Asgar Ali Kalla's research while affiliated with University of KwaZulu-Natal and other places
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Publications (22)
Background
Gender disparities in health care are pervasive worldwide, including the field of rheumatology in Africa, where there is a scarcity of rheumatologists. The heterogeneity of these disparities underscores the importance of addressing unmet needs at a regional level. We aimed to determine the number of rheumatologists in Africa, the gender...
Musculoskeletal (MSK) health impairments contribute substantially to the pain and disability burden in low- and middle-income countries (LMICs), yet health systems strengthening (HSS) responses are nascent. We aimed to explore the contemporary context, framed as challenges and opportunities, for improving population-level prevention and management...
Background
Glucocorticoid (GC) use is well established in the treatment of rheumatics diseases, particularly rheumatoid arthritis (RA). The use of low dose GC has been endorsed by EULAR recommendations for the management of rheumatic and musculoskeletal diseases even if in the context of SARS-CoV-2, but long-term use is generally discouraged.
Obje...
The hip fracture rates in South Africa were used to create ethnic-specific FRAX® models to facilitate fracture risk assessment.
Introduction
The aim of this study was to develop FRAX models to compute the 10-year probability of hip fracture and major osteoporotic fracture and assess their potential clinical application.
Methods
Age- and sex-speci...
The objective of this consensus statement is to inform the clinical practice communities, research centres and policymakers across Africa of the results of the recommendations for osteoporosis prevention, diagnosis and management. The developed guideline provides state-of-the-art information and presents the conclusions and recommendations of the c...
Introduction
Despite the profound burden of disease, a strategic global response to optimise musculoskeletal (MSK) health and guide national-level health systems strengthening priorities remains absent. Auspiced by the Global Alliance for Musculoskeletal Health (G-MUSC), we aimed to empirically derive requisite priorities and components of a strate...
Spondyloarthritis (SpA) has been less well studied than rheumatoid arthritis in North Africa, due to a belief that it is rare and benign in certain populations. The main genetic trait of SpA is its association with human leukocyte antigen (HLA)-B27. The distribution of this allele largely explains the prevalence and severity of SpA. The prevalence...
Objectives. To identify the changes in rheumatology service delivery across the five regions of Africa from the impact of the COVID-19 pandemic. Methods. The COVID-19 African Rheumatology Study Group created an online survey consisting of 40 questions relating to the current practices and experiences of rheumatologists across Africa. The CHERRIES c...
Objectives:
To identify the changes in rheumatology service delivery across the five regions of Africa from the impact of the COVID-19 pandemic.
Methods:
The COVID-19 African Rheumatology Study Group created an online survey consisting of 40 questions relating to the current practices and experiences of rheumatologists across Africa. The CHERRIE...
The rise in non-communicable diseases in Africa presents challenges for health systems that are burdened by infectious diseases. Gout is one of those diseases that has seen an increase in numbers worldwide, including Africa. Gout is commonly associated with comorbidities and mortality. It directly impacts the quality of life, increases health costs...
Objectives:
To develop recommendations for the management of rheumatic and musculoskeletal diseases (RMDs) during the COVID-19 pandemic.
Method:
A task force comprising of 25 rheumatologists from the 5 regions of the continent was formed and operated through a hub-and-spoke model with a central working committee (CWC) and 4 subgroups. The subgro...
Africa is experiencing an exponential increase in the number of older persons. The number of persons surviving with human immunodeficiency virus is simultaneously increasing due to improved availability of anti-retroviral therapy. The burden of non-communicable diseases, in particular, osteoporosis and its consequent fragility fractures, is also pr...
Abstract
Objectives. To identify the changes in rheumatology service delivery across the five regions of Africa from the
impact of the COVID-19 pandemic.
Methods. The COVID-19 African Rheumatology Study Group created an online survey consisting of 40 questions
relating to the current practices and experiences of rheumatologists across Africa. The C...
