Arumugam Selva Sharma's research while affiliated with Jiangsu University and other places

Publications (26)

Article
In this work, single-step reduction method for the synthesis of highly stable water-soluble copper nanoclusters (CuNCs) at ambient conditions in which Thunnus albacares fish protein (FP) played the dual role of a capping and reducing agent is reported. The physicochemical properties of the prepared CuNCs were characterized by using UV-Visible Spect...
Article
The versatile photophysicalproperties, high surface‐to‐volume ratio, superior photostability, higher biocompatibility, and availability of active sites make graphene quantum dots (GQDs) an ideal candidate for applications in sensing, bioimaging, photocatalysis, energy storage, and flexible electronics. GQDs‐based sensors involve luminescence sensor...
Article
Pathogenic bacteria and their metabolites are the leading risk factor in food safety and are one of the major threats to human health because of the capability of triggering diseases with high morbidity and mortality. Nano-optical sensors for bacteria sensing have been greatly explored with the emergence of nanotechnology and artificial intelligenc...
Article
In this study, a novel analytical approach is proposed for the identification of pesticide residues in tea by combining surface-enhanced Raman scattering (SERS) with a deep learning method one-dimensional convolutional neural network (1D CNN). First, a handheld Raman spectrometer was used for rapid on-site collection of SERS spectra. Second, the co...
Article
In the present study, the multifunctional applications of food waste derived carbon quantum dots (CQD) have been demonstrated. The results obtained from the absorption and fluorescence spectroscopic analysis affirmed the superior photophysical property of the prepared CQD. X-ray diffraction (XRD), Fourier transformed infra-red spectroscopy (FT-IR),...
Article
Full-text available
In recent era bacteria that were previously susceptible to different antibiotics are getting tolerant to these drugs. Novel nanoantibiotics can evade these emerging bacterial resistances. Thus, cefadroxil was conjugated to silver and gold nanoparticles (NPs) and resultant nanoconjugates (i.e., Cefd-AgNPs and Cefd-AuNPs) were examined against staphy...
Article
Noble bimetallic and trimetallic nanoparticles (NBT-NPs) have superior biomedical applications as compared to their monometallic counterparts. The performance of these nanomaterials depends on their composition, shape and size. Hence, the controlled-synthesis of these nanomaterials is a hot area of research. Till date, no review article in the lite...
Article
In the present investigation, a detailed spectroscopic analysis on the interaction mechanism of 1-Butyl-2,3-dimethylimidazolium tetrafluoroborate [Bdmim][BF4] with human serum albumin (HSA) and bovine serum albumin (BSA) has been carried out by multispectroscopic studies. The results obtained from the fluorescence titration experiments indicated th...
Article
Full-text available
A dual (colorimetric and fluorometric) method is described for sensitive and selective determination of the herbicide glyphosate. It is based on the use of a system composed of polyethylenimine-capped NaGdF4:Yb,Er upconversion nanoparticles (UCNPs), copper(II) ions, hydrogen peroxide and 3,3′,5,5′-tetramethylbenzidine. The physicochemical and photo...
Article
This study explores the adsorption and binding interaction of bovine hemoglobin (BHb) and lysozyme (Lys) with gold/silver alloy nanoparticles (Au/Ag alloy NPs) using various spectroscopic approaches. The fluorescence behaviour of tryptophan residues of the proteins after Au/Ag alloy NPs addition revealed that the static quenching interactions. The...
Article
Unique characteristics displayed by phytoconstituent conjugated nanoparticles and their crucial interactions with proteins serve to develop nanoparticle-bio-interface platform. Gold nanoparticles of 16 nm in size were generated using aqueous extracts of pine bark and further conjugated to human serum albumin. The gold nanoparticles-protein complex...
Article
This work reports high-performance supercapattery and lithium-ion storage using nanostructured spinel cobalt oxide (Co3O4) generated by modified facile sol-gel process. The formation of spinel Co3O4 was confirmed by materials characterization techniques. Electrochemical studies of the Co3O4 in KOH revealed excellent redox features. The supercapatte...
