Babak Shekarchi's research while affiliated with AJA University of Medical Sciences and other places

Publications (63)

Article
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: The present study aimed to estimate the age, gender, and height of the Iranian population based on the characteristics of the 10th and 11th thoracic vertebrae for identification. This cross-sectional study measured the T10 and T11 indices in axial, sagittal, and coronal computed tomography (CT) scan images. The measured indices included vertebral...
Article
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Purpose Studies have suggested some predictors for hamstring tendon (HT) autograft diameter based on anthropometric factors and preoperative magnetic resonance imaging (MRI) with variable results. Some authors have attributed the variability to gender differences. This prospective cohort reports the sensitivity and specificity of anthropometric and...
Article
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Background Multiple sclerosis (MS) is recognized as the most prevalent autoimmune abnormality of the CNS. T1WI, T2WI, and FLAIR are limited in the quantification of tissue damage and detection of tissue alterations in white and grey matter in MS. This study aimed to the evaluation of changes in DTI indices in these patients at the thalamus and basa...
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In this study, we aimed to assess the association between different parameters of the second and third lumbar vertebra with age, sex, and height in the Iranian population. A total of 14 parameters of the L2 and L3 vertebra were measured from three-dimensional lumbar topography. The measured parameters included vertebral length, foramen diameter, fo...
Article
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Background There are several therapeutic options for hepatocellular carcinoma (HCC). As predicting the treatment response is critical in clinical decision making, we aimed to evaluate the quantitative intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters as potential predictors of treatment response of HCC lesions to trans...
Article
Objective: We aimed to investigate the extent of pulmonary involvement and adverse outcomes in patients receiving angiotensin-converting enzyme inhibitor (ACEI)/ angiotensin II receptor blocker (ARB) versus who did not, in hospitalized coronavirus infectious disease 2019 (COVID-19) patients. Methods: All COVID-19 patients with a positive polymerase...
Article
Background There is controversy regarding Alberta Stroke Program Early CT Score (ASPECTS) and platelet indices as predictors of outcome in patients with acute ischemic stroke (AIS). We aimed to assess the prognostic value of ASPECTS, mean platelet volume (MPV), plateletcrit (PCT), and platelet count (Plt) in 3-month and 1-year functional outcomes o...
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Background: Different parts of the skeletal system have been studied in different studies to determine gender. The pelvis is one of the most important skeletal components for the determination of gender and identification of humans. Objectives: The current study aimed to determine gender using the ischiopubic index and upper pelvic index in the adu...
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Introduction: In this study, we intend to determine the correlation between the thickness of the cerebral cortex and the severity of the cognitive disorder in Alzheimer disease (AD). Methods: A total of 20 (14 women and 6 men) patients diagnosed with AD with a Mean age of 72.95 years, and 10 (7 women and 3 men) cognitively normal (CN) subjects w...
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Background: One of the treatment modalities for thyroid cancer and hyperthyroidism is radioiodine-131 (I-131) therapy. The use of this therapeutic modality is not completely safe and can lead to oxidative stress, eventually DNA damages. However, these radiation-induced damages can be reduced by antioxidants. This study aimed to investigate the pot...
Article
Thalamus plays an important role in the pathogenesis of multiple sclerosis-related fatigue (MSrF). However, the thalamus is a heterogeneous structure and the specific thalamic subregions that are involved in this condition are unclear. Here, we used thalamic shape analysis for the detailed localization of thalamic abnormalities in MSrF. Using the M...
Article
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Background and objectives: Recent studies have hypothesized that sterile disc infection with the anaerobic Propionibacterium acnes, recently renamed Cutibacterium acnes, occurs in people with intervertebral disc (IVD) herniation. This study aimed to examine the presence of P. acnes in patients who have Low back pain (LBP) with Modic changes observ...
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Background: Thyroid cartilage ossifies through time. In addition to different methods for age estimation, ossified volume can be a valuable index for age estimation. In this study, anthropometric characteristics and ossified volume were measured using CT scan imaging to find potential correlations between measures and age. Methods: In this study, 1...
Article
Background: The earlier studies did not assess the associated factors of anterolateral ligament injury, comprehensively. We sought to evaluate the independent predictive factors of anterolateral ligament injury in the patients with anterior cruciate ligament tear. Ultrasound scan has an emerging role in the diagnosis of anterolateral ligament inju...
