Basil M. Kahwash’s research while affiliated with Vanderbilt University and other places

... Despite that, the evidence of HIIT protocol specifically for asthmatic population is still not conclusive. As HIIT can possibly cause distress to asthmatic patients, additional research is needed to develop a safe and effective HIIT prescription for the management of asthma (Kahwash & Nyenhuis, 2022) ...

Reference:

Exercise and Asthma: A Review

... Data from an international survey suggests that 33% of clinicians had no training on communicating exercise guidance to people with asthma, and 95% agreed that doctors require additional training in preventive care [76]. North American physicians' main barriers to physical activity counselling were limited time during consults, prioritisation of other health behaviours, and a lack of knowledge on how and where to refer patients for exercise [77]. This highlights the need for healthcare providers to be provided with the resources and education to deliver exercise and physical activity recommendations and to be aware of how to refer patients to specialists, which reinforces the importance of including this information in guidelines. ...

Reference:

Key Considerations When Addressing Physical Inactivity and Sedentary Behaviour in People with Asthma

... 31,32 When allergic contact dermatitis to a suture is suspected, placing a patch test with the suture material on the epidermis has low sensitivity. The interrupted dermal stitch test is a recognized technique to aid in the diagnosis of suspected ACD to a suture material [50][51][52] , although further patch testing may be necessary to identify the specific culprit ingredient in the suture. Our case follows this pattern. ...

Reference:

Triclosan Allergy Mimicking Recurrent CIED Infections

... Moreover, some eosinophilic disorders like the so-called "overlap HESs" (e.g., single-organ eosinophil-associated diseases, eosinophilic granulomatosis with polyangiitis (EGPA) or IgG4-related disease (IgG4RD)) were also systematically excluded from these studies. To date, no multicenter prospective study has been conducted in the field of HE/HES and there is an urgent need for the prospective collection of real-life data [16][17][18]. This is especially critical as new biologic therapies are now available (or will likely be available soon) e.g., conventional, or long-acting anti-interleukin-5 (IL-5), anti-IL-5Rα, anti-Siglec-8, or Janus kinase inhibitors (JAKi), for which good use depends on good characterization of the HES [19]. ...

Reference:

Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort

... [20] Downloaded from http://journals.lww.com/md-journal by BhDMf5ePHKav1zEoum1tQfN4a+kJLhEZgbsIHo4XMi0hCy wCX1AWnYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC4/OAVpDDa8K2+Ya6H515kE= on 11/30/2024 A qualified exercise physiologist guided the program, ensuring adherence to recommended exercise prescription guidelines. [28] The training was conducted on a motor-driven, indoor treadmill (HP Cosmos Mercury® Med, Nussdoerf-Traunstien, Germany) and was adapted to accommodate each child's capacity. Initially (i.e., over the first 2 weeks), the training lasted 25 minutes, with a walking pace set at 50% of their HR max . ...

Reference:

Exercise strategies for reversing cardiopulmonary deconditioning in obese children with bronchial asthma: A randomized comparative effectiveness study of constant-load and graded aerobic training

... These results rather argue against IgE-mediated allergy in most of these patients, even though an alternative hypothesis is that the amount of PEG in mRNA vaccines is much lower than in other preparations and might not reach the reaction threshold. Likewise, there are studies with patients who had a reaction to substitution therapy with PEG-asparaginase (containing PEG 5000), but had no reaction to mRNA vaccination, and some of them had previously tolerated PEG-containing laxatives [38]. ...

Reference:

SARS-CoV-2 and allergy – what have we learned after two and a half years?

... Eosinophilic esophagitis (EoE) is a chronic type 2 inflammatory disease restricted to the esophagus, 1 and consisting in an immunemediated reaction to antigens in the esophageal lumen, predominantly from the diet. 2 EoE commonly associates with other type 2 atopies, and has been proposed as a late manifestation of the allergic march. 3 From first description of the disease, a 3-to-4 times higher prevalence of EoE has been reported in males of all ages, compared to females. 4 Suggested explanations for this range from genetic causes, 5 sex-related differences in gene expression profiles 6 and molecular signatures, 7 to anatomical and functional differences in the esophagus, 8 gender-associated differences in lifestyle and exposure to environmental factors. 9 Excepting EoE, a pronounced female predominance has been described in most immune-mediated diseases, 10 and sex-related variations in the natural course, risk for progression and response to treatment has been demonstrated. ...

Reference:

Sex‐related differences in the presentation, management and response to treatment of eosinophilic esophagitis: Cross sectional analysis of EoE CONNECT registry

... The successful introduction of newborn screening (NBS) for phenylketonuria in dried blood spots (DBSs) by the pioneering work of Dr. Robert Guthrie in the early 1960s has been the catalyst for establishing population-based newborn screening in the United States for over 30 disorders to date [1]. There has been increasing global interest in expanding newborn screening panels to include more genetic diseases due to significant advances in screening for early-onset ADA deficiency [33], a small percentage of patients who develop symptoms later in life can be missed by this NBS method [34,35]. Enzyme replacement therapy, gene therapy or HSCT are the available treatment options [36,37]. ...

Reference:

Advancing Newborn Screening in Washington State: A Novel Multiplexed LC-MS/MS Proteomic Assay for Wilson Disease and Inborn Errors of Immunity

... A 2019 national survey of U.S. and Canadian allergy/immunology and pulmonology physicians revealed that, whereas 92% believe exercise should be a component of asthma management, only 69% regularly perform exercise counseling. 87 One respondent commented that, whereas exercise is "probably the most important [recommendation]" for asthma patients, lack of time presents a barrier to counseling. A lack of confidence in discussing exercise with patients was also noted among survey respondents: 26% described having no knowledge or very little knowledge on exercise counseling, whereas only 9% felt that they were very knowledgeable about encouraging patients to exercise. ...

Reference:

Physical Activity and Asthma: The evidence for it and how to get my patients to do it: A Work Group Report of the AAAAI Sports, Exercise, and Fitness Committee

... Esta encuesta está constituida por 11 preguntas de selección múltiple o valoración. Para este trabajo, se utilizaron diversos estudios realizados a estudiantes de postgrado de medicina como fuente referencial en el tipo de preguntas realizadas 15,16 . Todos los participantes debían confirmar su participación mediante la aceptación de consentimiento informado online. ...

Reference:

Chilean Otorhinolaryngology residents’ perception regarding the adaptation of their respective teaching programs during Covid-19 pandemic