Article
In this work, a facile one step solution combustion method was applied to generate Nickel-nickel ferrite@Carbon nanocomposite using glycine as a fuel. The formation of metal ferrite@carbon phase was confirmed by X-ray diffraction, Raman and Fourier transformed infrared spectroscopy analyses. Field emission scanning electron microscope/energy disper...
Article
Full-text available
In this work, a simple sol–gel method was developed to incorporate Co3O4 into glass waste-derived SiO2 to generate a heterostructured SiO2@Co3O4 nanocomposite. Morphological analysis revealed the presence of tiny Co3O4 grains embedded on to the surface of the spherically shaped SiO2 particles. The SiO2@Co3O4 hetrostructure anode exhibited a reversi...
Article
We demonstrate here a sustainable approach to generate carbon-quantum dot (CQD) using denatured (spoiled) milk by a simple one-step hydrothermal method. The unique photophysical property of the CQD has resulted in selective sensing of the chromium ions (Cr6+) as low as 14 µM in control and environmental water samples. The CQD electrode delivered a...
Article
Full-text available
The present investigation elucidates a simple hydrothermal method for preparing nanostructured bismuth oxide (Bi2O3) and carbon quantum dot (CQD) composite using spoiled (denatured) milk-derived CQDs. The formation of the CQD–Bi2O3 composite was confirmed by UV–vis absorption, steady-state emission, and time-resolved fluorescence spectroscopy studi...
Article
Full-text available
In this investigation, we have attempted a novel solution-based strategy to prepare nanostructured silicon oxide@nickel oxide (SiO2@NiO) composite by incorporating NiO into the matrix of the laboratory glass-waste-derived SiO2. The crystal structure and surface functional groups of the prepared composite were investigated by X-ray diffraction (XRD)...
Article
Zinc oxide nanospheres (ZnO) were synthesized by modified sol-gel route using zinc nitrate as precursor and citric acid as gelling agent. Yttria-stabilized zirconia (YSZ)-based sensor was fabricated using the sol-gel derived ZnO nanospheres as sensing electrode and Pt as reference electrode. The sensing characteristics were examined in the temperat...
Article
We report here synthesis of nanostructured MnO2 by using carbon‐quantum dot (CQD) as reducing agent which is obtained by environmentally benign approach from waste material. The obtained carbon quantum dot‐MnO2 nanohybrid is characterized by various analytical techniques. The spectral studies reveal the characteristic absorption/emission features o...
Article
Full-text available
In the present work, we have developed a label free, colorimetric and non aggregation based gold nanoparticle (Au NPs)/Ascorbic acid (AA) probe without employing any aggregation agents for detection of trace amounts of silver ions (Ag⁺ ions) in aqueous solution and water samples. This detection probe can be prepared by simply mixing Au NPs with AA....
Article
In the present investigation, we have systematically studied the binding mechanism of model protein human serum albumin (HSA) with Gold/Silver alloy nanoparticles (Au/Ag NPs) using multi spectroscopic techniques. Absorption spectral studies of Au/Ag NPs in the presence of increasing concentrations of HSA resulted in slight red shift of Au/Ag NPs su...
Article
In the present work, we have carried out a detailed investigation on the binding interaction of acridine orange (AO) with borate capped gold nanoparticles (Au NPs) by absorption spectroscopy, steady state emission spectroscopy, time resolved fluorescence spectroscopy, high resolution transmission electron microscopy (HR- TEM), dynamic light scatter...
Article
In the present study the interaction of chemotherapeutic agent, Azure A (AZA) with Human serum albumin (HSA) and Bovine serum albumin (BSA) was investigated by multi spectroscopic and molecular docking methods. The influence of inner filter effect (IFE) on the emission quenching of HSA/BSA at low concentration of AZA (absorption value < 0.1) sugges...
Article
In the present investigation the interaction of a biologically active photodynamic therapeutic agent Toluidine blue O (TBO) with Serum albumins viz Human serum albumin (HSA) and Bovine serum albumin (BSA) was studied using absorption, emission, circular dichroism spectroscopy and molecular docking experiments. The emission titration experiments bet...