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In this study, large-area (6-cm diameter) Teflon polytetrafluoroethylene (PTFE) discs of different thicknesses (0.2-, 0.5- and 1 -mm) were negatively and positively charged by using the “modified single point-to-plane corona poling rotating system”. The effects of some crucial parameters of the PTFE disc as well as the modified corona poling rotati...
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Background: Although radiotherapy is a common choice for cancer therapy, various types of toxicities in irradiated normal tissueslimit the received dose by tumor cells. The gastrointestinal tract is one of the most sensitive organs to the detrimental effects of radiation. As a result of a high dose of ionizing radiation, acute morphological changes...
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Aims: The current study aimed to investigate the potential role of melatonin for mitigation of radiation-induced gastrointestinal injury. Background: Organs of the gastrointestinal system such as the intestines, colon, duodenum, ileum etc. are sensitive to ionizing radiation. Mitigation of radiation-induced gastrointestinal injury is an interestin...
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Introduction: Head trauma is a common reason for emergency department visits worldwide; many of which involve young children. We sought to determine if head ultrasound (US), as a portable, fast and safe modality, can guide diagnosis and treatment of children in emergency settings. Methods: In this cross-sectional study, brain computed tomography (C...
Article
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Introduction: Head trauma is a common reason for emergency department visits worldwide; many of which involve young children. We sought to determine if head ultrasound (US), as a portable, fast and safe modality, can guide diagnosis and treatment of children in emergency settings. Methods: In this cross-sectional study, brain computed tomography...
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Objective: To evaluate the accuracy of internal jugular vein waveform to detect early stage of hemorrhagic shock. Methods: Forty-three volunteers enrolled in our study between November and December 2018. After blood donation of 450cc, the blood donors in the case group underwent color Doppler sonography of internal Jugular Vein. Besides, the cli...
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We compared the efficacy and safety of a biosimilar form of beta-interferon-1a (Actovex) versus the reference product in the treatment of relapsing remitting multiple sclerosis (RRMS). In a double blind, randomized phase 3 clinical trial, we evaluated 138 patients with RRMS that were allocated to receive the biosimilar medication and the reference...
Article
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BACKGROUND: During the eight years of the imposed war, Iraq used various chemical agents such as sulfur mustard and nerve agents (mainly tabun and sometimes soman) on Iran's soldiers. Using information obtained from specialist sequences and analysing information obtained from magnetic resonance imaging (MRI) in a susceptibility weighted imaging (SW...
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Background: The search for potent radioprotective agents for the amelioration of radiation side effect is an important aim in radiobiology. The present study aimed to evaluate the effects of curcumin and seleno-L-methionine against radiation-induced micronucleus formation in rat bone marrow. Methods: In total, 40 male rats were divided into 8 gr...
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Background: This study aims to investigate the ability of BSMI, to preoperative evaluation of tumor adhesion to adjacent brain tissue in patients with meningioma and comparing this method to the width of edema around tumor, using surgery findings as the reference standard. Methods: Thirty patients with meningioma brain tumor who underwent surgery a...
Article
Large bone defects constitute a major challenge in bone tissue engineering and usually fail to heal due to the incomplete differentiation of recruited mesenchymal stem cells (MSCs) into osteogenic precursor cells. As previously proposed, metformin (MET) induces differentiation of MSCs into osteoblastic lineages in vitro. We fabricated a Poly (lacti...
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Introduction Timely diagnosis and treatment of traumatic injury to ulnar collateral ligament (UCL) of thumb is of special importance for preserving the full function of the hand. Therefore, the present study has been designed with the aim of evaluating the accuracy of ultrasonography in detection of these injuries. Methods The present diagnostic a...
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Introduction Using bedside ultrasound in diagnosing acute cholecystitis in the emergency department (ED) can save time, help the decision making process and allocate resources wisely. This study aimed to evaluate the diagnostic accuracy of bedside right upper quadrant (RUQ) ultrasonography in detection of acute cholecystitis. Method In this diagno...
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Introduction: This study aimed to calculate the photon and neutron doses received to the contralateral breast (CB) during breast cancer radiotherapy for various field sizes in the presence of a physical wedge. Materials and methods: Varian 2100 C/D linear accelerator was simulated using a MCNP4C Monte Carlo code. Then, a phantom of real female c...
