Beth McAvey’s research while affiliated with Icahn School of Medicine at Mount Sinai and other places

... The COVID-19 pandemic reshaped infertility patient experience. Evidence shows that implantation and early pregnancy rates have remained unchanged despite increased stress and anxiety [98]. Rapid diagnosis of neoplastic patients at high risk of developing sexual, psychological, and psychosocial disorders, along with prompt and personalized intervention, improves the quality of life [92]. ...

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Oncofertility and COVID-19: At the Crossroads between Two Time-Sensitive Fields

... Full efficacy and safety outcomes were presented previously. 1 Logistic regression was performed to separately identify relationships between each factor (per visit, as appropriate) and the cumulative live birth rate. Interaction effects of the factors with the treatment group (HP-hMG, rFSH) were investigated. ...

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FRESH VERSUS FROZEN EUPLOID BLASTOCYST TRANSFER OUTCOMES IN PREDICTED HIGH-RESPONDERS: MENOPUR IN GNRH (GONADOTROPIN RELEASING HORMONE) ANTAGONIST SINGLE EMBRYO TRANSFER - HIGH RESPONDER (MEGASET-HR) TRIAL ANALYSIS

... As referenced in Nazem et al., previously cryopreserved sperm samples were thawed in a 37°C incubator for 15 minutes on the morning of the scheduled dsIUI. 20 Samples were then thoroughly homogenized with a large volume pipette. The volume of the sample and spermatozoa count were recorded. ...

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Is There Clinical Value in the Mid-Luteal Progesterone Check in Same-Sex Female Couples Undergoing Donor Sperm Intrauterine Insemination?

... The first report of blastocyst rebiopsy was published in 2017 [21], and to date, most small-sample observational studies on the association between blastocyst rebiopsy and pregnancy outcomes have reported an increased risk compared to single biopsy [6,12,17,19]. In a study designed to isolate the effect of repeated TE biopsies, by controlling embryo exposure to double vitrification-warming, Sekhon and colleagues observed a 15% decrease in implantation rate in the double TE biopsy group [22]. Similarly, Zhuo and colleagues found that rebiopsied euploid embryos exhibit significantly lower odds of implantation and pregnancy compared to single-biopsied euploid embryos [16]. ...

Reference:

Double versus single blastocyst biopsy and vitrification in preimplantation genetic testing (PGT) cycles: protocol for a systematic review and meta-analysis of clinical and neonatal outcomes

... The females especially in advanced age undergoing PGS usually feel an urgency to conceive because time is not on their side and expect conception on each attempt of PGS. However, the reality is that success rate on each cycle of PGS is limited due to the high incidence of cycle cancellation [22,20] presence of high number of aneuploidy embryos and low cycle outcome [23,24]. In a multicenter randomized study, 38-41 yr. ...

Reference:

Key Factors to Avoid Cancellation of Trophectoderm Biopsy for Preimplantation Genetic Screening

... Importantly, the oldest woman included in this study was 39 years old. A separate study comparing same-sex or unpartnered women undergoing ovulation induction/IUI to heterosexual couples with any infertility diagnosis also found that both groups had similar pregnancy outcomes (Nazem et al., 2017). In this study, it was not specified whether the heterosexual couples were seeking ART due to male factor, female factor or unexplained infertility. ...

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Reproductive outcomes of women aged 40 and older undergoing IVF with donor sperm