemicals during fetal development can cause changes in the growth and development of the mammary gland which increases the chances of breast cancer in later life. Likewise, high exposures to external estrogen therapy or even the estrogenic stages of puberty may affect breast tissue and the risk of developing cancer during later stages of life [15,16]. Alongside individually focused risks, population-based studies have shown that socio-economic level, geographic area, and availability of healthcare services have considerable impact on the risk of developing breast cancer and its associated outcomes. ...

State of the Evidence: The Connection Between Breast Cancer and the Environment

International Journal of Occupational and Environmental Health