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... Apart from the instability of γ' precipitates occurring during ion or fast neutron irradiation, some other factors which should be taken into consideration while servicing in a reactor environment such as the helium effects, have not been investigated. In nuclear materials containing Ni, large amount of helium might be produced through the (n, α) transmutation via absorption of neutrons at thermal energies [23,24]. Taking Inconel X-750 components in cores of Canada Deuterium and Uranium (CANDU) reactors as an illustration, the production rate of helium by Ni transmutation reaches as high as 3×10 −4 atoms helium per dpa [9,24]. ...