Article
Free radicals and reactive oxygen species (ROS) are generated using various endogenous systems or from external sources such as exposure to different physiochemicals. Ionizing radiation damage to the cell can be caused by the direct or indirect effects of radiotherapy processes. Silymarin (SM), a flavanolignan compound, has been identified as a nat...
Article
Introduction: Idiopathic generalized epilepsy (IGE) is a kind of epilepsy that has tonic-colonic characteristic and myocolonic tensions and its clinical symptom starts from the first 20 years of the life. Proton magnetic resonance spectroscopy (H1-MRS) technique applies as a noninvasive procedure to find metabolic disorders by evaluating brain meta...
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Several strategies have been used to promote bone repair; with many failing due to the lack of osteoinduction. We describe our approach for promoting bone healing that attempts to overcome prior shortcomings. First, we compared the role of different concentrations of Gelatin (Gel), nanostructured-hydroxyapatite (nHA), Simvastatin (Sim) and nHA-Sim...
Article
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This research aimed to measure the received photon and thermal neutron doses to contralateral breast (CB) in breast cancer radiotherapy for various field sizes in presence of physical and dynamic wedges. The measurement of photon and thermal neutron doses was carried out on right breast region of RANDO phantom (as CB) for 18 MV photon beams. The do...
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Small fields are more repeatedly used for radiation therapy as small segments in intensity-modulated radiotherapy or as in the form of independent fields in stereotactic radiosurgery and other novel equipment such as cyberknife and tomotherapy. Nevertheless, the application of small fields for radiotherapy of lung makes the dose calculation and pla...
Article
Background Chronic exposure to noise is known to cause a wide range of health problems including extracellular matrix (ECM) proliferation and involvement of cardiovascular system. There are a few studies to investigate noise-induced vascular changes using noninvasive methods. In this study we used carotid artery intima-media thickness (CIMT) and ao...
Article
Background: Chronic exposure to noise is known to cause a wide range of health problems including extracellular matrix (ECM) proliferation and involvement of cardiovascular system. There are a few studies to investigate noise-induced vascular changes using noninvasive methods. In this study we used carotid artery intima-media thickness (CIMT) and a...
Article
Purpose Tibial tuberosity–trochlear groove (TTTG) distance is currently considered as one of the main factors in decision-making for surgical intervention in patients with patellar instability. The current study aimed to provide a valid comparison of TTTG distance in the healthy knees with those with patellar instability. Materials and methods Pati...
Conference Paper
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سابقه و هدف: نقیصه های بزرگ استخوانی به دلایل مختلفی ایجاد می شوند. ترمیم نقیصه های استخوان های دراز روندی مشکل است. اتوگرافت ها و آلوگرافت ها از جمله انتخاب های موجود برای بازسازی نقیصه های استخوان های دراز می باشد. با این حال استفاده از این انتخاب ها دارای محدودیت های جدی در نقیصه های بزرگ است. مهندسی بافت انتخاب های جدیدی را ارائه کرده است با ای...
Article
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Electrocardiogram (ECG) signals might be affected by various artifacts and noises that have biological and external sources. Baseline wander (BW) is a low-frequency artifact that may be caused by breathing, body movements and loose sensor contact. In this paper, a novel method based on empirical mode decomposition (EMD) for removal of baseline nois...
Article
Aims: Previous reports on the possible effects of Extremely Low Frequency Magnetic Fields (ELF MF) on mood have been paradoxical in different settings while no study has yet been conducted on animal behavior. In addition, it was shown that ELF MF exposure makes an increase in brain nitric oxide level. Therefore, in the current study, we aimed to a...
Article
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Communicated by Cecilia Pennetta Electrocardiogram (ECG) signals might be affected by various artifacts and noises that have biological and external sources. Baseline wander (BW) is a low-frequency artifact that may be caused by breathing, body movements and loose sensor contact. In this paper, a novel method based on empirical mode decomposition (...
Article
Oscillations of electroencephalographic signals represent the cognitive processes arose from the behavioral task and sensory representations across the mental state activity. Previous studies have shown the relation between event-related EEG and sensory-cognitive representation and revealed that categorization of presented object can be successfull...
Article
The purpose of this study was to investigate the diagnostic accuracy of a dual-source CT (DSCT) coronary angiography in parallel with a CT angiography. On the other hand, we compared the DSCT angiography of the internal carotid artery plaque with the histopathological specimens. Ninety patients underwent DSCT and an invasive coronary angiography (I...
