Arthur E. Guedel's scientific contributions

Citations

... The patients undergoing the first thoracotomies were mildly anesthetized and they were breathing spontaneously, however, the outcome of these procedures was unfavorable. Soon after the invention of the endotracheal tube by Guedel in 1928, the idea of advancing it into the main bronchus of the healthy lung arose in order to avoid the ventilation of the surgical site, thus the one-lung ventilation (OLV) technique was born (1,4). OLV was combined with mechanical ventilation after its appearance in the 1960s. ...
... These initial designs received successive modifications between 1923 and 1932, enabling the joint administration of nitrous oxide and oxygen, and the incorporation of gas flow meters. [50,51] In 1924, Ralph Waters introduced the use of granules for the absorption of carbon dioxide. [52] Based on the closed circuit proposed by Jackson in 1915, Brian C. Sword designed an anesthetic machine in 1930, which incorporated the first closed-circle circuit with carbon dioxide absorption through the Waters granules, which were composed of 50% calcium oxide and 50% sodium hydroxide. ...