Arthur R Ablin’s research while affiliated with University of California, San Francisco and other places

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Publications (23)


Lymphocyte reconstitution in children receiving soybean agglutinin T-depleted bone marrow transplants
  • Article

March 1987

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11 Reads

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6 Citations

Transplantation Proceedings

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T McHugh

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W Smith

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[...]

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D Stites


Location of the retinoblastoma susceptibility gene(s) and the human esterase D Locus

May 1984

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18 Reads

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67 Citations

Journal of Medical Genetics

Retinoblastoma occurs with increased frequency in children born with a deletion of the long arm of chromosome 13. Recent reviews have noted that the region 13q14 is consistently deleted in documented cases. Prometaphase and late prophase banding allowed Yunis and Ramsay to determine that a deletion in one patient included the sub-bands q14 . 12, q14 . 13, and q14 . 2, and a portion of q14 . 11 and q14 . 3. We report the results of similar cytogenetic techniques applied in the case of a 26 month old Caucasian female with unilateral retinoblastoma, moderate developmental delay, and subtle dysmorphology. Prometaphase banding of cultured skin fibroblasts revealed the karyotype: mos46,XX/46,XX,del(13)(q13 . 1q14 . 11). Only the sub-band q14 . 11 is deleted in both our patient and that of Yunis and Ramsay. The results are consistent with the localisation of the retinoblastoma susceptibility gene(s) in the sub-band 13q14 . 11. Electrophoretic analysis and activity assays of red blood cell esterase D are consistent with hemizygous expression of that marker in our proband. Comparison with published esterase D analyses in families with retinoblastoma permits the assignment of the esterase D locus to that same sub-band, 13q14 . 11.


Citations (20)


... Percentages were reported mainly in publications from the US with elective health insurance. Reported health insurance coverage rates for adult CACS in the US ranged between 80 and 90% [5,40,53,60,64,65,69]. Nonetheless, compared to siblings, survivors were more likely to report underinsurance and less likely to perceive their coverage as stable [51]. ...

Reference:

Insurance, legal, and financial hardships of childhood and adolescent cancer survivors—a systematic review
Education, employment, insurance, and marital status among 694 survivors of pediatric lower extremity bone tumors: A report from the Childhood Cancer Survivor Study
  • Citing Article
  • May 2003

... Palliative Care (PC) is as integrated care model in health services, which seeks to promote dignity and improve the quality of life and well-being of patients and families facing chronic and progressive life-threatening illnesses (Neto, 2021). According to the World Health Organization (World Health Organization [WHO], 2002) and the Strategic Plan for the Development of Palliative Care (2021)(2022), the main objective of PC is to prevent and alleviate suffering, rooted in a multidisciplinary, global and holistic approach and multiple dimensions (physical, psychological, social, spiritual, and existential), through the early identification and treatment of pain or other physical, psychosocial and spiritual needs (Associação Portuguesa de Cuidados Paliativos, 2017;European Association Palliative Care, 2018;Kon & Ablin, 2010;Neto, 2017;Ordem dos Psicólogos Portugueses [OPP], 2019). ...

Palliative Treatment: Redefining Interventions To Treat Suffering Near the End of Life
  • Citing Article
  • Full-text available
  • June 2010

Journal of Palliative Medicine

... A majority of these procedures involve intravenous access, feeding access, or tracheostomy placement for mechanical ventilation. Despite advances in pediatric palliative care, parents report that they do not feel that their children's symptoms are being controlled well at the end of life (9)(10)(11)(12)(13). One study highlighted the magnitude and often short time from invasive procedures to the time of death experienced by some children (14). ...

It's not palliative care, it's palliative treatment
  • Citing Article
  • March 2009

The Lancet Oncology

... Maintaining a child's education is a critical way to provide a sense of normalcy and help prevent the crushing isolation that many students with cancer have reported (Bessell, 2001;Spinetta et al., 2009;Gartin & Murdick, 2009). Research indicates that the needs of students with chronic health needs are not consistently addressed in public schools (Knauer et al., 2015;Selekman, 2017). ...

Optimal care for the child with cancer: A summary statement from the SIOP Working Committee on Psychosocial Issues in Pediatric Oncology
  • Citing Article
  • July 2009

Pediatric Blood & Cancer

... A bi-cultural (or bi-lingual) worker is a research assistant who will be employed to work on the research project to overcome linguistic barriers in cross-cultural research (Shklarov, 2007;Hennink, 2008;Davies et al., 2009;Salma et al., 2017;Stevano & Deane, 2019;O'Rourke et al., 2022). Bi-cultural researchers share not only the language with the participants but also many social and cultural aspects. ...

Conducting a Qualitative Culture Study of Pediatric Palliative Care

... B-cell as well as T-cell recovery is probably functional, as normal levels of IgM and IgA and a normal response of lymphocytes to T-and B-cell mitogens have been demonstrated after CBT (Locatelli et al, 1996;Abu-Ghosh et al, 1999;Knutsen & Wall, 1999;Thomson et al, 2000). Most data on immune reconstitution after stem cell transplantation in children are on TCD bone marrow grafts (Cowan et al, 1987;Daley et al, 1987;Foot et al, 1993;Kook et al, 1996;Small et al, 1999). The detailed analysis of Kook et al (1996) on immune reconstitution after TCD BMT in 102 children reported normalization (defined as . ...

Lymphocyte reconstitution in children receiving soybean agglutinin T-depleted bone marrow transplants
  • Citing Article
  • March 1987

Transplantation Proceedings

... The locus contains the RB1 RBL gene, a tumor suppressor gene originally isolated by Friend et al. (15). LOH is caused by either deletion of the chromosomal locus (16) or mutation of the RB1 gene (17), and is detected not only in RBL but also in other malignancies such as osteosarcoma (18), breast cancer (19) and small cell lung cancer (20). Hereditary RBL patients are at an increased risk of developing osteosarcomas (7,21). ...

Location of the retinoblastoma susceptibility gene(s) and the human esterase D Locus
  • Citing Article
  • May 1984

Journal of Medical Genetics

... Alguns estudos apontam uma breve relação entre genética (incluindo os genes BRAF ou MAP2K1) além de estilo de vida, e condições do sistema imunológico, podendo acometer todas as faixas etárias, mas sendo mais comum em criança (acometendo 0,5 para cada 100.000 crianças por ano). Embora possa ocorrer em qualquer idade, é mais comum na população pediátrica, especialmente em crianças de 0 a 15 anos (Lichtman, 2017;Willis et al., 1996). ...

Disease course and late sequelae of Langerhans' cell Histiocytosis: 25- year experience at the University of California, San Francisco
  • Citing Article
  • August 1996

Journal of Clinical Oncology

... members. [5][6][7] Guidelines and recommendations regarding psychosocial care and communication in pediatric oncology have been available for many years, [8][9][10] but there are few scientifically evaluated psychosocial interventions. A systematic review 11 found that only 2 of 173 interventions in pediatric oncology included siblings. ...

SIOP Working Committee on psychosocial issues in pediatric oncology: Guidelines for communication of the diagnosis
  • Citing Article
  • June 1997

Medical and Pediatric Oncology

... members. [5][6][7] Guidelines and recommendations regarding psychosocial care and communication in pediatric oncology have been available for many years, [8][9][10] but there are few scientifically evaluated psychosocial interventions. A systematic review 11 found that only 2 of 173 interventions in pediatric oncology included siblings. ...

Guidelines for a therapeutic alliance between families and staff: A report of the SIOP Working Committee on Psychosocial Issues in Pediatric Oncology
  • Citing Article
  • April 1998

Medical and Pediatric Oncology