Article
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Purpose: To report three cases of optic nerve aplasia (ONA). Case report: Herein three subjects with ONA are described, two subjects had unilateral involvement. In one of these cases, the fellow eye had an associated persistent hyperplastic primary vitreous (PHPV). The third patient had bilateral ONA with multiple intracranial anomalies. Previou...
Article
Treatment of large bone defects (LBDs) is technically demanding. Tissue engineering is an option. A bioactive graft may be produced by combining tissue scaffolds and healing promotive factors in order to accelerate bone repair. We investigated the role of Simvastatin (Sim)-embedded porous Gelapin (Gel) scaffold on experimental bone healing. At firs...
Conference Paper
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Background and Objective Large bone defects could be happened due to surgical resection of diseased bone or after internal fixation of complicated fractures. Autogenous cancellous bone grafts are gold standard method for filling the defect. Allograft bony tissue is an option with lower osteogenic and osteoinductive properties than autografts. Both...
Article
Relapsing-remitting multiple sclerosis (RRMS) is a chronic inflammatory demyelinating disease of the central nervous system. Magnetic Resonance Imaging (MRI) has a remarkable role in the assessment of the disease. The aim of the study is to evaluate MRI features and also to determine linear correlation between them. Nineteen RRMS patients (5 males,...
Article
Skeletal-muscle problems are considered as a major cause of disability in developed countries. The articular surface Damages and in the higher levels of disease, subchondral bone injuries, indicate degenerative joint disease progression. Military forces, as a non-communicable disease imposing an extra burden on the health system of armed forces, is...
Article
Attention Deficit Hyperactivity Disorder (ADHD) affects nearly 5% of school-aged children and generally it continues to adulthood. Neural basis of ADHD has been a matter of debate in recent decades. In this study a group independent component analysis based study has been done on 21 ADHD individuals and 21 control group. Spatial maps have been deri...
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In stable patients with blunt abdominal trauma, accurate diagnosis of visceral injuries is crucial. To determine whether repeating ultrasound exam will increase the sensitivity of focused abdominal sonography for trauma (FAST) through revealing additional free intraperitoneal fluid in patients with blunt abdominal trauma. We performed a prospective...
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Background: Delayed pneumothorax and hemothorax are among the possible fatal complications of blunt thoracic trauma. Objectives: Finding reliable criteria for timely diagnosis of high-risk patients has been an area of interest for researchers. Material sand Methods: We gathered a database including 616 patients among which, 17 patients experienced...
Article
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Background: As both oral and verbal apraxia are related to vocal orofacial musculature, this study aimed at identifying brain regions impaired in cases with oral and verbal apraxia. Methods: In this non-experimental study, 46 left brain damaged subjects (17 females) aged 23–84 years, were examined by oral and verbal apraxia tasks. Impaired and spa...
Poster
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Assessment of ureterovesical jet dynamics in obstructed ureter by urinary stone with color Doppler and duplex Doppler examinations
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Increased intra-abdominal pressure (IAP) results in dysfunction of vital organs. The aim of the present study was to evaluate the effect of mechanical ventilation mode on IAP. In a cohort study, a total of 60 patients aged 20-70 years who were admitted to the ICU and underwent mechanical ventilation were recruited. Mechanical ventilation included o...
Article
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This study was designed to evaluate ureterovesical jet dynamics in obstructed ureter and to compare it with those of contralateral unobstructed side. Forty-six patients with diagnosis of ureteral stone, based on imaging findings in computed tomography were enrolled in this study. The gray-scale ultrasound exam from both kidneys and urinary bladder...
Article
Addiction to opium continues to be a major worldwide medical and social problem. The study addressing the association between opium consumption and serum prostate-specific antigen (PSA) level is lacking. We determined the effects of opium consumption on serum PSA levels in opium-addict men. Our study subjects comprised 438 opium-addict men with a m...
Article
Parkinson's disease (PD) is one of the most commonly occurring neurodegenerative disorders, with lifetime incidence between 1 and 2% among people older than 65 years. ED is one of the more disabling and poorly addressed aspects of PD. The purpose of this study was to assess the efficacy and safety of sildenafil citrate in Parkinson-emergent ED. Sex...
Article
• To investigate the association of the T-786C, G894T and variable number of tandem repeats (VNTRs) in intron 4 (a/b) polymorphisms of the eNOS gene in Iranian subjects with vasculogenic erectile dysfunction (ED). • A total of 322 consecutive patients with vasculogenic ED were recruited. Patients with concomitant risk factors for ED were excluded....
