Azharul Islam Khan's research while affiliated with International Centre for Diarrhoeal Disease Research, Bangladesh and other places

Publications (9)

Article
Full-text available
Background: This study describes phenotypic, genotypic and antibiotic susceptibility patterns of the strains isolated from the 2012 Sierra Leone cholera outbreak. Rectal swabs were collected from patients and cultured for Vibrio cholerae O1. Methods: The isolates were subjected to multiplex PCR, mismatch amplification mutation assay (MAMA) PCR,...
Article
Full-text available
During August 2008-June 2009, an estimated 95,531 suspected cases of cholera and 4,282 deaths due to cholera were reported during the 2008 cholera outbreak in Zimbabwe. Despite the efforts by local and international organizations supported by the Zimbabwean Ministry of Health and Child Welfare in the establishment of cholera treatment centres throu...
Article
The present study investigated prospectively programmatic factors relating to dropouts in child vaccination in 6 subdistricts of Bangladesh. A cross-sectional survey (n = 2700) was conducted estimating overall coverage of immunization using cluster sampling. The eligible subsample of children (n = 1064) was followed up prospectively to understand r...
Article
Full-text available
This paper details the phenotypic, genotypic, and antibiotic sensitivity patterns of 88 Vibrio cholerae strains from Zimbabwe. Of the 88 strains, 83 were classified as “altered El Tor” and 5 as “hybrid El Tor” strains. All of the strains were susceptible to tetracycline, doxycycline, ciprofloxacin, and azithromycin by disc diffusion, but susceptibi...
Article
The cholera epidemics of the 19th century forged the way for the sanitation revolution and the provision of safe public water sources that are the hallmark of developed countries. Nevertheless, more than 1 billion people today, including much of the population in Haiti, lack access to improved water supply sources and hence remain vulnerable to epi...
Conference Paper
Background: Contaminated water used to clean bottles or mix artificial milk can lead to transmission of infectious organisms. Though the WHO recommends exclusive breastfeeding (EBF) for all children under 6 months of age, bottle-feeding has increased in Bangladesh in recent years. At ICDDR,B, mothers of children admitted for diarrheal illness atten...
Article
Full-text available
This article assessed the status of childhood vaccination coverage and the possibility of using selected alternative vaccination strategies in rural hard-to-reach haor (low lying) areas of Bangladesh. Data were collected through survey, in-depth interviews, group discussion, and observations of vaccination sessions. Complete immunization coverage a...
Conference Paper
This work examines the International Center for Diarrheal Diseases Research, Bangladesh's (ICDDR,B) successful response to an extreme outbreak of diarrheal diseases in July- September 2007 following an intense monsoon season. We compared ICDDR,B's policies and practices during the recent outbreak with those of other facilities during a 1994 diarrhe...
Article
Full-text available
Zinc is an essential micronutrient associated with over 300 biological functions. Marginal zinc deficiency states are common among children living in poverty and exposed to diets either low in zinc or high in phytates that compromise zinc uptake. These children are at increased risk of morbidity due to infectious diseases, including diarrhoea and r...

Citations

... A study on the 1965-2006 seventh pandemic El Tor strains from China revealed new ctxB genotypes as () with the presence of tcpA El , rstR Cl , rstR El+Cl , rstR El , rstR232 and rtxC (Zhang et al., 2013). Other studies on 1996-2012 Chinese cholera outbreak (Ansaruzzaman et al., 2007;Ansaruzzaman et al., 2004;Ceccarelli et al., 2011;Hounmanou et al., 2019a;Hounmanou et al., 2019b;Kachwamba et al., 2017;Mahmud et al., 2014;Marin et al., 2013;Mercy et al., 2014;Quilici et al., 2010;Weill et al., 2017;Ngwa et al., n.d.;Lee et al., 2006;Abana et al., 2019;Irenge et al., 2020;Saidi et al., 2014) , ICEVchBan5, ICEVchBan9, VC1786ICE Bhuyan et al., 2016;Das et al., 2016;Ghosh et al., 2017;Ghosh et al., 2014a;Ghosh et al., 2014b;Ghosh-Banerjee et al., 2010;Goel et al., 2008;Jain et al., 2013;Koley et al., 2014;Kumar et al., 2018;Kumar et al., 2014a;Kumar et al., 2014b;Kumar et al., 2020;Naha et al., 2012;Pal et al., 2017;Pal et al., 2013;Samanta et al., 2018;Taneja et al., 2009;Bhattacharya et al., 2016;Kumar et al., 2016;Kutar et al., 2013 isolates revealed the presence of seventh pandemic Atypical El Tor variants with genotypes, antimicrobial resistance profile and the presence of SXT element as shown in Table 2. ...
... health workers are available and provide with adequate medical resources [3]. Unfortunately, mortality rates remain way too high in several areas of the developing countries including Zimbabwe that recorded 4.3% case fatality rate during the 2008-2009cholera outbreak [4]. ...
... An outbreak in Haiti following the 2010 earthquake infected nearly 700,000 people and has caused over 8,500 deaths (4). In a 2008 epidemic in Zimbabwe, more than 90,000 suspected cholera cases were reported, with more than 4,000 patient deaths (5). ...
... While improvements to water, sanitation, and hygiene (WASH) have eliminated cholera in Europe and North America, the disease remains endemic in at least 47 countries [48], resulting in an estimated 1.3 to 4.0 million cases and 21,000 to 143,000 deaths annually worldwide [47]. Large outbreaks of cholera have been documented following natural disasters or in war zones, as documented in Haiti [16] or Yemen [7], and multiple countries in Africa have seen a growing number of outbreaks in the past few years [32]. Current interventions to control and prevent cholera include cholera vaccines, administration 1 of oral rehydration solutions, investments in WASH, and improvement of health systems [48]. ...
... Additional sites are mostly for delivery of primary health care services either known as satellite clinics or static health facilities. In rural areas, EPI services are delivered once a month and vaccines are administered free of charge in these places [10][11][12][13][14]. Although the success of EPI is well-acclaimed approximately 1.5 million children die each year because of vaccine-preventable diseases [15]. ...
... Several research have been carried out in Haor area, studying the impact of flash floods on crop production (Ahmed et al., 2017;Khan et al., 2012;Shaw, 2018), assessing quality of peoples knowledge for climate change adaptation and livelihood exposure to climate change (Haque et al., 2017;Rahman et al., 2018), determining the child immunization coverage and maternal health care seeking behavior (Haque et al., 2016;Uddin et al., 2009) and so on in the past, but no study has explored how flash floods may affect the food security of the flood-affected people of this region. Therefore, there is a lack of evidences on this issue, which is of utmost importance for developing programs and policies to combat food insecurity effectively at emergency situations like post flash flood scenario. ...
... A 1-year observational study of 20,246 children (aged 3-59 months) with diarrhea observed that regurgitation and/or vomiting occurred in 4392 (21.8%) cases. However, this phenomenon was transient and did not affect the continuation of zinc treatment [33]. According to meta-analyses of randomized, controlled intervention trials on children, the World Health Organization (WHO) and United Nations Children's Fund (UNICEF) advocate for the regular use of zinc in treating children under the age of five with acute diarrhea, irrespective of its cause. ...