Antonietta Aversano's research while affiliated with University of Naples Federico II and other places

Publications (3)

Article
Full-text available
Balneotherapy and spa therapy have been used in the treatment of ailments since time immemorial. Moreover, there is evidence to suggest that the beneficial effects of thermal water continue for months following the completion of treatment. The mechanisms through which thermal water exerts its healing effects remain unknown. Both balneological and h...
Article
Familial adenomatous polyposis (FAP) is an autosomal dominant hereditary precancerous condition caused by germline pathogenetic variants in the tumor suppressor adenomatous polyposis coli (APC) gene. Patients with FAP develop multiple gastrointestinal adenomatous polyps usually at the age of ~20 years, which, if untreated, become cancerous in 100%...
Article
Full-text available
Colorectal cancer (CRC) is the third most prevalent type of cancer worldwide. It is also the second most common cause of cancer‑associated mortality; it accounted for about 9.2% of all cancer deaths in 2018, most of which were due to resistance to therapy. The main treatment for CRC is surgery, generally associated with chemotherapy, radiation ther...

Citations

... To set up the optimal conditions and discriminate apoptotic cells from live cells, we used RKO and HEK 293T untreated cells as internal controls in these experiments. When these cells were induced to undergo apoptosis by a 24 h treatment with 60 mM LiCl, a GSK3β inhibitor known to induce apoptosis in several human cell lines [35][36][37], they exhibited a high percentage of subdiploid cells ( Figure 3A). In contrast, when Dox-treated RKO and HEK 293T cells were analyzed for their DNA content, they presented only a negligible percentage of the subdiploid peak ( Figure 3A), indicating that they are not subjected to apoptosis. ...