Andrew Gelman’s research while affiliated with Columbia University and other places

Compartmental models that describe infectious disease transmission across subpopulations are central for assessing the impact of non-pharmaceutical interventions, behavioral changes and seasonal effects on the spread of respiratory infections. We present a Bayesian workflow for such models, including four features: (1) an adjustment for incomplete case ascertainment, (2) an adequate sampling distribution of laboratory-confirmed cases, (3) a flexible, time-varying transmission rate, and (4) a stratification by age group. Within the workflow, we benchmarked the performance of various implementations of two of these features (2 and 3). For the second feature, we used SARS-CoV-2 data from the canton of Geneva (Switzerland) and found that a quasi-Poisson distribution is the most suitable sampling distribution for describing the overdispersion in the observed laboratory-confirmed cases. For the third feature, we implemented three methods: Brownian motion, B-splines, and approximate Gaussian processes (aGP). We compared their performance in terms of the number of effective samples per second, and the error and sharpness in estimating the time-varying transmission rate over a selection of ordinary differential equation solvers and tuning parameters, using simulated seroprevalence and laboratory-confirmed case data. Even though all methods could recover the time-varying dynamics in the transmission rate accurately, we found that B-splines perform up to four and ten times faster than Brownian motion and aGPs, respectively. We validated the B-spline model with simulated age-stratified data. We applied this model to 2020 laboratory-confirmed SARS-CoV-2 cases and two seroprevalence studies from the canton of Geneva. This resulted in detailed estimates of the transmission rate over time and the case ascertainment. Our results illustrate the potential of the presented workflow including stratified transmission to estimate age-specific epidemiological parameters. The workflow is freely available in the R package HETTMO, and can be easily adapted and applied to other infectious diseases.

This book provides statistics instructors and students with complete classroom material for a one- or two-semester course on applied regression and causal inference. It is built around 52 stories, 52 class-participation activities, 52 hands-on computer demonstrations, and 52 discussion problems that allow instructors and students to explore in a fun way the real-world complexity of the subject. The book fosters an engaging 'flipped classroom' environment with a focus on visualization and understanding. The book provides instructors with frameworks for self-study or for structuring the course, along with tips for maintaining student engagement at all levels, and practice exam questions to help guide learning. Designed to accompany the authors' previous textbook Regression and Other Stories, its modular nature and wealth of material allow this book to be adapted to different courses and texts or be used by learners as a hands-on workbook.

This book provides statistics instructors and students with complete classroom material for a one- or two-semester course on applied regression and causal inference. It is built around 52 stories, 52 class-participation activities, 52 hands-on computer demonstrations, 52 drills, and 52 discussion problems that allow instructors and students to explore in a fun way the real-world complexity of the subject. The book fosters an engaging “flipped classroom” environment with a focus on visualization and understanding. The book provides instructors with frameworks for self-study or for structuring the course, along with tips for maintaining student engagement at all levels and practice exam questions to help guide learning. Designed to accompany the authors’ previous textbook Regression and Other Stories, its modular nature and wealth of material allow this book to be adapted to different courses and texts or to be used by learners as a hands-on workbook. The authors are experienced researchers who have published articles in hundreds of different scientific journals in fields including statistics, computer science, policy, public health, political science, economics, sociology, and engineering. They have also published articles in the Washington Post, the New York Times, Slate, and other public venues. Their previous books include Bayesian Data Analysis, Teaching Statistics: A Bag of Tricks, and Regression and Other Stories.

This book provides statistics instructors and students with complete classroom material for a one- or two-semester course on applied regression and causal inference. It is built around 52 stories, 52 class-participation activities, 52 hands-on computer demonstrations, and 52 discussion problems that allow instructors and students to explore in a fun way the real-world complexity of the subject. The book fosters an engaging 'flipped classroom' environment with a focus on visualization and understanding. The book provides instructors with frameworks for self-study or for structuring the course, along with tips for maintaining student engagement at all levels, and practice exam questions to help guide learning. Designed to accompany the authors' previous textbook Regression and Other Stories, its modular nature and wealth of material allow this book to be adapted to different courses and texts or be used by learners as a hands-on workbook.

This book provides statistics instructors and students with complete classroom material for a one- or two-semester course on applied regression and causal inference. It is built around 52 stories, 52 class-participation activities, 52 hands-on computer demonstrations, 52 drills, and 52 discussion problems that allow instructors and students to explore in a fun way the real-world complexity of the subject. The book fosters an engaging “flipped classroom” environment with a focus on visualization and understanding. The book provides instructors with frameworks for self-study or for structuring the course, along with tips for maintaining student engagement at all levels and practice exam questions to help guide learning. Designed to accompany the authors’ previous textbook Regression and Other Stories, its modular nature and wealth of material allow this book to be adapted to different courses and texts or to be used by learners as a hands-on workbook. The authors are experienced researchers who have published articles in hundreds of different scientific journals in fields including statistics, computer science, policy, public health, political science, economics, sociology, and engineering. They have also published articles in the Washington Post, the New York Times, Slate, and other public venues. Their previous books include Bayesian Data Analysis, Teaching Statistics: A Bag of Tricks, and Regression and Other Stories.

This book provides statistics instructors and students with complete classroom material for a one- or two-semester course on applied regression and causal inference. It is built around 52 stories, 52 class-participation activities, 52 hands-on computer demonstrations, 52 drills, and 52 discussion problems that allow instructors and students to explore in a fun way the real-world complexity of the subject. The book fosters an engaging “flipped classroom” environment with a focus on visualization and understanding. The book provides instructors with frameworks for self-study or for structuring the course, along with tips for maintaining student engagement at all levels and practice exam questions to help guide learning. Designed to accompany the authors’ previous textbook Regression and Other Stories, its modular nature and wealth of material allow this book to be adapted to different courses and texts or to be used by learners as a hands-on workbook. The authors are experienced researchers who have published articles in hundreds of different scientific journals in fields including statistics, computer science, policy, public health, political science, economics, sociology, and engineering. They have also published articles in the Washington Post, the New York Times, Slate, and other public venues. Their previous books include Bayesian Data Analysis, Teaching Statistics: A Bag of Tricks, and Regression and Other Stories.

This book provides statistics instructors and students with complete classroom material for a one- or two-semester course on applied regression and causal inference. It is built around 52 stories, 52 class-participation activities, 52 hands-on computer demonstrations, and 52 discussion problems that allow instructors and students to explore in a fun way the real-world complexity of the subject. The book fosters an engaging 'flipped classroom' environment with a focus on visualization and understanding. The book provides instructors with frameworks for self-study or for structuring the course, along with tips for maintaining student engagement at all levels, and practice exam questions to help guide learning. Designed to accompany the authors' previous textbook Regression and Other Stories, its modular nature and wealth of material allow this book to be adapted to different courses and texts or be used by learners as a hands-on workbook.