Citations

... In recent years, fluorescence-based detection has aroused increasing attention attributed to its advantages of high sensitivity, short response time, and use of simple instrumentation (Sharma et al., 2021). However, this sensing strategy suffers from some drawbacks. ...
... Therefore, it is crucial to screen foods contaminated by pathogenic bacteria in their supply chains for ensuring food safety. At present, the gold standard bacterial detection method, culture plating, cannot meet the requirement for rapid screening of bacteria (Xu et al., 2021). Although the recommended rapid detection methods, PCR and ELISA, have reduced assay time to several hours, they are still not suitable for on-site detection due to complex operation, expensive instrument or well-trained technician. ...
... The accuracy of the qualitative determination was 100% and the accuracy of the quantification of cocaine in saliva was 98.3% [138]. Deep learning networks such as multilayer perceptron (MLP), fully connected network (FNN), convolutional neural network (CNN), recurrent neural network (RNN), fully convolutional network (FCN), and principal component analysis network (PCA) Net), among others, have also been applied to the analysis of SERS spectra [139][140][141]. Lussier et al. reported the application of ANN combined with SERS. ...
... Additionally, graphite, nanodiamonds, and activated carbon can be applied as precursor for the fabrication of CDs [14]. Meanwhile, a variety of green carbon precursors have been utilized for generating CDs, including fruits, their juices and peels [15][16][17], animal and animal-derived materials, such as milk and hair [18][19][20], and vegetables [21], flowers [22], and leaves [23]. The use of green, sustainable or waste materials for the production of CDs is congruous with the objectives of a sustainable development strategy. ...
... A reducing agent converts metal ions to nanometal during the synthesis of nanoparticles, particularly MNPs [73]. However, some reducing chemicals are known to interact with stabilizer molecules-this then solves the problem of reducing and capping at the same time [74,75]. The reduction mechanism of Ag ion (Ag + ), known as state one to (Ag 0 ) state zero by the phytochemical terpenoid, is depicted in Figure 1. ...
... In addition, the absorption intensity at 279 nm increased along with red shift compared to OVA. It is well known that complex formation between ligand and protein often results in a change in the absorption spectrum of the protein (Lakowicz, 2006;Manivel et al., 2015;Sharma et al., 2020). Overall, the observed increase in absorption intensity at 279 nm with the addition increasing concentrations of 5-CQA clearly demonstrates the formation of ground state complex between 5-CQA and OVA (Abdullah et al., 2017;Shanmugaraj et al., 2017;Tang et al., 2016). ...
... UCNPs fluorescence probes combined with fluorescence analysis are often used in material analysis to use their luminescent properties. Fluorescent determination often utilizes fluorescence labeling or label-free fluorescence techniques [89,90]. The fluorescence labeling method presupposes labeling and separation of the sample from the target analyte, and the label-free fluorescence techniques are accomplished primarily by quenching, reducing, or restoring fluorescence affected by the analyte. ...
... The shape and position of the soret band of Hb confer data about the feasible perturbation of Hb [38,39]. A significant change in the peak position, peak shape, and the maximum intensity (absorbance) of the soret band (Fig. 6B, C, and [40]. Figure 6B represents the typical absorbance of Ag NPs, Hb, and Ag NPs-Hb conjugate with the use of C Ag = 50 μM. ...
... The antibacterial activity of NPs depends on various factors such as their chemical composition, shape, and size [8]. With significant developments in the understanding of nanosystems, some strategies to enhance NPs' activity have been assessed, including combining treatment of NPs and irradiation [9], coating NPs with several coating agents [10], and conjugating NPs with antibiotics [11,12]. Among the widely employed nanoparticles to date, silver nanoparticles (Ag-NPs) have been significantly researched [13][14][15]. ...
... from active fraction and isolated compounds were made to dock with human serum albumin (HSA) to find the subsequent drug-binding capacity, which was selected from PDB ID: 41W2 complexed with glucose [41]. External complex ligands from the selected receptors were eliminated and made ready to dock using Discovery Studio software by script selection. ...