Citations
... Sustained advocacy and calls for action have been made for greater prioritisation of musculoskeletal health within health reform agendas, ignited by the 2000-2010 Bone and Joint Decade [10]. While there is undoubtedly greater awareness of the health, social and economic burden attributed to impaired musculoskeletal health (conditions, primary pain and injury and trauma), the most recent GBD health estimates reaffirm a worrying trajectory of increasing global disability for many conditions and in many nations a burden-system response gap persists and will widen [11][12][13]. Without system-level reform efforts and harnessing emerging opportunities for prevention and management of musculoskeletal impairment, an enduring disease burden and persisting inequity in access to care and health outcomes will continue. ...
... This T2T principle has been a key concept in driving better outcomes for adults with rheumatoid arthritis, as evidenced by a wealth of research subsequent to these recommendations [2]. It is now considered the standard of care for adults with RA [3][4][5] and has been adapted for other rheumatological disorders, such as ankylosing spondylitis [6], psoriasis [6], systemic lupus erythematosus [7], and more recently in knee osteoarthritis [8] and osteoporosis [9]. In RA, the utilisation of the T2T strategy has been demonstrated to be more important than the therapeutic agent itself [10][11][12][13], with one small meta-analysis suggesting that protocol-driven tight control may have additional benefit [14]. ...
... Upskill local health professionals through high-quality, evidence-based education and training: Provision of highquality education and training for health professionals responsible for treating osteoarthritis in these settings is essential to improving the delivery of care. 88 Providing education and training on how to diagnose, monitor, and manage osteoarthritis can empower and enable primary health professionals in these lower-resourced settings to provide the key evidenced-based treatments. It can also help primary healthcare professionals understand when to refer patients to specialists or allied health. ...
... Menopauseassociated bone loss is highly treatable, yet few women in this study reported using such treatments, raising concerns over equitable access to healthcare. The HIV clinics in South Africa could consider routine bone health assessment in older menopausal women, and new tools (i.e., the new South African FRAX tool) (69) are now available for this purpose. Future longitudinal studies on fracture incidence in aging women with HIV are warranted. ...
... To date, some studies were reported about the change of rheumatology practice in clinicians during the early pandemic [10][11][12][13][14][15][16][17][18]. To our knowledge, as of the first anniversary of the pandemic, changes in the rheumatology practice point of view of the clinician have not previously been reported in any countries. ...
... The benefits of tele-education was more evident in its ability to reach rheumatologists worldwide with the increase of educational content being moved to online platforms inspired/necessitated by the COVID-19 restrictions which has enabled education to be delivered in a more inclusive manner. [60] Rheumatology societies across the world increased their provision of online resources, such as webinars. Teaching sessions delivered on virtual platforms, such as Zoom or Microsoft Teams, enable interaction through live video audience participation or can be watched on demand. ...
... The COVID-19 pandemic drastically altered the way rheumatologists provide clinical care, forcing the rapid adoption of telehealth for patients with rheumatoid arthritis (RA) and other rheumatologic disorders. More than 95% of health centers across the United States offered telehealth services during the COVID-19 pandemic (1), and reports from rheumatology practices across the globe indicate that between 40% and 90% of rheumatology encounters occurred via telehealth during the initial COVID-19 transition (2)(3)(4)(5)(6)(7)(8). ...
... Meyers et al., found diuretic use in 78 of 92 women with gout. The same observation has been made by other authors (18% of premenopausal women developed diuretic-induced gout, and tophaceous gout in women abusing diuretics for weight loss purposes) [6,9]. In addition, in our patient, arterial hypertension was certainly the favoring factor that fits into the metabolic syndrome. ...
... The coronavirus disease 2019 (COVID-19) pandemic has caused a significant burden on healthcare systems around the world, leading to substantial changes to treatment settings for patients with rheumatic diseases and inflammatory bowel disease (IBD) [1][2][3][4]. The highly transmissible nature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) increases the risk of nosocomial infection [5,6]; thus, outpatient clinics and hospital attendance have been reduced in order to improve physical distance for those patients who still need to attend in person [3,4,[7][8][9]. Minimised patient management via telemedicine has become an important tool in the management of chronically ill patients [3,4,[7][8][9]. However, ongoing concerns about acquiring COVID-19 have prompted some patients to avoid appointments or stop the use of parenteral medication [10], although continued treatments are needed to avoid disease flares [4,[7][8][9]. ...
... Osteoporosis has a high prevalence rate in Africa. In Egypt, for example, about one-fifth of men and one-third of women are affected [4]. ...