Åsa Thelaus’s research while affiliated with Karolinska Institutet and other places

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Publications (1)


Table 2 : Linear and logistic regression analyses with crude and adjusted outcomes. Potential confounders adjusted for are age, sex, ASA class, and cognitive dysfunction. Only the exposure variable (group) and confounders with í µí± values ≤ 0.05 are presented. 
A Prospective Observational Cohort Study on Orthopaedic and Anaesthetic Registrars Performing Femoral Nerve Block on Patients with an Acute Hip Fracture
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January 2016

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1 Citation

Surgery Research and Practice

Åsa Thelaus

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Tobias Pettersson

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We investigated if a femoral nerve block (FNB) for patients with a proximal femoral fracture (PFF) and administered by an orthopaedic registrar (OR) instead of an anaesthesiology registrar (AR) lowers the lead time to block and reduces the total amount of rescue analgesics during the preoperative phase. 205 patients were included in a prospective observational cohort study. The main outcome variable was rescue analgesics as total intravenous morphine prior to surgery. All results were adjusted for confounding using age, sex, cognitive dysfunction, and ASA classification. The OR group ( n = 135 ) was over 2 hours faster in performing the block compared to the AR group ( n = 70 ) but was nonetheless correlated with an increased amount of rescue analgesics during the study, 2.4 mg morphine (95% CI 0.0–4.9) more compared to the AR group. We found no difference between the groups in the risk of adverse events. We conclude that, for patients with an acute PFF and with morphine consumption as end point, how soon from arrival to hospital the patients receive a FNB is of lesser importance than who is administering it. Based on our results we recommend that emergency hospitals should have routines for anaesthesiologists performing FNB on this frail patient group.

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Citations (1)


... DAGs have been used widely throughout clinical medicine to identify the minimum set of confounders in order to reduce bias in studies of assessing causation. Examples include nephrology [11], cardiology [12], feto-maternal medicine [13] and orthopaedics [14]. To our knowledge we are the first group to use DAG theory in a study of PLHIV. ...

Reference:

Non-AIDS complexity amongst patients living with HIV in Sydney: Risk factors and health outcomes
A Prospective Observational Cohort Study on Orthopaedic and Anaesthetic Registrars Performing Femoral Nerve Block on Patients with an Acute Hip Fracture

Surgery Research and Practice