Article
Full-text available
Parkinson's disease (PD) is one of the most commonly occurring neurodegenerative disorders, with lifetime incidence between 1 and 2% among people older than 65 years. ED is one of the more disabling and poorly addressed aspects of PD. The purpose of this study was to assess the efficacy and safety of sildenafil citrate in Parkinson-emergent ED. Sex...

Citations

... If human bones are involved, further examination procedures follow, regarding the postmortem interval (PMI) [5][6][7][8][9][10], pre-or peri-mortem traces of injury or postmortem defects [11][12][13] and findings indicating or assuring identity [14][15][16][17][18][19][20][21]. The results of the examination should be interpreted and presented in a written report to support the authorities in their further investigations [3,22]. ...
... and death (OR: 0.23; 95% CI: 0.14-0.38), compared to those receiving no treatment [161]. In another study, COVID-19 patients receiving RAS inhibitors (hazard regression (HR) = 0.499, 95% CI: 0.325-0.767) ...
... It is well-known that platelets are activated in various infectious and non-infectious pathological conditions, such as acute myocardial infarction (35), cerebrovascular disease (36), and diabetes mellitus (37). Similar to the aberrant neutrophil behaviour observed in sepsis, platelet activation plays a significant role in these conditions. ...
... The pipeline of GM measurement was summarized as follows: (1) nonuniform field correction; (2) removal of the skull and other nonbrain tissues; (3) registration with brain atlas; (4) intensity normalization; (5) WM segmentation; (6) filling of brain surface; (7) reconstruction of whole brain; and (8) measurement of cortical characteristics of brain regions. [14][15][16] Especially, intensity inhomogeneity in brain MR images increases the difficulties in tissue segmentation. Therefore, several approaches have been proposed in the literature such as a proposed automatic normalization method using statistical features. ...
... Parotid massages, aromatherapy, vitamin E, selenium, and bethanechol showed a significant reduction in the salivary gland dysfunction induced from the 131 I treatment (2960-7890 MBq) [43]. Additionally, keratinocyte growth factor-1 (KGF-1) (100 µg/1 mL PBS) restored saliva homeostasis and reduced the 131 I-induced (0.01 mCi/g) cell apoptosis in the mice [90]. A marker of lipid peroxidation, 8-Epi-PGF 2α, is the outcome of free radical-mediated arachidonic acid peroxidation, and the effect of high-activity treatment (2960 or 7400 MBq) is significantly higher and longer in length than that of low-activity treatment (185 or 740 MBq), with a dose-dependent oxidative damage in vivo [107]. ...
... Four studies linked fatigue in pwRRMS to thalamic atrophy (102,105,123,134) and one to lesion load in the thalamus (113). Moreover, three studies associated fatigue with cerebellar atrophy (105,131,134) and three with basal ganglia structures (100,102,105). ...
... Albert et al. reported 46% of positive cultures for anaerobes in 61 patients undergoing lumbar discectomy, of which 80% had Modic type 1 changes [15]. Other studies corroborate these findings, with high identification rates for Cutibacterium acnes, an anaerobic and aerotolerant pathogen that is bacillus-shaped, stained by the Gram method, pleomorphic, non-spore-forming, and a biofilm producer [11,[16][17][18][19][20]. Rollason et al. isolated strains of this bacterium from the LIVD of 64 patients, revealing the presence of genotypic profiles distinct from those found in the skin, suggesting that specific variants would be related to LBP [21]. ...
... The injury to the ALL was also associated with a positive pivot shift test. In 2020, (Shekari et al., 2020) enrolled 198 patients with ACL tears, all of whom had ALLs visible under US imaging. A total of 110 patients (55.6%) were found to have impaired ALLs. ...
... Возможности УС при переломах костей свода черепа. Высокая диагностическая точность УС в диагностике переломов костей свода черепа у детей подтверждена многими исследованиями [9][10][11][12][13][14][15][16][17][18][19][20][21]. В 2022 г. ...
... Irradiation caused inflammation and severe damage in both the duodenum and jejunum. However, pre-treatment with metformin showed a remarkable amelioration of these damages, especially for villi shortening and epithelial injury [85]. Further experiments need to dissect the possible protective effects of metformin against the gastrointestinal side effects of chemotherapy drugs. ...