Baru Chandrasekhara Rao's scientific contributions

Publication (1)

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Purpose: To prepare and characterize tablets loaded with self-nanoemulsifying drug delivery system (SNEDDS) containing docetaxel (DTL). Method: SNEDDS of docetaxel were prepared using various oils, surfactants, co-surfactant and solvents to improve the dissolution rate and bioavailability of the poorly water-soluble chemotherapeutic agent. The SNED...


... 21 The simplest way is the physical adsorption onto solid carriers as it involves the adsorption of liquid SNEDDS onto solid carriers by physical mixing to form free-flowing powders which can be filled into hard gelatin capsule or compressed into tablets after the addition of suitable excipients. 12,15,22 In recent years, porous carriers with large surface area as Aerosil ® 200 Pharma and Aeroperl ® 300 Pharma are used as solid carriers for the solidification of SNEDDS. 23 Aerosil ® 200 Pharma is a high-purity amorphous anhydrous colloidal silicon dioxide with average particle size of 12 nm (primary particles) and a specific surface area of 200 m 2 /g. ...