March 1987
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11 Reads
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6 Citations
Transplantation Proceedings
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March 1987
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11 Reads
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6 Citations
Transplantation Proceedings
September 1986
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8 Reads
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1 Citation
Clinical Nuclear Medicine
May 1984
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18 Reads
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67 Citations
Journal of Medical Genetics
Retinoblastoma occurs with increased frequency in children born with a deletion of the long arm of chromosome 13. Recent reviews have noted that the region 13q14 is consistently deleted in documented cases. Prometaphase and late prophase banding allowed Yunis and Ramsay to determine that a deletion in one patient included the sub-bands q14 . 12, q14 . 13, and q14 . 2, and a portion of q14 . 11 and q14 . 3. We report the results of similar cytogenetic techniques applied in the case of a 26 month old Caucasian female with unilateral retinoblastoma, moderate developmental delay, and subtle dysmorphology. Prometaphase banding of cultured skin fibroblasts revealed the karyotype: mos46,XX/46,XX,del(13)(q13 . 1q14 . 11). Only the sub-band q14 . 11 is deleted in both our patient and that of Yunis and Ramsay. The results are consistent with the localisation of the retinoblastoma susceptibility gene(s) in the sub-band 13q14 . 11. Electrophoretic analysis and activity assays of red blood cell esterase D are consistent with hemizygous expression of that marker in our proband. Comparison with published esterase D analyses in families with retinoblastoma permits the assignment of the esterase D locus to that same sub-band, 13q14 . 11.
... Percentages were reported mainly in publications from the US with elective health insurance. Reported health insurance coverage rates for adult CACS in the US ranged between 80 and 90% [5,40,53,60,64,65,69]. Nonetheless, compared to siblings, survivors were more likely to report underinsurance and less likely to perceive their coverage as stable [51]. ...
May 2003
... Palliative Care (PC) is as integrated care model in health services, which seeks to promote dignity and improve the quality of life and well-being of patients and families facing chronic and progressive life-threatening illnesses (Neto, 2021). According to the World Health Organization (World Health Organization [WHO], 2002) and the Strategic Plan for the Development of Palliative Care (2021)(2022), the main objective of PC is to prevent and alleviate suffering, rooted in a multidisciplinary, global and holistic approach and multiple dimensions (physical, psychological, social, spiritual, and existential), through the early identification and treatment of pain or other physical, psychosocial and spiritual needs (Associação Portuguesa de Cuidados Paliativos, 2017;European Association Palliative Care, 2018;Kon & Ablin, 2010;Neto, 2017;Ordem dos Psicólogos Portugueses [OPP], 2019). ...
June 2010
Journal of Palliative Medicine
... A majority of these procedures involve intravenous access, feeding access, or tracheostomy placement for mechanical ventilation. Despite advances in pediatric palliative care, parents report that they do not feel that their children's symptoms are being controlled well at the end of life (9)(10)(11)(12)(13). One study highlighted the magnitude and often short time from invasive procedures to the time of death experienced by some children (14). ...
Reference:
Pediatric palliative care and surgery
March 2009
The Lancet Oncology
... Maintaining a child's education is a critical way to provide a sense of normalcy and help prevent the crushing isolation that many students with cancer have reported (Bessell, 2001;Spinetta et al., 2009;Gartin & Murdick, 2009). Research indicates that the needs of students with chronic health needs are not consistently addressed in public schools (Knauer et al., 2015;Selekman, 2017). ...
July 2009
Pediatric Blood & Cancer
... A bi-cultural (or bi-lingual) worker is a research assistant who will be employed to work on the research project to overcome linguistic barriers in cross-cultural research (Shklarov, 2007;Hennink, 2008;Davies et al., 2009;Salma et al., 2017;Stevano & Deane, 2019;O'Rourke et al., 2022). Bi-cultural researchers share not only the language with the participants but also many social and cultural aspects. ...
January 2009
... B-cell as well as T-cell recovery is probably functional, as normal levels of IgM and IgA and a normal response of lymphocytes to T-and B-cell mitogens have been demonstrated after CBT (Locatelli et al, 1996;Abu-Ghosh et al, 1999;Knutsen & Wall, 1999;Thomson et al, 2000). Most data on immune reconstitution after stem cell transplantation in children are on TCD bone marrow grafts (Cowan et al, 1987;Daley et al, 1987;Foot et al, 1993;Kook et al, 1996;Small et al, 1999). The detailed analysis of Kook et al (1996) on immune reconstitution after TCD BMT in 102 children reported normalization (defined as . ...
March 1987
Transplantation Proceedings
... The locus contains the RB1 RBL gene, a tumor suppressor gene originally isolated by Friend et al. (15). LOH is caused by either deletion of the chromosomal locus (16) or mutation of the RB1 gene (17), and is detected not only in RBL but also in other malignancies such as osteosarcoma (18), breast cancer (19) and small cell lung cancer (20). Hereditary RBL patients are at an increased risk of developing osteosarcomas (7,21). ...
May 1984
Journal of Medical Genetics
... Alguns estudos apontam uma breve relação entre genética (incluindo os genes BRAF ou MAP2K1) além de estilo de vida, e condições do sistema imunológico, podendo acometer todas as faixas etárias, mas sendo mais comum em criança (acometendo 0,5 para cada 100.000 crianças por ano). Embora possa ocorrer em qualquer idade, é mais comum na população pediátrica, especialmente em crianças de 0 a 15 anos (Lichtman, 2017;Willis et al., 1996). ...
August 1996
Journal of Clinical Oncology
... members. [5][6][7] Guidelines and recommendations regarding psychosocial care and communication in pediatric oncology have been available for many years, [8][9][10] but there are few scientifically evaluated psychosocial interventions. A systematic review 11 found that only 2 of 173 interventions in pediatric oncology included siblings. ...
June 1997
Medical and Pediatric Oncology
... members. [5][6][7] Guidelines and recommendations regarding psychosocial care and communication in pediatric oncology have been available for many years, [8][9][10] but there are few scientifically evaluated psychosocial interventions. A systematic review 11 found that only 2 of 173 interventions in pediatric oncology included siblings. ...
April 1998
Medical and Pediatric Oncology